This conference, dedicated to the etiology and treatment of motility disor ders in spermatozoa and male sterility, attracted some of the finest investiga tors in the field. Standards were immensely high throughout, and discussions were meaningful and detailed. Analyses on disorders in sperm motility de mand a broad-based approach, involving cytologists, geneticists, andrologists, and embryologists, because the topic has many clinical and scientific over tones. Human spermatozoa are at the mercy of so many factors as they form and mature in the testis and epididymis. Their survival and fundamental char acteristics are essential for fertilization, and the male genome imposes its influence on the embryo as it becomes active in male pronuclei very soon after sperm entry into the oocyte. All of these fundamental aspects of sperm biology demanded a broad breadth of topics in the symposium. The opening session quickly got down to fundamentals with contributions from J.-L. Gatti, J.G. Alvarez, C. Gagnon, and H. Breitbart. They discussed the mechanism and regulation of motility, the metabolic strategy of human spermatozoa, the effects of exogenous fac tors such as antibodies, infections, and toxins, and finally the role of intracel lular calcium on sperm motility. To these topics, the postcoffee session on the first morning described the genetics of motility disorders and the etiology and management of necrozoospermia. The excellent presentation provided the background detail of the symposium and opened the way for the discus sion of various clinical aspects of the topic.

L'ouvrage a pour objectif de faire le point sur l'itat des connaissances, tant du point de vue fondamental que physiopathologique, des diffirents aspects des gamhtes mbles (de la physiologie l'application clinique). Aprhs avoir exposi les aspects ipidimiologiques et physiologiques, l'ouvrage abordera les aspects diagnostiques et thirapeutiques de l'infertiliti masculine. Seront igalement abordis la privention et la priservation de la fertiliti masculine, ainsi que la prise en charge de l'homme siropositif pour le VIH ou VHC souhaitant concevoir par les techniques d'AMP. Par ailleurs, cet ouvrage dicrira les aspects techniques de l'organisation d'un centre de spermiologie (biologique et clinique), des examens et protocoles thirapeutiques ainsi que leur co{t.