The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital era of biology. Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design. The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approach an ideal text for senior undergraduate and first-year graduate students.

The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital era of biology. Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design. The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approach an ideal text for senior undergraduate and first-year graduate students.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Master Artificial Tactile Sensing Design for Biomedical Engineering ApplicationsFilled with high-quality photographs and illustrations, including some in color, this definitive guide details the design and manufacturing of artificial tactile systems and their applications in surgical procedures. Artificial Tactile Sensing in Biomedical Engineering explains the fundamentals of the human sense of touch and the latest techniques for artificially replicating it. The book describes the mechanistic principles of static and dynamic tactile sensors and discusses cutting-edge biomedical applications, including minimally invasive surgery, tumor detection, robotic surgery, and surgical simulations. Artificial Tactile Sensing in Biomedical Engineering covers: Capacitive, magnetic, inductive, conductive elastomeric, optical, and thermal sensors Strain gauge and piezoelectric sensors Tactile sensing in surgery and palpation Tactile image information through palpation Tumor detection via artificial tactile sensing Estimating tumor parameters using the finite element method and an artificial neural network Determination of mechanical properties of biological tissues Tactile sensing in remote and robotic surgery Haptics application in surgical simulation