Since their rapid proliferation in the late 1960s and early 1970s, quadrupole mass spectrometers have had a profound impact across the physical sciences. Geometrically simple, yet behaviorally complex, these dynamic mass analyzers continue to facilitate remarkable breakthroughs in fields ranging from biochemical analysis to process control technology. Long regarded as the standard introduction to the field, Quadrupole Mass Spectrometry and Its Applications provides today's engineers and scientists with an authoritative, wide-ranging overview of the development and uses of quadrupoles. Beginning with the basic operating principles of quadrupole devices, the book moves from general explanations of the actions of radio-frequency fields to descriptions of their utilization in quadrupole mass filters, monopoles, three-dimensional quadrupole ion traps, and various time-of-flight spectrometers. A concluding series of chapters examines early applications of quadrupoles in atomic physics, gas chromatography, upper atmospheric research, medicine, and environmental studies. Superb writing from the field's foremost scientists along with the continued central role of quadrupoles in contemporary research make this volume as timely and relevant as ever.