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The investigation of indoor air quality has shown that microbial
contamination is often a problem in buildings. Recent evidence
indicates that fungi are often a part of the picture. A component
of the fungal cell wall, 1 (R)3-ss-glucans not only affect human
health, they are a marker for the existence of fungi in
environmental samples. Toxicology of 1 (R)3-ss-Glucans covers the
basic chemistry and immunobiology of these substances. The authors
begin by introducing current methods for detecting 1
(R)3-ss-glucans in environmental samples and reviewing risk
evaluation in the environment. They go on to discuss numerous
topics including likely occupational and environmental exposure,
studies suggesting a strong link between environmental glucan
concentrations and pulmonary inflammation, and signal transduction
pathways and specific receptors. No other book currently available
brings together the expertise of leading international researchers
to provide a straightforward monograph on the toxicology of 1
(R)3-ss-glucans. It pulls together current knowledge of these
compounds, their effects, measurement, monitoring, and risk
assessment.
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