This ACS Symposium Series book evolved from the ACS symposium "Food Additives and Packaging" sponsored by the Division of Agricultural and Food Chemistry (AGFD) at the 245th ACS National Meeting & Exposition in New Orleans, LA, April 7-11, 2013. The book helps readers understand the rules and regulations governing the use of food additives and food packaging materials in the U.S. and globally. Furthermore, the book investigates novel materials and applications related to food additives and food packaging materials and explores concerns, issues, and current events in the field. The book particularly highlights global regulations, research, development, applications, and evaluation of food additives and food packaging materials. These areas are dynamic, constantly changing, and expected to attract the interest of a broad and diverse readership. Part I of this book highlights how food additives and packaging materials are classified and regulated in different parts of the world and addresses some of the scientific, legal, and practical issues related to these regulations from the perspective representatives. It contains monographs on general aspects of regulatory processes in various countries (U.S., EU, Thailand and Japan) and specific aspects, such as GRAS substances, color additives, enzymes, flavorings, safety assessments, and the National Environmental Policy Act (NEPA). Part II presents some current topics related to the research, development, applications, and evaluation of food additives and food packaging materials, with monographs on applying regulatory knowledge for packaging compliance and evaluating food packaging for pre-packaged irradiated food, and on various emerging technologies, such as a control release packaging system and high pressure processing that can improve the appearance, texture, taste, or shelf-life of food; it also includes monographs that discuss other aspects, such as bisphenol A, PET packaging materials, nanomaterials, and biomaterials.