South African born-and-raised Hollywood screenwriter Helena Kriel is researching the ancient text of the Kama Sutra for a movie she’s writing. At the same time, she is travelling to India to meet with sages and find answers to the universal challenges of sex and love. While searching for love in her doomed relationships, little does she know she will find her answers in caring for her dying brother, Evan, in South Africa.

Set in the mid-1990s, South Africa is just emerging from the darkness of apartheid and bursting with vibrant chaos. The story zooms in on an intense year in the narrator’s life. It centres around the lively and eccentric South African Kriel family: Maya, the combative but inspired mother; Lexi, the sister recently returned from living in a temple in India; Ross, the younger brother diving with sharks; and Helena, the narrator, herself on a journey to understand love and death. At the heart of the story is Evan, her terminally ill 30-year-old gay brother, who has been keeping his illness a shameful secret. Conscious, sensitive, terrified and trying to hang onto sanity as his world changes, Evan becomes paralysed then finally goes blind as death draws ever closer. But it is Evan who leads the family through the fire.

In living through her brother’s fight to stay alive, the narrator finds herself at the heart of a savage story, one she would not have chosen. How could she know when she set out to India to find ancient solutions to the modern problems of our age that her brother’s approaching death would be her greatest teacher? How could she imagine that dying brings everything to life?

The Year Of Facing Fire is an astoundingly written memoir by one of South Africa’s finest writers. It traverses universal themes including love, death and sex, and finds value in the ordinary and great beauty in the uncertain.

Die oorlewingstog van 'n dapper vrou.

“ ʼn Kale vlakte waar my regterbors eens was. Ek maak my oë toe en laat my brein toe om te proe aan hierdie monumentale ding. Kanker schmanker, besluit ek. Ek is nog net soveel vrou soos voor die operasie. My vroulikheid het toe al die tyd nie in my bors gesit nie. Dit sit in my kop, in my hart, in daardie onmeetbare, onaantasbare iets wat die gees genoem word.”

In hierdie aangrypende boek deel die bekende spanningsverhaalskrywer Madelein Rust die intiemste besonderhede van haar reis met borskanker. Dit is ʼn brutaal eerlike vertelling wat haar belewenis van die siekte met patos en humor uitbeeld. Lesers verkry ʼn eiesoortige blik op die fisieke ervarings van borskankerstryders sowel as die ewig veranderende binnewêreld van dié wat teen die siekte veg.

Kanker schmanker! rus borskankerstryders toe met inligting wat nie altyd geredelik beskikbaar is nie en help hul geliefdes om die reis met kanker beter te verstaan. Dit is ʼn boek van hoop en triomf wat die leser hardop laat huil en laat lag. Dis 'n verhaal vir elkeen van ons wat ʼn stryd van enige aard stry.

Shéri Brynard has reached many remarkable milestones, although she was born with Down Syndrome. She talks about how love and acceptance from her family and friends formed her. She tells of her adventures, her pain and the harsh realities she has to face as an adult with Down Syndrome. Her mother tells the tale of living in Shéri’s shadow, speaking without holding back about her crisis of faith when she heard that her daughter had Down Syndrome. A touching tale.

Ilana and Martin Gerschlowitz are an ordinary middle-class South African family – young, newly married with bright, promising futures. Ilana falls pregnant and gives birth to David, a happy, healthy baby boy. At 10 months old, David suffers recurring ear infections, and at 11 months old a terrible fever sends him to hospital. David’s behaviour abruptly changes – he no longer looks at his parents, his motor and budding language skills disappear, and the light in his eyes dims. It is the beginning of a journey with autism that few parents would ever want to encounter, and yet a staggering number of children are now diagnosed with autism, and the number of diagnoses rises every year.

Ilana and Martin work tirelessly to understand David’s autism diagnosis, and to search for ways to treat their son. The couple arrange an international autism conference, open a treatment centre for autistic children, and begin outreach programs for underprivileged families dealing with autism.

Ilana falls pregnant again and their third son, Aaron, develops normally. And then the unthinkable happens – at 16 months Aaron develops ear infections and they decide to insert grommets. Immediately after the procedure, they realise that Aaron is not behaving in his usual manner. Within days, it becomes clear that Aaron, too, has developed autism, and their journey begins afresh. Armed with the knowledge gained from years of treating David, the couple set about ensuring that Aaron’s condition is treated swiftly and carefully.

When the world stopped, all hopes rested on finding a vaccine. One team answered the call and were ready to act. But how do you develop a life-saving drug when every second counts and one mistake could be catastrophic?

Married couple and decades-long research partners Ugur Sahin and Özlem Türeci did just that within weeks of the pandemic breaking out. From convincing Big Pharma to support their ambitious project, to navigating political interference from the Trump administration and the European Union, the road to producing the Pfizer/BioNTech vaccine was by no means smooth. But these cutting-edge innovators overcame every obstacle to provide more than two billion doses of the life-saving drug to countries all around the world in record time.

