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Showing 1 - 4 of 4 matches in All Departments
Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers.
Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery.
Lactic acid bacteria (LAB ) produce different types of antimicrobial compounds that can be used in controlling food and feed spoilage . Bacteriocin, one search ribosomally synthesized proteinaceous antimicrobial compound, acts against the closely related bacteria by 'all or none ' mechanism And Thus have least Possibility of resistance development against the bacteriocins . One mostly widely used bacteriocin in food preservation is nisin produced by several species of Lactococcus spp. and trials of other bacteriocins Like pediocin, Helveticin, Enterocins, Piscicolins, Leucocins etc are so being done for effective biopreservatives. Apart from bacteriocins production LAB Thus produce different types of antifungal compounds Which may Therefore be used as to alternative to food and feed preservatives against certain food spoilage fungal strains .
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