Hysterectomy is the second most common major surgical procedure performed on women in the United States. Because of new nonsurgical treatments and the rising opposition to the procedure from women's and patients' groups, hysterectomies are performed less frequently than in the past, but many disorders of the uterus--fibroid tumors, uterine and cervical cancer, pelvic inflammatory disease, endometriosis, adenomyosis, and uterine prolapse--still may require surgical treatment. For some women, the decision to have a hysterectomy is an easy one; for others, it is a difficult choice associated with concerns about risks, discomfort, and female identity.

In "Hysterectomy: Exploring Your Options," experienced gynecologists Edward Wallach and Esther Eisenberg provide complete and up-to-date information about every aspect of the procedure. Written with compassion for all women, this indispensable guide explains the anatomy of the uterus, describes the symptoms of gynecological disorders that may require hysterectomy, discusses the full range of diagnostic tests and treatments, provides details of the surgery itself and postoperative recovery, includes details about other approaches to treatment, and examines long-term consequences involving sexual and reproductive issues as well as hormone replacement therapy. Also included is useful advice about how to talk with your doctor and case studies illustrating the real-life experiences of a variety of women.

In "Hysterectomy: Exploring Your Options," women will find the information they need to work with their physicians to make informed decisions about their health care.

Offers an expert blend of sound theory and evidence based therapy for residents and practitioners. Provides a clear path through the increasing complexity of ART options and techniques, using clinical experience and common practical sense. Condenses the aspects of knowledge and practice most relevant for learning the practical basics of diagnosis and decision making.

This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients with breast cancer and require an accessible, up-to-date survey of the dynamic treatment landscape.

This book offers a comprehensive roadmap for determining when and how to regulate risky reproductive technologies on behalf of future children. First, it provides three benchmarks for determining whether a reproductive practice is harmful to the children it produces. This framework synthesizes and extends past efforts to make sense of our intuitive, but paradoxical, belief that reproductive choices can be both life-giving and harmful. Next, it recommends a process for reconciling the interests of future children with the reproductive liberty of prospective parents. The author rejects a blanket preference for either parental autonomy or child welfare and proposes instead a case-by-case inquiry that takes into account the nature and magnitude of the proposed restrictions on procreative liberty, the risk of harm to future children, and the context in which the issue arises. Finally, he applies this framework to four past and future medical treatments with above average risk, including cloning and genetic engineering. Drawing lessons from these case studies, Peters criticizes the current lack of regulatory oversight and recommends both more extensive pre-market testing and closer post-market monitoring of new reproductive technologies. His moderate, pragmatic approach will be widely appreciated.

The first complete reference dedicated to the full spectrum of women's imaging topics "Women s imaging" refers to the use of imaging modalities (X-ray, ultrasound, CT scan, and MRI) available for aiding in the diagnosis and care of such female-centric diseases as cancer of the breast, uterus, and ovaries. Currently, there is no single reference source that provides adequate discussions of MRI and its important role in the diagnosis of patients with women's health issues. Thoroughly illustrated with the highest-quality radiographic images available, Women s Imaging: MRI with Multimodality Correlation provides a concise overview of the topic and emphasizes practical image interpretation. It makes clear use of tables and diagrams, and offers careful examination of differential diagnosis with special notes on key learning points. Placing great emphasis on magnetic resonance imaging (MRI), while providing correlations to other important imaging modalities, the comprehensive book features the latest guidelines on imaging screening and includes in-depth chapter coverage of: * Pelvis MRI: Introduction and Technique * Imaging the Vagina and Urethra * Pelvic Floor Imaging * Imaging the Uterus * Imaging the Adnexa * Imaging Maternal Conditions in Pregnancy * Fetal Imaging * Breast MRI: Introduction and Technique * ACR Breast MRI Lexicon and Interpretation * Preoperative Breast Cancer Evaluation and Advanced Breast Cancer Imaging * Postsurgical Breast and Implant Imaging * MR-Guided Breast Interventions Providing up-to-date information on many of the health issues that affect women across the globe, Women's Imaging will appeal to all general radiologists especially those specializing in body imaging, breast imaging, and women s imaging as well as gynaecologists and obstetricians, breast surgeons, oncologists, radiation oncologists, and MRI technologists.