The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age, containing contributions from the fascinating couple themselves, as well as more than 50 scientists, politicians, public health officials, and BioNTech staff.

Shedding a light on the science behind the breakthrough, The Vaccine tells the story of the trailblazers to whom we all owe a debt of gratitude. More suspenseful than a novel, this is a real-life story of an extraordinary race against time to save the world.

In 2011 the world was shocked when the news broke that Joost van der Westhuizen, known for years as the golden boy of South African rugby and a former Springbok captain, had been diagnosed with motor neuron disease (MND).

This rare condition attacks the central nervous system, causing progressive disability. There is no known cure. All who have seen Joost in action will know that he is not one to give up without a fight. His game-changing prowess as a brilliant scrum half is now focused on a battle for survival and, more importantly, on making a difference to the lives of others with the disease. In a race against time, Joost has a dream to fulfil. He says: “In the beginning you go through all the emotions and you ask, ‘Why me?’ It’s quite simple. ‘Why not me?’ If I have to go through this to help future generations, why not me?” His acceptance of his symptoms is equally pragmatic: “One day you can’t move your arm, another day you don’t have speech. Every day you are reborn and you take the day as it comes.”

Glory Game – The Joost van der Westhuizen Story is a compelling narrative of redemption set against the backdrop of an illustrious career in rugby. It is the story of a modern-day warrior forced to face his own human frailty. Joost shows us that beyond ambition, success and fame lies the true wealth of family and friends, and that within a ravaged body the spirit can remain invincible.

This is the story of a race - not against other vaccines or other scientists, but against a deadly and devastating virus.

On 1 January 2020, Sarah Gilbert, Professor of Vaccinology at Oxford University, read an article about four people in China with a strange pneumonia. Within two weeks, she and her team had designed a vaccine against a pathogen that no one had ever seen before. Less than 12 months later, vaccination was rolled out across the world to save millions of lives from Covid-19. In Vaxxers, we hear directly from Professor Gilbert and her colleague Dr Catherine Green as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it.

This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm; they separate fact from fiction; they explain how they made a highly effective vaccine in record time with the eyes of the world watching; and they give us hope for the future.

Vaxxers invites us into the lab to find out how science will save us from this pandemic, and how we can prepare for the inevitable next one.

First published in 1984 and now in its seventh edition, Coovadia's Paediatrics and child health 7e is a comprehensive introductory textbook, highly regarded by academics and students alike.

This tried and tested best-seller is an introduction to paediatrics and child health emphasising a primary care approach from a southern African perspective to enable practitioners to deal effectively with local health problems. The book maintains a problem-based approach to facilitate a full evaluation of the sick child from a holistic perspective.

This is a clinical textbook dealing with the medical diagnosis and treatment of paediatric health issues. The nine parts cover the practice of paediatrics, focusing on associated disorders. The book maintains a problem-based approach to facilitate a full evaluation of the sick child from a holistic perspective. There are chapters devoted to social paediatrics and child health, as well as a comprehensive list of topics dealing with all aspects of childhood disease including oral and dental conditions, and dermatological or specialty surgical conditions.

It's aimed primarily at Bachelor of Medicine, Bachelor of Surgery (MBChB) students studying Paediatrics in their 4th, 5th or 6th year modules. Paediatrics is also incorporated in the Bachelors of Nursing (BCur) programme usually at 3rd and 4th year.

Since the first edition of HIV and AIDS Education, Care and Counselling was published almost 20 years ago, it has become the standard handbook in Africa for thousands of HIV and AIDS practitioners. However, ongoing HIV and AIDS research requires regular revisions to the handbook for it to remain current with developments in prevention and treatment. Consequently, this new edition has been updated with input from two new specialist co-authors. This has strengthened the multicultural and multidisciplinary approach of this edition to Africa's unique challenges.

Oprah Winfrey and renowned brain development and trauma expert, Dr. Bruce Perry, discuss the impact of trauma and adverse experiences and how healing must begin with a shift to asking, “what happened to you?” rather than “what’s wrong with you?”

Through wide-ranging, and often deeply personal conversation, Oprah Winfrey and Dr. Perry explore how what happens to us in early childhood – both good and bad - influences the people we become. They challenge us to shift from focusing on, “What’s wrong with you?” or “Why are you behaving that way?,” to asking, “What happened to you?” This simple change in perspective can open up a new and hopeful understanding for millions about why we do the things we do, why we are the way we are, providing a road map for repairing relationships, overcoming what seems insurmountable, and ultimately living better and more fulfilling lives.

