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This book overviews cancer immunity from broad scientific fields,
based on the concept that cancer is a sort of by-product of
infection, inflammation, and host immune response. The innate and
acquired arms of the immune system mainly participate in tumor
immune surveillance, and their activation is critically modulated
by the situation of the tumor microenvironment. Many types of
immune cells join the formation of the microenvironment. In
particular, macrophages and dendritic cells enter the tumor mass to
be main players in the inflammatory milieu of tumors. After
introducing these topics, the book discusses immunotherapy for
cancer patients as an outgrowth of this concept of infection and
inflammation. With the contributions of leading scientists actively
involved in the field of antitumor immunity study, this book
encourages readers to understand the mechanism of general cancers
based on inflammation and will facilitate prevention and the
development of therapeutics for cancer.
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