One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer s disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal.
The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death.
* This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies.
* Presents key methods on studying tumors and how these cancer cells evade cell death.
* Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over."

This book, by a practicing and successful scientist, explores why questions arise in science and looks at how questions are tackled, what constitutes a valid answer, and why. The author does not bog down the reader in technical details or lists of facts to memorize. Instead, he places the questions in their historical and cultural context, ranging from the earliest intimations that the earth had a long history to current controversies, even describing the origins, challenges, and promises of modern molecular biology. The book should provide an antidote for students who have suffered through science for non-scientists courses that were long lists of names to memorize; and it should prove enlightening for any citizen who has been perplexed by the meaning, relevance, and moral or political implications of scientific headlines or commercial efforts, or anyone who has cast or will cast a vote influenced by a scientific presumption.

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death.
* This volume provides the necessary, trusted methods to carry out this research on the latest techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies.
* Presents key methods on studying tumors and how these cancer cells evade cell death.
* Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.

This book reveals that scientific logic is an extension of common, everyday logic and that it can and should be understood by everyone. Written by a practicing and successful scientist, it explores why questions arise in science and looks at how questions are tackled, what constitutes a valid answer, and why. The author does not bog the reader down in technical details or lists of facts to memorize. He uses accessible examples, illustrations, and descriptions to address complex issues. The book should prove enlightening to anyone who has been perplexed by the meaning, relevance, and moral or political implications of science.