Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

Introduction to World Politics: Prospects and Challenges for the United States provides readers the means to understand, grow, and engage in upper-division World Politics. The text encourages students to not just read, but engage with the material which in return will increase enjoyment of, and apparition for, the discipline. Introduction to World Politics: Prospects and Challenges for the United States: Features a succinct approach to the discipline. Unlike other books for ""introductory"" courses, the authors don't 'cram' too much content and detail into their reading. Rather, they cut to the main points which they find essential for make since of how the world works. Challenges readers to not fear the word 'theory', but rather the authors take readers on a methodical journey through the development and application of three central theories. Educates readers on foreign policy challenges faced by the United States such as international security, international organizations, and law and international economics.