This book constitutes the refereed proceedings of the 10th International Conference on Knowledge Science, Engineering and Management, KSEM 2017, held in Melbourne, Australia, in August 2017. The 35 revised full papers and 12 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: text mining and document analysis; formal semantics and fuzzy logic; knowledge management; knowledge integration; knowledge retrieval; recommendation algorithms and systems; knowledge engineering; and knowledge representation and reasoning.