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This volume is a compilation of lectures delivered at the TASI 2015
summer school, 'New Frontiers in Fields and Strings', held at the
University of Colorado Boulder in June 2015. The school focused on
topics in theoretical physics of interest to contemporary
researchers in quantum field theory and string theory. The lectures
are accessible to graduate students in the initial stages of their
research careers.
Recent studies regarding the neuropathology of specific
neurological disorders suggest that both neurodevelopmental and
neurodegenerative processes may play a role. However, in contrast
to the neurodegeneration seen in neurological disorders such as
Parkinson's and Alzheimer's disease, the term "neuroprogression"
has been used to describe the neurodevelopmental aspect of
pathological brain re-wiring that takes place in the context of
severe psychiatric disorders, such as schizophrenia or bipolar
disorder. Within psychiatry, patients with severe psychopathology,
such as those depressed patients who eventually commit suicide,
have been shown to present with increased inflammatory markers in
the brain. A similar increase in inflammatory markers is also found
in patients with bipolar disorders and schizophrenia. Thus,
oxidative stress, inflammation, and changes in growth factors are
thought to be the pathways of neuroprogression. Neuroprogression in
Psychiatry provides a comprehensive summary of the current
developments in the emerging field of neuroprogression. With
contributions by leading researchers in the field, this book
examines the role of neuroprogression across a wide range of
specific psychiatric disorders, with chapters included on major
depressive disorder, anxiety disorder, post-traumatic stress
disorder, substance abuse, schizophrenia, and bipolar disorder.
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