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Glycosaminoglycans: Chemistry and Biology emphasizes several areas
of glycosaminoglycan research especially analysis and application
of GAGs using a variety of approaches. Chapters focus on chemical
and enzymatic synthesis of GAGs for therapeutic purposes;
biophysical and biochemical methods for studying GAG-protein
interactions; molecular approaches for modulating and defining GAG
biosynthesis; informatics approaches for deciphering GAG code;
computational approaches for establishing specific and/or
non-specific interactions and genetic and biochemical tools for
manipulating/visualizing glycosaminoglycan expression and studying
their functions in a variety of model organisms. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols and key tips on troubleshooting
and avoiding known pitfalls. Authoritative and practical,
Glycosaminoglycans: Chemistry and Biology serves as a valuable
manual for cutting edge methodologies and practical tips to
overcome any obstacles with experimentation pertaining to chemistry
and biology of glycosaminoglycans.
Glycosaminoglycans: Chemistry and Biology emphasizes several areas
of glycosaminoglycan research especially analysis and application
of GAGs using a variety of approaches. Chapters focus on chemical
and enzymatic synthesis of GAGs for therapeutic purposes;
biophysical and biochemical methods for studying GAG-protein
interactions; molecular approaches for modulating and defining GAG
biosynthesis; informatics approaches for deciphering GAG code;
computational approaches for establishing specific and/or
non-specific interactions and genetic and biochemical tools for
manipulating/visualizing glycosaminoglycan expression and studying
their functions in a variety of model organisms. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols and key tips on troubleshooting
and avoiding known pitfalls. Authoritative and practical,
Glycosaminoglycans: Chemistry and Biology serves as a valuable
manual for cutting edge methodologies and practical tips to
overcome any obstacles with experimentation pertaining to chemistry
and biology of glycosaminoglycans.
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