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Polycystic ovarian disease, or polyfollicular ovarian disease, as
Dr. Fut terweit prefers to call it, is a disease of uncertain
etiology and for which numerous modes of therapy have been
advanced. Understanding of its pathophysiology should shed light on
factors regulating normal ovarian function; the converse is also
true. Recent years have brought about great understanding of the
neuro endocrine regulation of gonadal function, as well as of
factors in the microenvironment of the ovary which affect its
function. It is also ap preciated that cases classified as
polycystic ovarian disease actually rep resent a clinical and
pathological spectrum which may reflect the effects of diverse
etiological factors. In the present volume, Dr. Futterweit presents
the fruits of his long interest in and extensive experience with
this disease. He thoroughly and thoughtfully reviews the vast
amount of basic and clinical information that has been garnered
with regard to this condition over the past decade. The numerous
theories that have been advanced to explain its etiology are
presented in balanced fashion, in addition to a hypothesis, which
is well formulated and amenable to clinical testing. His clinical
interests and judgment are well represented by his presentation of
the diverse manifestations of this condition, the approach to
proper diagnosis, and the available therapeutic options. Patients
with this disease represent diagnostic and therapeutic prob lems in
a situation where manifestations of disease may lead to major
emotional stress."
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