This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology. Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use. The authors are current or former members of the Biometric Research Branch at the National Cancer Institute.  They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools.

This book examines how young people can be re-engaged with schooling and their own learning beyond the school gates. Despite attempts by successive UK governments to promote engagement with education, there has been a substantial increase in formal and informal exclusions from secondary schools, particularly of underperforming students who come from low income families. The book builds on an ethnographic study carried out in a youth centre based on a secondary school site, exploring the social and cultural worlds of fourteen students as they complete a GCSE teamwork assessment. Analysing the 'translation' process of the students as they relocate their understanding of teamwork into the language of assessment, the author posits that student identity is a holistic individual project, where knowledge is produced within the conditions for the production of the self-narrative. This volume calls to educators to recognise the importance of relational pedagogy rooted in social practices, rather than individual cognitive performance. It is sure to be of value and interest to students and scholars of exclusion in education and relational pedagogy, as well as practitioners and policy makers.

We've all heard the arguments that Christianity is irrelevant, irrational and even immoral. But what if the Christian faith makes sense of all that matters? In this thoughtful, engaging book, Simon Edwards challenges the assumptions that may lead us to reject a faith and doubt something that we've never really had the chance to understand in the first place. From our need for meaning and significance, to our desires for truth, goodness, love and hope, he explores the things that matter to us as human beings and shows us why the life, death and resurrection of Jesus Christ might just make sense of them all. The Sanity of Belief is a fresh take on apologetics, faith and doubt, that will leave you with a stronger understanding of Christian belief and how it relates to today's world. It is ideal for anyone looking for a clear, down-to-earth introduction to Christianity, or for those wanting to reaffirm the foundations on which their faith is based.

Written by three surveyors, each with extensive experience in the sector, Dilapidations and Service Charge Disputes will guide practitioners through the common and new practices involved in dealing with disputes on dilapidations and service charge matters. The book offers practical guidance on the related topics of dilapidations and service charge disputes, bridging the gap between heavy-weight legally focussed case law publications and the lighter weight guidance notes. It offers practical and theoretical advice that will be invaluable to any surveyor or solicitor dealing with: condition reports prior to a lease agreement litigation avoidance advice dilapidations law and precedent. Beneficial to surveyors and solicitors acting on behalf of tenants or landlords, this book provides the information and practical advice that can help you improve in your role.

Written by three surveyors, each with extensive experience in the sector, Dilapidations and Service Charge Disputes will guide practitioners through the common and new practices involved in dealing with disputes on dilapidations and service charge matters.

The book offers practical guidance on the related topics of dilapidations and service charge disputes, bridging the gap between heavy-weight legally focussed case law publications and the lighter weight guidance notes. It offers practical and theoretical advice that will be invaluable to any surveyor or solicitor dealing with:

• condition reports prior to a lease agreement
• litigation avoidance advice
• dilapidations law and precedent.

Beneficial to surveyors and solicitors acting on behalf of tenants or landlords, this book provides the information and practical advice that can help you improve in your role.

This book examines how young people can be re-engaged with schooling and their own learning beyond the school gates. Despite attempts by successive UK governments to promote engagement with education, there has been a substantial increase in formal and informal exclusions from secondary schools, particularly of underperforming students who come from low income families. The book builds on an ethnographic study carried out in a youth centre based on a secondary school site, exploring the social and cultural worlds of fourteen students as they complete a GCSE teamwork assessment. Analysing the 'translation' process of the students as they relocate their understanding of teamwork into the language of assessment, the author posits that student identity is a holistic individual project, where knowledge is produced within the conditions for the production of the self-narrative. This volume calls to educators to recognise the importance of relational pedagogy rooted in social practices, rather than individual cognitive performance. It is sure to be of value and interest to students and scholars of exclusion in education and relational pedagogy, as well as practitioners and policy makers.

The crime-infested intersection of West Fayette and Monroe Streets is well-known--and cautiously avoided--by most of Baltimore. But this notorious corner's 24-hour open-air drug market provides the economic fuel for a dying neighborhood. David Simon, an award-winning author and crime reporter, and Edward Burns, a 20-year veteran of the urban drug war, tell the chilling story of this desolate crossroad.

Through the eyes of one broken family--two drug-addicted adults and their smart, vulnerable 15-year-old son, DeAndre McCollough, Simon and Burns examine the sinister realities of inner cities across the country and unflinchingly assess why law enforcement policies, moral crusades, and the welfare system have accomplished so little. This extraordinary book is a crucial look at the price of the drug culture and the poignant scenes of hope, caring, and love that astonishingly rise in the midst of a place America has abandoned.

The notorious corner of West Fayette and Monroe Streets in Baltimore is a 24-hour open-air drug market that provides the economic fuel for a dying neighbourhood. Through the eyes of one broken family - two drug-addicted adults and their smart, vulnerable fifteen-year-old son, DeAndre McCollough - Simon and Burns examine the sinister realities of inner cities across the USA and unflinchingly assess why law enforcement policies, moral crusades and the welfare system have accomplished so little.