Depression is one of the most common mental health problems facing older people, and it is often unrecognised and usually under-treated. Integrated Management of Depression in the Elderly provides an entirely new approach to understanding late-life depression, by using a series of case studies with commentaries from practitioners internationally. The book covers the epidemiology, presentation and diagnosis of depression in older people and outlines current evidence for effective management drawing on recently published work. The substantive part of the book presents ten case studies of increasing complexity, each case has a commentary from a primary care clinician and a health or social care professional, to outline how professionals should work together to manage the patient within their community. Contributions from world experts give the book an international appeal. It will appeal to a wide audience of health and social care professionals together with psychiatrists-in-training.

Hugh P. Possingham Landscape-scale conservation planning is coming of age. In the last couple of decades, conservation practitioners, working at all levels of governance and all spatial scales, have embraced the CARE principles of conservation planning - Comprehensiveness, Adequacy, Representativeness, and Efficiency. Hundreds of papers have been written on this theme, and several different kinds of software program have been developed and used around the world, making conservation planning based on these principles global in its reach and influence. Does this mean that all the science of conservation planning is over - that the discovery phase has been replaced by an engineering phase as we move from defining the rules to implementing them in the landscape? This book and the continuing growth in the literature suggest that the answer to this question is most definitely 'no. ' All of applied conservation can be wrapped up into a single sentence: what should be done (the action), in what place, at what time, using what mechanism, and for what outcome (the objective). It all seems pretty simple - what, where, when, how and why. However stating a problem does not mean it is easy to solve.

Volume 72 addresses the role of peptide backbone solvation in the energetics of protein folding. Particular attention is focused on modeling and computation. This volume will be of particular interest to biophysicists and structural biologists.
*Challenges the longstanding and basic assumptions of structural biology
*Discusses how to solve the problem of protein structure prediction
*Addresses the quantitation of the energetics of folding

Hugh P. Possingham Landscape-scale conservation planning is coming of age. In the last couple of decades, conservation practitioners, working at all levels of governance and all spatial scales, have embraced the CARE principles of conservation planning - Comprehensiveness, Adequacy, Representativeness, and Efficiency. Hundreds of papers have been written on this theme, and several different kinds of software program have been developed and used around the world, making conservation planning based on these principles global in its reach and influence. Does this mean that all the science of conservation planning is over - that the discovery phase has been replaced by an engineering phase as we move from defining the rules to implementing them in the landscape? This book and the continuing growth in the literature suggest that the answer to this question is most definitely 'no. ' All of applied conservation can be wrapped up into a single sentence: what should be done (the action), in what place, at what time, using what mechanism, and for what outcome (the objective). It all seems pretty simple - what, where, when, how and why. However stating a problem does not mean it is easy to solve.

Between 1977 and 1997, there was a precipitous decline in the proportion of US workers with median education (12 years or less) who were represented by a labor union-from 29 to 14 percent; the unionization proportion declined much less among workers with above-median education (19 to 13 percent). The union wage premium also declined for workers with basic education, from 58 to 51 percent, whereas it rose slightly for better-educated unionists, from 18 to 19 percent. Thus, whatever safety net American unions provide was disproportionately lost by the less-educated workers who, arguably, need it the most. In this study, Robert E. Baldwin investigates the role of changes in US imports and exports in explaining this dramatic decline. The main analysis (which includes workers in manufacturing as well as service sectors) relates changes in the number of union workers across industries to changes in domestic spending, imports, exports, and the intensity with which labor is used across these industries for both union and nonunion workers. Baldwin finds that although globalization (i.e., increased trade) seems to have contributed only modestly to the general decline in unionization, it has, more importantly, contributed to the decline in unionization among workers with less education. The study concludes with a discussion on the implication of this and the other findings for governmental policy and for the policy position of unions toward globalization.

The unwillingness of the US House of Representatives to renew fast-track authority in 1997 and 1998 means that further trade liberalization for the United States is likely to slow down or grind to a halt, since negotiators elsewhere know that any agreements reached could be modified by the US Congress. This political impasse raises several overarching questions: Does the status of fast track represent a temporary or a permanent setback in the postwar trend toward freer trade? Is it due simply to lax efforts in mobilizing groups that support trade liberalization, or is US trade policy becoming more protectionist? More generally, what were the most important economic and social factors shaping congressional voting on trade legislation in the 1990s? How do these factors differ for the various trade bills Congress considered over this period?Baldwin and Magee attempt to answer these questions by analyzing three key trade bills: NAFTA in 1993; the legislation implementing the Uruguay Round agreements in 1994; and the House bill seeking to renew fast-track authority in 1998. The authors provide a brief legislative history of each, and then outline a conceptual framework for their analysis. Focusing on district and state economic conditions, ideological leanings, and campaign contributions, they find both predictable and surprising relationships in the data.