This volume is a unique combination of papers that cover critical topics in biostatistics from academic, government, and industry perspectives. The 6 sections cover Bayesian methods in biomedical research; Diagnostic medicine and classification; Innovative Clinical Trials Design; Modelling and Data Analysis; Personalized Medicine; and Statistical Genomics. The real world applications are in clinical trials, diagnostic medicine and genetics. The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS). The conference was held in Bethesda in June 2013, and the material has been subsequently edited and expanded to cover the most recent developments.

Demands on the construction industry are changing, and it is now virtually essential for environmental management to be considered at all stages of a project. Many construction managers are finding a quantitative approach useful, and this book outlines four quantitative methods which can be applied at different construction stages, and which fit within a comprehensive framework of dynamic Environmental Impact Assessment (EIA). These include: a method to quantitatively evaluate and reduce pollution and hazards levels a method to evaluate the environmental-consciousness of proposed construction plans a method to reduce on-site construction wastes through an incentive reward programme a method to promote C and D waste exchange in the local construction industry. With an experimental case study of the application of these methods, this book delivers a comprehensive review of environmental management issues in construction. With regulatory requirements potentially favouring the quantitative approach, this timely guide ensures that contractors will be able to keep pace with environmental management standards.

This unique professional volume is about the recent advances in the lattice Boltzmann method (LBM). It introduces a new methodology, namely the simplified and highly stable lattice Boltzmann method (SHSLBM), for constructing numerical schemes within the lattice Boltzmann framework. Through rigorous mathematical derivations and abundant numerical validations, the SHSLBM is found to outperform the conventional LBM in terms of memory cost, boundary treatment and numerical stability.This must-have title provides every necessary detail of the SHSLBM and sample codes for implementation. It is a useful handbook for scholars, researchers, professionals and students who are keen to learn, employ and further develop this novel numerical method.

This book aims to serve as a practical guide for novices to design and conduct measurements of thermal properties at the nanoscale using electrothermal techniques. An outgrowth of the authorsaEURO (TM) tutorials for new graduate students in their own labs, it includes practical details on measurement design and selection, sensitivity and uncertainty analysis, and pitfalls and verifications. The information is particularly helpful for someone setting up their own experiment for the first time. The book emphasizes the integration of thermal analysis with practical experimental considerations, in order to design an experiment for best sensitivity and to configure the laboratory instruments accordingly. The focus is on the measurements of thermal conductivity, though thermal diffusivity and thermal boundary resistance (thermal contact resistance) are also briefly covered, and many of the principles can be generalized to other challenging thermal measurements.The reader is only expected to have the basic familiarity with electrical instruments typical of a university graduate in science or engineering, and an acquaintance with the elementary laws of heat transfer by conduction, convection, and radiation.

This book aims to serve as a practical guide for novices to design and conduct measurements of thermal properties at the nanoscale using electrothermal techniques. An outgrowth of the authorsaEURO (TM) tutorials for new graduate students in their own labs, it includes practical details on measurement design and selection, sensitivity and uncertainty analysis, and pitfalls and verifications. The information is particularly helpful for someone setting up their own experiment for the first time. The book emphasizes the integration of thermal analysis with practical experimental considerations, in order to design an experiment for best sensitivity and to configure the laboratory instruments accordingly. The focus is on the measurements of thermal conductivity, though thermal diffusivity and thermal boundary resistance (thermal contact resistance) are also briefly covered, and many of the principles can be generalized to other challenging thermal measurements.The reader is only expected to have the basic familiarity with electrical instruments typical of a university graduate in science or engineering, and an acquaintance with the elementary laws of heat transfer by conduction, convection, and radiation.

As the construction industry changes the need for the effective incorporation of environmental considerations has become widely accepted. It is now being enforced effectively in many countries. Large numbers of construction managers can find value in adopting quantitative approach to environmental management, and this book outlines an integrative methodology for applying knowledge-based dynamic environmental impact assessment in construction.
Four quantitative methods are presented for the application of the techniques at different construction stages, fitting within a comprehensive framework of dynamic Environmental Impact Assessment (EIA). These are a method to quantitatively evaluate and reduce pollution and hazards levels, a method to evaluate the environmental-consciousness of proposed construction plans and select the best one, a method to reduce on-site construction wastes through an incentive reward programme, and a method to promote C&D waste exchange in the local construction industry. Finally, the implementation of the integrative analytical approach is illustrated using an experimental case study.
Contractors should be able to conduct effective, efficient and economical environmental management and achieve their targets in line with governmental laws and regulations, the ISO 14001 environmental management system (EMS), or environmental management standards within their enterprises. Most environmental management tools used at present are qualitative, but potential requirements are quantitative, so this book fills the need.

Providing new knowledge on risk analysis and simulation for megaprojects, this book is essential reading for both academics and practitioners. Its focus is on technical descriptions of a newly developed dynamic systems approach to megaproject risk analysis and simulation. This is backed up by a discussion of the methodology as applied in a comprehensive case study on the Edinburgh Tram Network (ETN) project. The book informs both academic researchers and megaproject stakeholders with the latest information on risk as applied to megaprojects. As well as the complete case study, the book includes a general risk analysis framework for megaprojects, an analytic network process (ANP) method for risk quantification, a system dynamics (SD) method for risk simulation, and practical guides for the application of the dynamic systems approach in megaproject research and practice.

This volume is a unique combination of papers that cover critical topics in biostatistics from academic, government, and industry perspectives. The 6 sections cover Bayesian methods in biomedical research; Diagnostic medicine and classification; Innovative Clinical Trials Design; Modelling and Data Analysis; Personalized Medicine; and Statistical Genomics. The real world applications are in clinical trials, diagnostic medicine and genetics. The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS). The conference was held in Bethesda in June 2013, and the material has been subsequently edited and expanded to cover the most recent developments.

The Material Point Method: A Continuum-Based Particle Method for Extreme Loading Cases systematically introduces the theory, code design, and application of the material point method, covering subjects such as the spatial and temporal discretization of MPM, frequently-used strength models and equations of state of materials, contact algorithms in MPM, adaptive MPM, the hybrid/coupled material point finite element method, object-oriented programming of MPM, and the application of MPM in impact, explosion, and metal forming. Recent progresses are also stated in this monograph, including improvement of efficiency, memory storage, coupling/combination with the finite element method, the contact algorithm, and their application to problems.

Computational fluid dynamics (CFD) has been widely applied in a wide variety of industrial applications, including aeronautics, astronautics, energy, chemical, pharmaceuticals, power and petroleum.This unique compendium documents the recent developments in CFD based on kinetic theories, introducing flux reconstruction strategies of kinetic methods for the simulation of complex incompressible and compressible flows, namely the lattice Boltzmann and the gas kinetic flux solvers (LBFS or GKFS). LBFS and GKFS combine advantages of both Navier-Stokes (N-S) solvers and kinetic solvers.Detailed derivations, evaluations and applications of LBFS and GKFS, and their advantages over conventional flux reconstruction strategies are analyzed and discussed in the volume.The must-have reference text is useful for scholars, researchers, professionals and students who are keen in CFD methods and numerical simulations.