Many of us experience adversity and trauma during childhood that has lasting impact on our physical and emotional health. And as we’re beginning to understand, we are more sensitive to developmental trauma as children than we are as adults. ‘What happened to us’ in childhood is a powerful predictor of our risk for physical and mental health problems down the road, and offers scientific insights in to the patterns of behaviors so many struggle to understand.

A survivor of multiple childhood challenges herself, Oprah Winfrey shares portions of her own harrowing experiences because she understands the vulnerability that comes from facing trauma at a young age. Throughout her career, Oprah has teamed up with Dr. Bruce Perry, one of the world’s leading experts on childhood trauma. He has treated thousands of children, youth, and adults and has been called on for decades to support individuals and communities following high-profile traumatic events. Now, Oprah joins forces with Dr. Perry to marry the power of storytelling with the science and clinical experience to better understand and overcome the effects of trauma.

In conversation throughout the book, the two focus on understanding people, behavior, and ourselves in the context of personal experiences. They remove blame and self-shaming, and open up a space for healing and understanding. It’s a subtle but profound shift in our approach to trauma, and it’s one that allows us to understand our pasts in order to clear a path to our future - opening the door to resilience and healing in a proven, powerful way.

Grounded in the latest brain science and brought to life through compelling narratives, this book shines a light on a much-needed path to recovery – showing us our incredible capacity to transform after adversity.

For those who could read between the lines, the censored news out of China was terrifying. But the president insisted there was nothing to worry about. Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios.

Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19. The characters you will meet in these pages are as fascinating as they are unexpected.

A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.

Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

The gripping and shocking story of three generations of the Sackler family and their roles in the stories of Valium and Oxycontin, by the prize-winning, bestselling author of Say Nothing.

The Sackler name adorns the walls of many storied institutions – Harvard; the Metropolitan Museum of Art; Oxford; the Louvre. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin, a blockbuster painkiller that was a catalyst for the opioid crisis-an international epidemic of drug addiction which has killed nearly half a million people.

In this masterpiece of narrative reporting and writing, Patrick Radden Keefe exhaustively documents the jaw-dropping and ferociously compelling reality. Empire of Pain is the story of a dynasty: a parable of 21st century greed.

Now in its third edition, Pharmacology in Clinical Practice has been updated to ensure it remains up-to-date and relevant.

Particular care has been taken to simplify and clarify difficult concepts by explaining the links between pharmacology and physiology by providing definitions of new concepts, and using plain language for ease of understanding. Fundamental concepts, such as pharmacodynamics and pharmacokinetics, are well covered in a matter that is accessible and clear. Individual chapters cover the various systems of the body.

Updates include:

• A colour plate to illustrate the links between pharmacology and physiology
• Additional information on side-effects, contra-indications and patient education for groups of drugs
• A guide on how to access this information, to assist with exam preparation and nursing practice
• An updated chapter on nursing management of drug preparations and treatment
• An updated chapter on clinical applications
• A chapter on the legal framework for dispensing and prescribing.

A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened.

In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings.

To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code.

The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.

Reverse Your Diabetes provides all the information and support you need to take control of type 2 diabetes and, potentially, to reverse it.

Based on the latest research and proven results, this clear and effective programme outlines the key steps you need to take to turn around your health: watch what you eat, get more active, monitor your progress and commit to change. Written by diabetes expert Dr David Cavan and in association, Reverse Your Diabetes also tackles the myths and misinformation about type 2 diabetes.

This is an essential book that will empower you to take control of your diabetes and maximise your health for good.

The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market.

Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response.

It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed.

A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.

Do you want to feel happier, healthier, and younger? From impaired brain function to poor skin, weakened immunity to premature aging, your gut health affects more than just your digestive system. In fact, keeping it in balance can revolutionize your health and wellbeing. In this ground-breaking book, esteemed gastroenterologist Dr Roshini Raj outlines tried-and-tested methods to improve your gut health, and offers life-changing results. Sharing practical tips, developed over years of practice, Dr Raj covers everything from the food that we should be eating, to the probiotics, vitamins, and medicines that we should be taking. With Gut Renovation you can optimise your gut, renovate your body, and transform your health, for good.