Over the last hundred years, pregnancy and childbirth has become increasingly safe - yet it is still a site of risk, and a contested ground on which health professionals and pregnant women both face high costs of error. In this context, all those involved in managing pregnancy and birth are expected to identify and mitigate risk: pregnant women are subject to increasing surveillance to ensure the safety of the unborn foetus, and every aspect of childbearing is increasingly medicalised. This publication brings together fascinating social science research to explore the ways in which risk is both created and managed in pregnancy and childbirth. The introductory chapters reflect on the changing social context of childbirth, in particular the medicalisation of both pregnancy and childbirth with development of specialist practitioners, such as obstetricians and midwives who claim to have the knowledge, technology and skills to identify and manage the risks involved. The next three chapters that examine the ways in which women's behaviour during pregnancy is constructed as potentially risky -- for example smoking, drinking alcohol and taking drugs, and how these risks are monitored and mitigated. The final two parts of the book address the construction of and responses to both medicalisation and risk in childbirth. Altogether, it represents a valuable insight into the complex world of pregnancy, childbirth and risk. This book brings together editorials and articles originally published in special and open issues of Health, Risk and Society.

Now in its sixth edition, Infectious Diseases in Obstetrics and Gynecology remains the only book to comprehensively cover infectious diseases in both obstetrics and general gynecology. Distilling complex clinical problems into an easy to use format, this text is divided in four unique sections, and some of these topics include:

Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO's cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

Cervical cancer is a major disease worldwide, with 500,000 new cases diagnosed every year. Through aetiological studies, an association has been established with human papilloma virus (HPV) infection throughout the pathological spectrum of this disease. Studies of the molecular and biological basis for the role of HPV in cervical lesions involve clinicians, virologists, cell and molecular biologists, and most recently immunologists. This book is a review of HPV infection in cervical cancer, providing the background to the potential for immunological intervention. Individual chapters have been written so that the reader, irrespective of level or discipline, can follow the text, and each is integrated so that the book as a whole provides a detailed insight into the most relevant scientific issues of HPV and cervical cancer. This book should provide an interface for students, scientists and clinicians with a realistic and critical evaluation of the advances and problems in the implementation of immunologically based prophylactic and therapeutic strategies in HPV-associated disease. This book should be of use to postgraduate students, research scientists and clinicians involved in eith

This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "true" DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer. Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

The midwife's role is examined in the community and family-health context in this handbook on effective maternal and newborn care for midwives and other healthcare providers. The skills, competencies, and knowledge required to make informed decisions about neo- and postnatal care are covered, including anatomy and the physiology of reproduction, high-risk pregnancies, and labor and birth. Theoretical and practical issues illuminate a midwife's role in the prevention of illness in mothers and babies, with attention to the unique challenges of midwifery in developing nations. Insights from current research studies and critical questions about midwife practice will help those new to health care understand the unique challenges of this form of health-service delivery.

This sensible book draws on evidence-based data, provides updated evidence focusing on the impact of pregnancy complications on long-term morbidity of both mother and child and aims to give a clear and comprehensive set of tools for general practitioners counseling women in different stages of their lives. Chapters are contributed by a multidisciplinary team of obstetricians, oncologists, pediatricians, internal medicine specialists, and psychiatrists. The book may serve as a valuable resource for a broad spectrum of clinicians and healthcare professionals. Medical and nursing students as well as residents in family medicine, obstetrics, and pediatrics may derive great benefit from it in various stages of their training.

