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Natural Products and Drug Discovery: An Integrated Approach
provides an applied overview of the field, from traditional
medicinal targets, to cutting-edge molecular techniques. Natural
products have always been of key importance to drug discovery, but
as modern techniques and technologies have allowed researchers to
identify, isolate, extract and synthesize their active compounds in
new ways, they are once again coming to the forefront of drug
discovery. Combining the potential of traditional medicine with the
refinement of modern chemical technology, the use of natural
products as the basis for drugs can help in the development of more
environmentally sound, economical, and effective drug discovery
processes. Natural Products & Drug Discovery: An Integrated
Approach reflects on the current changes in this field, giving
context to the current shift and using supportive case studies to
highlight the challenges and successes faced by researchers in
integrating traditional medicinal sources with modern chemical
technologies. It therefore acts as a useful reference to medicinal
chemists, phytochemists, biochemists, pharma R&D professionals,
and drug discovery students and researchers.
Essentials of Botanical Extraction: Principles and Applications
provides a unique, single source of valuable information on the
various botanical extraction methods available, from conventional
to the use of green and modern extraction technologies including
ultrasounds, microwaves, pressurized liquids, and supercritical
fluids. Most extracts obtained from botanicals are often poorly
characterized with unidentified active or inactive constituents. A
wise selection of an extraction strategy is vital to drug discovery
from medicinal plants as extraction forms the basic first step in
medicinal plant research. This book also explores the mathematical
hypotheses and innovations in botanical extractions and analyzes
different post extraction operations so that dependency on
serendipity is reduced and the same be converted into programmed
drug discovery.
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