This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.

Digital transformation is a revolutionary technology that will play a vital role in major industries, including global governments. These administrations are taking the initiative to incorporate digital programs with their objective being to provide digital infrastructure as a basic utility for every citizen, provide on demand services with superior governance, and empower their citizens digitally. However, security and privacy are major barriers in adopting these mechanisms, as organizations and individuals are concerned about their private and financial data. Impact of Digital Transformation on Security Policies and Standards is an essential research book that examines the policies, standards, and mechanisms for security in all types of digital applications and focuses on blockchain and its imminent impact on financial services in supporting smart government, along with bitcoin and the future of digital payments. Highlighting topics such as cryptography, privacy management, and e-government, this book is ideal for security analysts, data scientists, academicians, policymakers, security professionals, IT professionals, government officials, finance professionals, researchers, and students.

An ideal resource for dental assistants and hygienists, Damatta/Singhal/Jennings' MEDICAL EMERGENCIES GUIDE FOR DENTAL AUXILIARIES, 5th Edition, delivers up-to-date information and instruction for effectively handling the most common medical emergencies that may occur in the dental office. It covers basic technical instruction, first-aid techniques, legal concerns, safety procedures, prescription management programs and more. Packed with full-color photos, the text's vibrant new design brings core concepts to life, boosts your comprehension and helps you think critically about key concepts. "Test Your Knowledge" boxes enable you to assess your progress, while case studies give you practice thinking through real-life scenarios you may encounter on the job. "Emergency Basics" boxes outline the sequence of steps for recognizing a medical emergency and provide action points to assist the patient.

This new volume, Real-Life Applications of the Internet of Things: Challenges, Applications, and Advances, provides an overview of the Internet of Things along with its architectures, its vital technologies their uses in our daily life and other domains, and associated challenges. The book also covers some advanced topics where IoT is combined with other emerging technologies, such as blockchain and cloud, which will bring a revolution in the era of IoT. Topics in the volume cover the many powerful features and applications of IoT, such as for weather forecasting, in agriculture, in medical science, in surveillance systems, and much more. The first section of the book covers many of the issues and challenging arising from the Internet of Things. The section explores security challenges, such as attack detection and prevention systems as well as energy efficiency and resource management in IoT. Part II introduces various application areas of IoT, including the uses of smart technology in agricultural management, in healthcare diagnosis and monitoring, and in the financial industry. The third section of the book discusses the integration of IoT with blockchain, cloud, and big data and features some advanced topics. The variety of topics includes surveillance network technology, the shift from television to video streaming apps and the technology involved, using IoT-fog computing for smart healthcare, detection of anomalies in climate conditions, and even detection of illegal wood logging activity. The informative chapters in this volume will shed light on the varied challenges, issues, and advances in IoT technology and culture for scientists and researchers, faculty and students, and industry professionals.

This volume takes the reader on a technological voyage of machine learning advancements, highlighting the systematic changes in algorithms, challenges, and constraints. The technological advancements in the ML arena have transformed and revolutionized several fields, including transportation, agriculture, finance, weather monitoring, and others. This book brings together researchers, authors, industrialists, and academicians to cover a vast selection of topics in ML, starting with the rudiments of machine learning approaches and going on to specific applications in healthcare and industrial automation. The book begins with an overview of the ethics, security and privacy issues, future directions, and challenges in machine learning as well as a systematic review of deep learning techniques and provides an understanding of building generative adversarial networks. Chapters explore predictive data analytics for health issues. The book also adds a macro dimension by highlighting the industrial applications of machine learning, such as in the steel industry, for urban information retrieval, in garbage detection, in measuring air pollution, for stock market predictions, for underwater fish detection, as a fake news predictor, and more.

Rare Isotope Beams (RIBs) are ion beams of exotic radioactive nuclei. The study of these nuclei is key to understanding the limits of nuclear existence, nucleo-synthesis in such violent stellar sites as supernovae and merging neutron stars, and the fundamental symmetries of nature. These nuclei also provide a unique probe to study condensed matter and many of them are potentially new radioisotopes for more effective medical diagnostics and therapy. Rare Isotope Beams: Concepts and Techniques gives an up-to-date overview of all these aspects of RIB science in a single volume containing the scientific motivation, production techniques, experimental techniques for studying exotic nuclei, methods used in condensed matter research, and medical applications. The emphasis throughout is on concepts to facilitate understanding of the essence of each topic in this diverse and cross-disciplinary field involving nuclear physics, astrophysics, and particle accelerators. A brief description of major RIB facilities is also presented. Exotic nuclei are difficult to produce in enough numbers and their production involves different nuclear reaction routes and a wide range of advanced technologies, which are presented in a comprehensive manner. Experimental techniques used to study exotic nuclei are provided with examples highlighting the intricate nature of such experiments. Another unique feature is the open-ended nature of the discussions, bringing out the future challenges and possibilities in this evolving field. The book offers an excellent overview of concepts and techniques involved in RIB science for new researchers entering the field as well as professionals.