Genitourinary Imaging - A Case Based Approach is a user friendly, portable guide that offers a comprehensive coverage of the subspecialty with an emphasis on all modalities. As subspecialty practice has become the norm in radiology, it becomes increasingly important to keep abreast of the latest information within the specialty that one is practising. The case based nature of this book, with modality independent content, allows the reader to assimilate practice specific information with ease. Full color images with tabular salient points, imaging algorithms and evidence based criterion support the text. Key points provide succinct explanations of the disease and an appropriate differential diagnosis, as well as providing a brief description of therapy and prognosis. Genitourinary Imaging - A Case Based Approach is aimed at residents and training and practicing genitourinary radiologists.

Endometriosis is one of the most common gynecological diseases, causing pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it. This book provides a clear insight into the pathogenesis and pathophysiology of endometriosis—essential information for clinicians intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.  

Rheumatic (or systemic autoimmune) diseases disproportionately affect young women: the female-to-male ratio for patients with systemic lupus erythematosus during the reproductive years is approximately 9:1. In the mid- to late-twentieth century, women with rheumatic disease diagnoses were often advised to avoid pregnancy due to fear of disease exacerbation and adverse outcome. In more recent years, many women with rheumatic disease have deferred childbearing until a later age due to active disease or unsafe therapies. However, with advances in rheumatology therapies, obstetric monitoring, and reproductive medicine technologies, increasing numbers of women with rheumatic diseases are pursuing pregnancy. As a result, obstetricians and rheumatologists need to be aware of the current state of knowledge and the recommendations for management of pregnancy in these patients. Contraception and Pregnancy in Patients with Rheumatic Disease explains the basics of contraception, fertility treatment, and pregnancy in rheumatic disease patients and serves as a guide and reference tool for both rheumatologists and OB/GYNs. Most general rheumatologists and OB/GYNs have limited experience in caring for rheumatic disease patients during pregnancy, and many do not have ready access to expert colleagues in this area. This book summarizes the current state of knowledge and presents a general approach for assessment of the rheumatic disease patient considering pregnancy, hormonal contraception or infertility treatment.

This volume provides an overview of the research describing the effects of child maltreatment on mental health, cognitive and social-emotional development. It offers descriptions of selected empirically based treatments (EBTs) written by scholars associated with its development, training, or research on its effectiveness. Each contributor presents the theoretical foundation of the EBT and evidence of its efficacy, describes the treatment process and illustrates this process with a case study of its use with a maltreated child, and discusses possible limitations. Following the chapters describing the interventions, the editors address key issues of the dissemination and implementation of these EBTs. They describe the strategies the selected interventions have used to ensure treatment fidelity in training and dissemination from the perspective of implementation science's core components of implementation. The challenges of implementing EBTs, and the difficulty of fitting protocol to the reality of clinical practice in community mental health settings are also discussed. This volume offers a central source of information for students and practitioners who are seeking effective interventions to address problems associated with child maltreatment.

Advances in technology now offer promising solutions to deal with the chronological aging of the cell, tissue or organ to synchronize its existence and its use. This book covers the developments in and benefits of the latest vitrification technology and its extensive applications in reproductive medicine. Protocols of gametes (oocyte and sperm), embryos, blastocysts and ovarian tissue cryopreservation have been reviewed by leaders in the field. In order to address the escalation in cross-border reproductive tourism entailing the transfer of reproductive cells and tissues rather than the patient, the challenges, caution and emerging possibilities of nitrogen vapor shipment of vitrified cells have been discussed. Current perspectives on oocyte banking present the reader with options and solutions to effectively utilize these gametes despite the physiological deterrents.The versatile applications and potential of vitrification of human embryonic stem cells, discussed in the concluding chapter, is an exciting reality offered by vitrification to help overcome numerous stumbling blocks in the management of various disorders.

