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The potato (Solanum tuberosum L. ) tuber is a major food source in
many countries of the world, and subsequently potato has been the
target of a good deal of effort directed at engineering disease and
herbicide tolerance, and improvements in various crop
characteristics. Consequently investigations into the regulation of
gene expression in tubers is relevant to these endeavours, as
tubers are the main target organ for modification of gene
expression. We have been interested in the regulation of genes in
tubers for these reasons. Morphologically tubers are modified
stems, which have enlarged radially by limited cell division and
substantial expansion. At the molecular level, tuber development is
characterised by a massive increase in starch deposition and the
synthesis of a limited number of abundant proteins. These include
proteinase inhibitors and a 40kd group of proteins called patatin,
which are acyl hydrolases. Together these proteins account for over
50% of tuber proteins (reviewed by Bevan, 1991). The synthesis of
these proteins has parallels to the synthesis of other somatic
storage proteins, especially the VSP proteins of soybean. In both
potato and soybean, removal of the sink for these proteins (tubers
and pods, respectively) causes deposition in other tissues
(Staswick, 1990). It is hypothesised that transcriptional control
of the genes encoding these proteins is regulated in part by
source-sink relationships of metabolites or other factors. In the
case of VSPs, both amino acid levels and jasmonic acid play a major
regulatory role (Staswick et aI.
George Raven served as a police officer in Essex for thirty years,
rising to the rank of Detective Superintendent. In this
autobiography he looks back on a colourful career, recounting
stories of fascinating manhunts, gruesome murders, violent
encounters and heart-rending tragedies - as well as plenty of
amusing and not-so-amusing incidents as he worked alongside
officers who ranged from the excellent to the incompetent. Raven's
conclusion in retirement is that police recruitment standards and
performance have deteriorated alarmingly over the years, while
public perception and trust now stands at its lowest since the
British police force was founded. In this entertaining account of
his life in the force, he examines the reasons and challenges
politicians to address the serious problems facing the police in
the 21st century. 'Politicians pass more and more laws, dream up
more and more regulations and issue more and more directives to the
police, to tie their hands and make enforcing both the good and the
ridiculous laws they pass an almost impossible task.'
The potato (Solanum tuberosum L. ) tuber is a major food source in
many countries of the world, and subsequently potato has been the
target of a good deal of effort directed at engineering disease and
herbicide tolerance, and improvements in various crop
characteristics. Consequently investigations into the regulation of
gene expression in tubers is relevant to these endeavours, as
tubers are the main target organ for modification of gene
expression. We have been interested in the regulation of genes in
tubers for these reasons. Morphologically tubers are modified
stems, which have enlarged radially by limited cell division and
substantial expansion. At the molecular level, tuber development is
characterised by a massive increase in starch deposition and the
synthesis of a limited number of abundant proteins. These include
proteinase inhibitors and a 40kd group of proteins called patatin,
which are acyl hydrolases. Together these proteins account for over
50% of tuber proteins (reviewed by Bevan, 1991). The synthesis of
these proteins has parallels to the synthesis of other somatic
storage proteins, especially the VSP proteins of soybean. In both
potato and soybean, removal of the sink for these proteins (tubers
and pods, respectively) causes deposition in other tissues
(Staswick, 1990). It is hypothesised that transcriptional control
of the genes encoding these proteins is regulated in part by
source-sink relationships of metabolites or other factors. In the
case of VSPs, both amino acid levels and jasmonic acid play a major
regulatory role (Staswick et aI.
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