Intrauterine insemination (IUI), also known as artificial insemination, is a fertility treatment that uses a catheter to place washed sperm directly into the uterus. Its aim is to increase the number of sperm reaching the fallopian tubes and subsequently increase the chances of fertilisation (American Pregnancy Association). This book is a step-by-step guide to intrauterine insemination (IUI). Divided into 12 sections, the text begins with detail on counselling, diagnostic work up, and indications of IUI. The following chapters cover ultrasound monitoring of an ART cycle, stimulation protocol, triggering ovulation, and when and how to administer IUI. The book concludes with discussion on complications of IUI, factors affecting success, and sperm preparation. Authored by recognised experts in the field, the text is further enhanced by colour photographs, illustrations and flowcharts. Key points Step-by-step guide to intrauterine insemination (IUI) Covers the complete ART cycle, from initial counselling and work up, to monitoring and procedures, to success factors and complications Highly illustrated with photographs, diagrams and flowcharts Recognised, expert author team

How does a pathologist become interested and develop expertise in testicular and paratesticular neoplasms, which are relatively uncommon? The truth is simple-the opportunity to see many cases. The authors of this 5th Series Fascicle have such expertise and share a remarkable range of cases from their institutions as well as from many pathologists throughout the world who have sent them cases in consultation over the years. This fascicle is rich source of material that will be a great resource for practicing pathologists and pathologists in training.

The increase of emotional stress has disturbing effects on the neurohumoral regulation of metabolic processes, especially in relation to the cardiovascular system, and increases the changes of organisms developing atherosclerosis. This book studies the effects on the cardiovascular system (in IHD patients) caused by emotions of diverse biological qualities (both positive and negative). At the same time, the relationship between these effects on the functional activity of various hormonal systems and the blood coagulation system are studied in order to determine the mechanisms and development of atherosclerotic processes.

Tourette syndrome (TS) is finally recognized as a common neurodevelopmental disorder, and has gained increasingly high social awareness and scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last decade. Likewise, the way clinicians, teachers, social care workers and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this interesting momentum through a comprehensive and up-to-date overview. Tourette Syndrome covers all of the main aspects related to TS, analyzing the complexity of its clinical presentation, the novel viewpoints of causes and mechanisms, the best way to assess TS patients, and the multifaceted and multidisciplinary treatment options. The multidisciplinary and up-to-date content is the main asset of this volume, which represents a useful source of consultation for a wide audience of professionals, all of whom will have access to what is known so far on TS within their particular area of expertise, at the same time being able to expand and update their knowledge in other areas. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source. Also, questions for future research are clearly presented in the volume, providing a summary of the viewpoint of the contributing authors upon where research on TS should be heading. Finally, clinicians and other health professionals will have access at a glance to the main patients' associations and organizations dedicated to TS worldwide, which can facilitate the direct contact with patients.

A simple, go-to guide to treating chronic pain with trigger point therapy for physical therapists, bodyworkers, and patients From the bestselling author of The Concise Book of Trigger Points This pocket-sized guide covers practical information about the trigger points-the painful knots that can form in tissues like muscles and fascia-that are central to addressing acute and chronic pain with massage, bodywork, and physical therapy. Full-color illustrations and charts help practitioners, students, and patients identify trigger points and address referred pain patterns with ease. The first chapter introduces relevant information on fascia and myofascial meridians and provides an overview of trigger point symptoms, classification, and formation. Subsequent chapters are organized by muscle group and feature concise-yet comprehensive-sections on each of the main skeletal muscles and their trigger points. Common conditions, such as headaches and back pain, are explored for all of the muscle groups, including the muscles of the: * Face, head, and neck * Trunk and spine * Shoulder and arm * Forearm and hand * Hip and thigh * Leg and foot Written in clear, accessible language, this essential guide offers a wealth of knowledge to the lay reader, the student, or the practitioner.