A dairy-free rich chocolate tart that only takes 10 minutes to make? Banana waffles drizzled with maple syrup that are gluten-free? Flaky sausage rolls that are totally plant-based? Gooey nut butter choc pots made without eggs and ready to eat, fresh from the oven, in just 15 minutes? If you have suffered ill health or have food allergies and intolerances and are looking for recipes that can be made in minutes, with instructions you can understand, using ingredients you probably already have and are guaranteed healthy and tasty, then this is the only cookbook you need in your kitchen. Healthy Living James includes 80 delicious recipes, each one gluten-free, dairy-free, egg-free and mainly plant-based (but with easy options to add in meat or fish). Every recipe aims to teach you how easy it is to cook this food, using affordable supermarket ingredients and a couple of pots and pans, even if you have limited time, energy or skill. 'I've created a cookbook to cater for all, no matter your allergies or food choices. No judgement or preaching, just accessible recipes for all to enjoy. That's why I've opened this recipe book up so that you can use whatever flour, milk, cheese, meat or fish you want.' Recipes include: Chocolate Peanut Butter Shake & Take Oats Strawberry Granola Pot Tex-Mex Quinoa Salad Homemade Pot Noodle Mushroom Stroganoff 20-Minute Fish Curry Chickpea & Avocado Smash Burgers Cheesy Gnocchi Bake Meat-Free Ball Marinara Sub Garlic Flatbread Salt & Vinegar Smashed Potatoes 'Healthy Living James is the book that I needed when I was struggling with my health. Ten years ago, I fell seriously ill out of the blue, which left me bed-bound for two years and house-bound for the next four. I knew that food could be an important part of my recovery journey, but I had no idea how to cook and no energy to concentrate on complicated instructions. I was looking for quick, easy and healthy recipes, with just a handful of ingredients and basic steps that even I could follow. I couldn't find anything suitable, so I decided to teach myself.'

Single best answers to 500+ questions covering all of the key exam topics Perfect preparation and practice for the medical oncology SCE and a valuable tool for the FRCR (Oncology) and ESMO exams Produced in partnership with the Association of Cancer Physicians (ACP) Written by senior trainees and consultants and verified by experienced medical oncology consultants in the style of the specialty certificate exam, this collection of 500 single best answers offers an ideal preparation for success. The aim of 500 SBAs for the Medical Oncology Specialty Certificate Exam is to provide an important evidence-based resource for trainees and non-trainees in preparation for the SCE in Medical Oncology. The practice questions enable learners to assess their own knowledge and identify gaps for further learning. Single-best answer (SBA) questions are accompanied with a description of the answer that highlights important trial data, NICE/other national guidelines and resources. The question number and layout closely mirrors that of the SCE blueprint. Topics covered follow the blueprint of the exam closely, and include: Scientific basis of malignancy, Systemic anti-cancer therapy, Acute oncology, Supportive therapies and palliative care, Breast cancer, Upper GI cancer, Colorectal and anal cancer, Lung and thoracic cancer, Gynaecological cancers, Urological and germ cell cancers, Haematological cancers, Skin cancer, Sarcoma. Less common cancers (Head and neck, CNS cancers, Endocrine), Carcinoma of unknown primary, Professional skills and ethics. Make this book the last thing you use before you take the exam.

Two titles from the best selling Oxford Handbook and Emergencies in series are available together in this great value pack. Now in its tenth edition, the Oxford Handbook of Clinical Medicine has been fully revised, with five new authors on the writing team bringing content fresh from the bedside. Each page has been updated to reflect the latest changes in practice and best management, and the chapters on gastroenterology, history and examination, infectious disease, neurology, and radiology have been extensively revised. Unique among medical texts, the Oxford Handbook of Clinical Medicine is a complete and concise guide to the core areas of medicine that also encourages thinking about the world from the patient's perspective, offering a holistic, patient-centred approach. Acutely unwell patients can deteriorate dangerously without timely recognition and intervention. Emergencies in Clinical Medicine provides an easy-to-use guide to the prompt management of common medical emergencies. Designed for rapid use, it explains how to arrive at a differential diagnosis and how to prevent, manage, or treat an emergency. Fully updated to reflect current clinical guidelines, the second edition includes several new topics, from pulmonary oedemas to the overdose patient. Revised to cover the curricula for internal medical training (IMT) and acute care common stem (ACS), this text covers emergencies from both a problem-based and disease-based approach. Cross-referencing between these two sections enables quick reference, with clear, step-by-step instructions and advice on when and who to call for help. With key algorithms for quick reference and easy to follow symbols indicating clinical severity, from life-threatening to minor, Emergencies in Clinical Medicine will help clinical staff managing acutely ill patients in an easy-to-read and portable format.

From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens - both pre-existing ones and those newly identified - emerge and re-emerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what-if anything-can we do to stop them and their fatal march into our countries, our homes, and our bodies?

In How to Survive a Pandemic, Dr. Michael Greger, physician and internationally-recognized expert on public health issues, delves into the origins of some of the deadliest pathogens the world has ever seen. Tracing their evolution from the past until today, Dr. Greger spotlights emerging flu and coronaviruses as he examines where these pathogens originated, as well as the underlying conditions and significant human role that have exacerbated their lethal influence to large, and even global, levels.

As the world grapples with the devastating impact of the novel coronavirus 2019, Dr. Greger reveals not only what we can do to protect ourselves and our loved ones during a pandemic, but also what human society must rectify to reduce the likelihood of even worse catastrophes in the future.