Constipation: A Practical Approach to Diagnosis and Treatment serves as an unmet resource for physicians and other health care providers, including trainees and students, who see patients with constipation. The text reviews pathophysiologic mechanisms and details evaluation and management strategies. The volume also enables the reader to identify epidemiologic factors and quality of life parameters for patients with constipation, discuss differences in pathophysiologic mechanisms for different etiologies of constipation, recognize primary causes of constipation, and assess special considerations related to the symptom of constipation including presentations in the elderly, in pregnant women, in patients with systemic diseases, and patients with a history of abuse. Written by thought leaders and recognized experts in gastrointestinal motility and medical education, Constipation: A Practical Approach to Diagnosis and Treatment is of great value and utility for gastroenterologists, primary care physicians, gynecologists, nurse practitioners, physician's assistants, as well as fellows and residents.

Ovarian cancer is the most lethal malignancy of the female reproductive system and is also the fifth leading cause of cancer death in women. Sharing common characteristics of cancer, ovarian malignancy possess several clinical and biological particularities In Ovarian Cancer: Methods and Protocols, expert researchers in the field provide methods that have been created or adapted to study various aspects of ovarian cancer. These methods and techniques are applicable to study genetic alterations present in ovarian cancer, structural and metabolic features of ovarian cancer cells, include in vitro and in vivo models that recapitulate ovarian cancer development and progression, and describe ovarian cancer-oriented drug delivery approaches. Methodological chapters are grouped into seven thematic parts, any of them is introduced by short subject review. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Ovarian Cancer: Methods and Protocols seeks to aid scientist to optimize study designs, to correctly select the most applicable methods, and to produce interesting and novel results.

This book offers a unique and focused study of the use of ultrasound during the first trimester, a critical time in a fetus' development. It includes basic examination guidelines as well as cutting-edge ultrasound modalities, including Doppler and three-dimensional ultrasound, for the period immediately preceding conception through early embryology. Beginning with a discussion of the safety and efficacy of diagnostic ultrasound and the use of this modality for the evaluation and treatment of infertility, recognized experts in the field explore conditions that may interfere with normal conception or development, including maternal diseases that would benefit from early scanning, elements of teratology, multiple gestations, ectopic pregnancy, gestational trophoblastic disease, fetal anomalies and invasive procedures in the first trimester. Numerous illustrations and figures are provided to serve as aids for understanding key concepts. First-Trimester Ultrasound is a valuable resource for many, in or after training, in obstetrics and gynecology, radiology, emergency medicine, family medicine and genetics.

Nutrition and Diet in Menopause is a single comprehensive source that will provide readers with an understanding of menopause. Holistic in its approach, this volume is divided into five sections covering psychological, endocrine and lifestyle factors, metabolism and physiology, bone and nutrition, cancer and nutrition, cardiovascular factors and dietary supplements in menopause. In-depth chapters review the potential long term consequences of menopause on the overall health of women, not only at the physical level including hot flushes (flashes) , alterations to the genitourinary system, skin changes, decreased cardiovascular functions, hypertension, headache, back pain, and constipation. Written by international leaders and trendsetters, Nutrition and Diet in Menopause is essential reading for endocrinologists, cardiologists, nutritionists and all health care professionals who are interested in women's health.

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of "omics" approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

This practical manual on sperm analysis presents the diagnostic and therapeutic procedures that are used in andrology laboratories to analyse and assess male infertility. Diagnostic areas include: semen analysis and the biochemical, immunological and microbiological examination of human semen and spermatozoa; computer-aided sperm motility analysis; sperm ultrastructure; and assessment of sperm transport through the female tract and sperm fertilizing ability. The clinical relevance of various diagnostic procedures is also discussed. Therapeutic topics include sperm washing techniques, semen cryopreservation, and insemination procedures. The volume also covers safety in the andrology laboratory, technician training, and quality control. The text is extensively illustrated and will be an invaluable resource to all scientists and technicians who diagnose male infertility. It will also be of interest to researchers working in human gamete biology and reproductive physiology. The detailed methods described in the book are relevant to all hospital, commercial, and university laboratories involved in infertility diagnosis and treatment.

The COPD chart presents a detailed overview of the symptoms and causes of Chronic Obstructive Pulmonary Disorder (COPD). Sections help explain the two related respiratory diseases that constitute COPD - emphysema and chronic bronchitis. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).