Heart failure occurs in almost epidemic proportions, placing a huge burden on both the healthcare system, and sufferers and their families. This can only rise over coming years as the ageing population, particularly in industrialized countries, increasingly suffers from heart failure and its related comorbidities. The care of this group of patients has evolved significantly over recent years as our knowledge and understanding of the pathophysiology of heart failure has developed. It has become evident that supportive care is integral to comprehensive heart failure care, and this book provides an evidence-based overview of heart failure aetiology, its management, and the supportive care required by patients throughout the course of their disease. Supportive Care in Heart Failure integrates the complexities of heart failure care, bridging knowledge bases from cardiology and cardiothoracic surgery, general medicine and palliative care. The book reviews essential information about epidemiology and pathophysiology of heart failure, and evidence-based medical, device, surgical and interdisciplinary management. It addresses the evaluation and management of quality of life, common symptoms and problems associated with heart failure, and the holistic approach to supportive care throughout the course of the illness through the end of life. Prognostication, communication, and ethical decision making are reviewed in detail. Heart failure has traditionally presented a challenge to physicians, as a generally progressive condition with significant symptoms, a poor quality of life, and high mortality. But by applying the principles of palliative medicine, it is possible to offer a supportive care approach that synthesizes the experience of both the heart failure specialist and the palliative care physician, and offers the best possible quality of care to this group of patients.

The book is a comprehensive and practical guide to the students, trainees, practitioners and gynecologic oncology workers about premalignant and malignant condition of the vulva. It covers all the cancers of the vulva, as well as the surgical and medical aspects of vulvar disease.

A surge of clinical and research interest in postpartum mood disturbances has recently lead to a greater understanding of their phenomenology, etiologies, relationships to one another and to psychiatric disorders. Summarizing these recent advances in theory, research, and treatment, "Postpartum Mood Disorders" hypothesizes that the traditional categories of postpartum mood disorders& mdash;postpartum & ldquo;blues,& rdquo; postpartum depression and postpartum psychosis& mdash;are not necessarily on a continuum. Though interrelated in some cases, these categories represent distinct postpartum states, with different phenomenologies, etiologies, predictive factors, and treatments.

Focusing on the biological aspects of puerperal mood disturbance, the book& rsquo;s first section explores how the ubiquitous, mild postpartum mood changes known as & ldquo;baby blues& rdquo; can be caused by the effects of sudden hormonal withdrawal. It further reviews data about how postpartum depression relates to mood changes occurring at other parts of the reproductive cycle, such as menopause; examines the pattern of mood changes across the reproductive cycle in relation to hormonal changes; and describes cultural differences in understanding, conceptualizing and reacting to postpartum mood changes.

Reviewing the clinical features and differential diagnosis of postpartum psychosis, this timely monograph investigates data about whether psychoses of postpartum onset differs from other psychoses in terms of phenomenology, family history and prognosis, and addresses the acute and long-term impact of major postpartum psychiatric disorders on children& mdash;a central question for families andclinicians.

The book& rsquo;s second section covers treatment strategies for postpartum disorders, examining psychotherapeutic modalities as well as pharmacologic and psychosocial interventions, including the role of self-help groups and volunteer networks, and their relationship to professional care systems.

Authored by pioneering clinicians, researchers, and self-help volunteers who have worked with new mothers and their families in dealing with postpartum mood disturbances, "Postpartum Mood Disorders" provides a much-needed, thorough coverage of a highly prevalent, but often misunderstood, subject.

It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.

This volume is the third in a series of succinct, analytical reviews of advances in the psychiatric care of medically ill patients. Like the previous volumes, "Medical-Psychiatric Practice, Volume 3" is designed to continually update the busy clinician on research and practical developments in medical psychiatry.

Under the guidance of an eminent editorial advisory board, this volume addresses several specific clinical problems that require an integrated medical-psychiatric approach to their diagnosis and treatment. It includes an in-depth discussion of psychopharmacokinetics as well as an update on psychopharmacology in medically ill patients.

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Neurodevelopmental Disorders: DSM-5 Selections is crafted around a specific disorder cited in DSM-5. This selection provides a comprehensive overview of the process of diagnosing neurodevelopmental disorders while serving as a reference guide to assist in the diagnosis of individual patients. The disorder-specific resource is an invaluable addition to the DSM-5 collection and an important contribution to the mental health profession. This book contains the critical disorder-specific content from these four titles: * Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) * DSM-5 Clinical Cases* DSM-5 Self-Exam Questions* DSM-5 Guidebook