Packed with step-by-step instructions and practical examples, Singhal/Kantz/Phinney/Halstead's DENTAL ASSISTING: A COMPREHENSIVE APPROACH, 6th Edition, is a one-stop resource for dental assistants in training. This all-inclusive text and product suite for dental assisting programs is written to encompass CODA accreditation standards and DANB certification competencies. Thoroughly updated, content covers basic and advanced clinical skills along with the latest information on key practices and procedures, equipment, and patient and employee safety standards. Icons highlight topics related to infection control, safety and legal issues, while Patient Dialogue, Documentation and Profession Encounters features give students insights into real-world practice. MindTap personalizes learning for students through multimedia and digital tools while equipping instructors with unrivaled support.

This work combines an empirical analysis of productive efficiency change in Newly Industrializing Countries with a theoretical growth model that explores the implications of improvements in productive efficiency on the growth rate of an economy.

This book is a well organised treatise on identification and measurement of dioxins and furan in the environment. It focuses on their source, fate, behaviour, analytical techniques for measurement, and removal/control methods. Although there are numerous publications that address this subject, rarely are prevention and control concepts considered together in a single volume. This book provides a tool for today's environmental researchers by focusing on an integrated approach to managing environmental pollution problems due to dioxins and furans. The overall objective of this book is not simply to provide a general reference, but to serve as a resource for developing approaches to managing environmental pollution problems due to dioxins and furans.

In today’s highly competitive world where digitalization has become need of the hour, companies struggle to carry out digital transformation in the most efficient manner. Process mining is one of the techniques which enable proficient digital transformation and is gaining importance. Companies aspiring to implement process mining and profit from its benefits lack a step-by-step guide covering holistic view to judge the feasibility of process mining within their organization. Therefore, this book focuses on preparing a business case template covering an integrated holistic concept specific to process mining. The aim is to evaluate a feasibility check for organizations that are willing to implement process mining in procurement process. The business case focusses on three aspects: how to execute technical feasibility check, data quality analysis and a financial case. The author discovered that it was extremely vital to carry out process mining readiness check before taking decision to implement it, to enable organized decision and avoid financial losses resulting from failed implementation. Thus, the business case blueprint will provide companies a step-by-step guide to prepare organizations and explore the limitless potential of process mining as a tool. This could be seen as a stepping-stone towards achieving a resourceful and effective digital transformation to prepare for the future.

Series Information:
Garland Studies on Industrial Productivity

The townsfolk believe there is a monster in the forest. Reema bravely goes to investigate. Using the world's largest known database of writing for and by children, our experts have defined 300 ambitious words to help children succeed at school. We've combined these with fully-decodable books that help you match your phonics teaching and practice, while inspiring and engaging your young readers. Specially developed to enhance children's vocabulary alongside their decoding skills, these books are perfect for sharing.

It's not just animals that can become endangered. Find out more about the world's most interesting endangered plants. Using the world's largest known database of writing for and by children, our experts have defined 300 ambitious words to help children succeed at school. We've combined these with finelly levelled books that help you develop support comprehension and fluency, while inspiring and engaging your young readers.

Engaging fiction and non-fiction fully aligned to each week of Essential Letters and Sounds, allowing children to consolidate their phonic knowledge through reading in context. These fully decodable readers are 100% matched to the phonic progression of Essential Letters and Sounds. Essential Letters and Sounds is a systematic synthetic phonics programme validated by the Department for Education. These readers complement your existing decodable readers from Oxford University Press and can be used alongside them to support the teaching of Essential Letters and Sounds. Fun with Nan and Pop! allows children to apply their phonics learning from Reception, Autumn 2, Week 3 of Essential Letters and Sounds.

Engaging fiction and non-fiction fully aligned to each week of Essential Letters and Sounds, allowing children to consolidate their phonic knowledge through reading in context. These fully decodable readers are 100% matched to the phonic progression of Essential Letters and Sounds. Essential Letters and Sounds is a systematic synthetic phonics programme validated by the Department for Education. These readers complement your existing decodable readers from Oxford University Press and can be used alongside them to support the teaching of Essential Letters and Sounds. Get Fit! allows children to apply their phonics learning from Reception, Summer 1, Week 2 of Essential Letters and Sounds.

Engaging fiction and non-fiction fully aligned to each week of Essential Letters and Sounds, allowing children to consolidate their phonic knowledge through reading in context. These fully decodable readers are 100% matched to the phonic progression of Essential Letters and Sounds. Essential Letters and Sounds is a systematic synthetic phonics programme validated by the Department for Education. These readers complement your existing decodable readers from Oxford University Press and can be used alongside them to support the teaching of Essential Letters and Sounds. Helping Out allows children to apply their phonics learning from Year 1 , Autumn 2, Week 1 of Essential Letters and Sounds.