Even though time-dependent spectroscopic techniques continue to push the frontier of chemical physics, they receive scant mention in introductory courses and are poorly covered in standard texts. Quantum Dynamics: Applications in Biological and Materials Systems bridges the gap between what is traditionally taught in a one-semester quantum chemistry course and the modern field of chemical dynamics, presenting the quantum theory of charge and energy transport in biological systems and optical-electronic materials from a dynamic perspective. Reviews the basics Taking a pedagogical approach, the book begins by reviewing the concepts of classical mechanics that are necessary for studying quantum mechanics. It discusses waves and wave functions and then moves on to an exploration of semiclassical quantum mechanics methods, an important part of the development and utilization of quantum theory. Time-independent and time-dependent perspectives The main focus of the book is the chapter on quantum dynamics, which begins with a brief review of the bound states of a coupled two-level system. This is discussed with a time-independent as well as a time-dependent perspective. The book also explores what happens when the two-level system has an additional harmonic degree of freedom that couples the transitions between the two states. The book reviews different ways in which one can represent the evolution of a quantum state, explores the quantum density matrix, and examines the basis for excitation energy transfer between molecules. Later chapters describe the pi electronic structure of conjugated organic systems and discuss electron-phonon coupling in conjugated systems and transport and dynamics in extended systems. Includes Mathematica (R) downloads On an accompanying website, Mathem

Even though time-dependent spectroscopic techniques continue to push the frontier of chemical physics, they receive scant mention in introductory courses and are poorly covered in standard texts. Quantum Dynamics: Applications in Biological and Materials Systems bridges the gap between what is traditionally taught in a one-semester quantum chemistry course and the modern field of chemical dynamics, presenting the quantum theory of charge and energy transport in biological systems and optical-electronic materials from a dynamic perspective. Reviews the basics Taking a pedagogical approach, the book begins by reviewing the concepts of classical mechanics that are necessary for studying quantum mechanics. It discusses waves and wave functions and then moves on to an exploration of semiclassical quantum mechanics methods, an important part of the development and utilization of quantum theory. Time-independent and time-dependent perspectives The main focus of the book is the chapter on quantum dynamics, which begins with a brief review of the bound states of a coupled two-level system. This is discussed with a time-independent as well as a time-dependent perspective. The book also explores what happens when the two-level system has an additional harmonic degree of freedom that couples the transitions between the two states. The book reviews different ways in which one can represent the evolution of a quantum state, explores the quantum density matrix, and examines the basis for excitation energy transfer between molecules. Later chapters describe the pi electronic structure of conjugated organic systems and discuss electron-phonon coupling in conjugated systems and transport and dynamics in extended systems. Includes Mathematica (R) downloads On an accompanying website, Mathem

Seit der Erstbeschreibung des Pankreaskarzinoms durch Mondiere 1836 ist eine standige Zunahme der Inzidenz des Pankreaskarzinoms zu verzeich- nen; heute ist es eines der haufigsten Malignome des Gastrointestinal- traktes mit etwa 6000 Neuerkrankungen pro Jahr in der Bundesrepublik Deutschland. Das onkologische Basiswissen uber Entstehung, Wachstum sowie Ausbreitung ist sehr luckenhaft; es existiert fur diesen Tumor bisher auch keine spezielle Screening-Methode und es fehlt ein Konzept zur Fruh- diagnose. Der Stand der therapeutischen Moeglichkeiten lasst sich an der Tatsache ablesen, dass nur etwa 10% der Patienten im Tumorstadium I oder 11 diagnostiziert werden; eine Heilung ist bei weniger als 5% aller operierten Patienten zu erwarten. Mit diesem Buch uber das Pankreaskarzinom, das ausgehend von Refe- raten eines Internationalen Symposions auf Schloss Reisensburg bei Ulm entstanden ist, verbindet sich die Hoffnung, in folgenden experimentellen und klinischen Problemen zu einheitlichen Standpunkten zu kommen: 1. Objektivierung von klinisch relevanten Tiermodellen des Pankreaskarzi- noms; 2. Neubewertung der Unterschiede in der pathologisch-anatomischen Klassifikation des Pankreaskarzinoms; 3. Neubewertung aller derzeit zur Diagnostik des Pankreaskarzinoms angewandten histologischen, serologi- schen und instrumentellen Diagnoseverfahren; 4. Definition von Therapie- gruppen und Neubewertung von chirurgischen Therapiemoeglichkeiten mit Standardisierung der resezierenden Therapie. Die in dem Buch von anerkannten nationalen und internationalen Fachkollegen diskutierten Einzelaspekte aus dem Bereich der Onkologie und Pathologie sowie Diagnostik und Therapie, sollen dem interessierten Kli- niker die neuesten Ansatzpunkte bieten, um seinen Patienten mit Pankreaskarzinom besser zu helfen.