Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

This book begins the Spoken Standard Chinese series, which emphasizes natural dialogue and familiarity with a modern, adult vocabulary. Book One uses pinyin romanization and no Chinese characters. An accompanying audio program is available.

Focusing on basic lubrication problems this book offers specific engineering applications. The book introduces methods and programs for the most important lubrication problems and their solutions. It is divided into four parts. The first part is about the general solving methods of the Reynolds equation, including solutions of Reynolds equations with different conditions and their discrete forms, such as a steady-state incompressible slider, journal bearing, dynamic bearing, gas bearing and grease lubrication. The second part gives the energy equation solution . The third part introduces methods and programs for elasto-hydrodynamic lurbication, which links the Reynolds equation with the elastic deformation equation. The final part presents application lubrication programs used in engineering. * Provides numerical solution methodologies including appropriate software for the hydrodynamic and elasto-hydrodynamic lubrication of bearings * Offers a clear introduction and orientation to all major engineering lubrication problems and their solutions * Presents numerical programs for specific applications in engineering, with special topics including grease-lubricated bearings and gas bearings * Equips those working in tribology and those new to the topic with the fundamental tools of calculation * Downloadable programs are available at the companion website With an emphasis on clear explanations, the text offers a thorough understanding of the numerical calculation of lubrication for graduate students on tribology and engineering mechanics courses, with more detailed materials suitable for engineers. This is an accessible reference for senior undergraduate students of tribology and researchers in thin-film fluid mechanics.