This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: * Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages * The genetics of Huntington's disease, including new information on its epidemiology discussions of new testing guidelines * Neurobiology, including recent insights into correlations between pathology and symptoms and a new chapter on neuronal circuitry * The molecular biology of Huntington's disease, including new chapters on the normal function of huntingtin, the molecular pathogenesis of Huntington's disease and the peripheral pathology of the disorder, and an extensively updated chapter on its structural biology * An updated description of the comprehensive care for Huntington's disease, featureing a new chapter on preclinical therapeutics and a completely rewritten chapter on the state of the art of experimental therapeutics and clinical trials.

Neurodevelopmental Disorders: DSM-5 Selections is crafted around a specific disorder cited in DSM-5. This selection provides a comprehensive overview of the process of diagnosing neurodevelopmental disorders while serving as a reference guide to assist in the diagnosis of individual patients. The disorder-specific resource is an invaluable addition to the DSM-5 collection and an important contribution to the mental health profession. This book contains the critical disorder-specific content from these four titles: * Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) * DSM-5 Clinical Cases* DSM-5 Self-Exam Questions* DSM-5 Guidebook

Eureka: Cardiovascular Medicine is an innovative book for medical students that fully integrates core science, clinical medicine and surgery. The book benefits from an engaging and authoritative text, written by specialists in the field, and has several key features to help you really understand the subject: Chapter starter questions - to get you thinking about the topic before you start reading Break out boxes which contain essential key knowledge Clinical cases to help you understand the material in a clinical context Unique graphic narratives which are especially useful for visual learners End of chapter answers to the starter questions A final self-assessment chapter of Single Best Answers to really help test and reinforce your knowledge The book starts with the First Principles chapter which clearly explains the key concepts, processes and structures of the cardiovascular system. This is followed by a Clinical Essentials chapter which provides an overview of the symptoms and signs of cardiovascular disease, relevant history and examination techniques, investigations and management options. The Disease-based chapters give concise descriptions of all major disorders, e.g. ischaemic heart disease, hypertension and heart failure, each chapter introduced by engaging clinical cases that feature unique graphic narratives. The Emergencies chapter covers the principles of immediate care in situations such as cardiac arrest and acute MI. An Integrated care chapter discusses strategies for the management of chronic conditions across primary and other care settings Finally, the Self-Assessment chapter comprises 80 multiple choice questions in clinical Single Best Answer format, to thoroughly test your understanding of the subject. The Eureka series of books are designed to be a 'one stop shop': they contain all the key information you need to know to succeed in your studies and pass your exams.

The new edition of this book is a complete guide to the diagnosis and management of paediatric skin disorders. Beginning with an overview of the basics of skin and neonatal dermatoses, each of the following chapters covers a different condition, clearly explaining its epidemiology, signs and symptoms, clinical evaluation and investigation, diagnosis, and management. Comprising more than 500 pages, the fourth edition has been fully revised to include the latest advances in the field. Four new topics have been added to this edition - skin and systemic diseases, psychodermatoses, skin and primary immunodeficiency disorders, and principles of vaccination in immunosuppressed children. The comprehensive text is highly illustrated with more than 1000 clinical photographs, figures and tables. Suggestions for further reading have also been fully updated. Key points Fourth edition of comprehensive guide to diagnosis and management of paediatric skin disorders Fully revised including four new topics Highly illustrated with more than 1000 clinical photographs, figures and tables Previous edition (9789351526322) published in 2015

This book is an account of a study which provided unique information on trends in growth and respiratory health in British children over 25 years, with methodological discussion and other major findings including risk factors for impaired growth, obesity, respiratory disease and the distribution of coronary heart disease factors. The book provides information on trends in growth, height weight for height and subcutaneous arm tissue, and in respiratory health, asthma attacks and related symptoms, in children aged 5 to 11 years, from 1972 to 1994. It provides information on risk factors for impaired growth, obesity and respiratory disease, and on the distribution of risk factors for coronary heart disease in children. The contribution of the National Health and Growth Study extended to topics such as the effects of changes in welfare policy, under-diagnosis and under-treatment of asthma, nocturnal enuresis, disturbed sleep, the impact of passive smoking on the health of children, and the relation of lung function to the child's intra-uterine environment and to passive smoking. The methodological issues in relation to the conduct of the study and analysis of the data are discussed in non-technical language. Each contribution of the study is discussed in relation to current literature, which is fully referenced throughout.

The important aspects of nutrition, drugs and vaccines are explained in a simple manner so that it will be easily understood. Combination of drugs can be dangerous and should be avoided as far as possible. The indications, contraindications, adverse effects of various medicines and vaccines are discussed in detail which will be helpful for the monitoring of patients. Designed for medical students which will help them to understand various facts in nutrition such as positive and negative aspects of nutrition, feeding and various other nutritional factors. Basics of x-rays and radiological features of various clinical conditions are discussed in detail. Indications, contraindications and adverse effects of various medicine and vaccines are discussed in detail. Mnemonics for easy remembrance and recollection.

The discipline of obstetrics and gynaecology, which dates back many centuries, is unique in that care is extended to every stage in a woman's life. More recently there have been significant scientific advancements and technological inventions that have transformed the health and care of women. Essential Gynaecology aims to deliver core knowledge aligned with clinical application for the treatment of relevant gynaecological conditions. Essential Gynaecology is written by various specialists from South African obstetrics and gynaecology departments. Each chapter is written with dedication and has been carefully selected to fulfil curriculum requirements. Topics covered include gynaecological history and examination, contraception, abnormal uterine bleeding, gynaecological infections, benign and malignant gynaecological conditions, infertility, female urinary incontinence and pelvic organ prolapse, menopause, sexual violence against females and termination of pregnancy. In addition to covering basic content, the text also includes colour photos and multiple choice questions for self-assessment. Essential Gynaecology offers fundamental information for the MBChB programme in gynaecology and responds to a need for a defined focus area. It is recommended for medical students, medical officers, associate clinicians, interns, medical practitioners and OB-GYN registrars.

