Product Design and Development Handbook: An Innovative, Entrepreneurial, and Structured Approach for Engineering Capstone and Industry Projects enables engineering students and practicing engineers to conduct successful product design and development projects. The text uses the Phased Product Development (PPD) process, which was developed by the authors and features two key elements: mini milestones that keep project design and development teams on schedule and within budget; and the use of phase exit checklists that ensure the team demonstrates evidence of meeting all Accreditation Board for Engineering and Technology (ABET) and entrepreneurial mindset (EM) outcomes. The book is divided into 44 modules that align with a two-semester capstone product development course or can be tailored to support a one-semester course. Each module includes pre- and post-class session assignments that break the development process into mini-milestones. An example project-the design and development of a travel iron-is provided to help teams understand how the information in the text can be applied to an actual project. In addition to covering design, this handbook also addresses the important tasks of manufacturing, developing, and validating an engineering prototype. It integrates product engineering into the overall commercialization process. The attributes of "thinking like an engineer" and meeting the sponsor's expectations are emphasized throughout the book and paired with industry examples. The role of the engineering team in the overall product development effort is addressed using the Goldsmith Commercialization Model. The entrepreneurial mindset is integrated into each development phase and the Arizona State University (ASU) Fulton Schools of Engineering (FSE) EM@FSE 2.0 indicators are included in the phase exit checklists. Product Design and Development Handbook is applicable to single discipline, multi-discipline, and trans-discipline team-based product design and development projects and programs. Though the handbook uses mechanical engineering projects as a baseline, it can support all engineering disciplines.