With an aging baby boomer population and life-prolonging medical advances, psychiatrists must brace for an estimated 10 million late-life patients by the year 2020. Geriatric Psychiatry (Review of Psychiatry, Volume 22) outlines current research on this burgeoning patient group, with practice implications for clinicians.

In Geriatric Psychiatry renowned experts review the latest information on etiology, diagnosis, and treatment options, including pharmacological and behavioral therapies, for a range of late-life disorders: - Depression and anxiety disorders -- A look at late-stage depression and anxiety, with specific information on depression that complicates dementia

- Dementia -- Research advances for better understanding of pathophysiology, improved treatment options, and identification of risk factors

- Late-life psychotic disorders -- Treating late-life schizophrenia, posttraumatic stress disorder, and bipolar disorder, as well as comorbidity associated with disorders such as Alzheimer's disease, Parkinson's disease, and others

- Late-life addictions -- Screening, assessment, treatment, compliance issues, and outcomes for patients with prescription drug and alcohol addictions and comorbid conditions

Also included is an overview of the mental health delivery system for older adults today, including trends in federal expenditures, managed care, long-term-care regulatory trends, special concerns for older adults with severe mental illness, and legislative and policy initiatives.

Every psychiatrist who treats adults must prepare for a major increase in older patients. Geriatric Psychiatry serves as a vital update on current knowledge and practice options for improving quality of life in older adults with mental illnesses.

In this new book, leading experts in the field of child and adolescent consultation-liaison psychiatry present a practical guide for mental health professionals consulting in hospitals, schools, and the juvenile justice system. It is designed to aid the psychiatrist or psychologist in becoming an effective case consultant, as well as a practical-minded educator sought by mental health professionals in other disciplines.

"Child and Adolescent Mental Health Consultation in Hospitals, Schools, and Courts" is comprised of three sections, each covering the following subject areas: - Characteristics of each system and the professionals who work in that setting - The logistics of consultation - Typical problems encountered - Suggested interventions

As the coronavirus pandemic swept across the globe in recent months, many countries have had to implement strategies to fight the virus and keep its people safe. These strategies, particularly in the West, have not been as effective at keeping the numbers of infected people as low as the governments would have hoped.

Charles R Stith predicted the trajectory the virus would take as its spread progressed and developed a critical analysis of the western countries’ responses to the pandemic. He specifically focuses on South Africa’s response to the virus as it spearheads the surge of cases on the African continent.

The crisis has far reaching consequences that impacts the most vulnerable people in the country. A recent OXFAM report draws connections between the lockdown, to hunger, to deaths which confirms the statement Stith made at the beginning of the outbreak about how people would die of hunger as they lose their jobs, their ability to provide for their families and access to fresh foods.

Stith wrote this book in real time in response to the growth and spread of the coronavirus and analyses the results of South Africa’s response to it. He gives answers to the questions politicians should have been asking and gives his view of what Africa will require to recover

What do you do when you wake up in your mid-forties and realize you've been living a lie your whole life? Do you tell? Or do you keep it to yourself?

Laura James found out that she was autistic as an adult, after she had forged a career for herself, married twice and raised four children. This book tracks the year of Laura's life after she receives a definitive diagnosis from her doctor, as she learns that 'different' doesn't need to mean 'less' and how there is a place for all of us, and it's never too late to find it.

Laura draws on her professional and personal experiences and reflects on her life in the light of her diagnosis, which for her explains some of her differences; why, as a child, she felt happier spinning in circles than standing still and why she has always found it difficult to work in places with a lot of ambient noise.

Although this is a personal story, the book has a wider focus too, exploring reasons for the lower rate of diagnosed autism in women and a wide range of topics including eating disorders and autism, marriage and motherhood.

Odd Girl Out gives a timely account from a woman negotiating the autistic spectrum, from a poignant and personal perspective.

Bestselling author of the Wheat Belly franchise brings his next big, game changing idea - the human microbiome and the silent epidemic of SIBO - to the mainstream.

Dr Davis has connected the dots between ''gut health'' and many common, modern ailments and complaints. 1 in 3 people have SIBO (small intestinal bacterial overgrowth), which causes a long list of health issues and illnesses; it is a silent and profound epidemic created by the absence of microbial species that our ancestors had even 50-100 years ago, which have been erased by the industrialisation of food and medicine.

Super Gut shares a four-week plan to reprogram your microbiome based on research and techniques that not only gets to the root of many diseases but improves levels of oxytocin (the bonding/happy hormone), brain health and promotes anti-aging and weight loss. Dr Davis provides not just the science and case studies but also more than 40 recipes and solutions. In Super Gut, he ensures readers understand the science, diagnose their gut issues, eradicate them and maintain their long-term health.

It started with a simple question: How can we help them? It became an international movement called NEGU: Never Ever Give Up. When Jessica Joy Rees was diagnosed with an inoperable brain tumor at age 11, she chose to focus not on herself but on bringing joy and hope to other children suffering from cancer. During the ten months she battled cancer, she and her family worked in the "Joy Factory" (originally their garage) making JoyJars (R)-packages filled with toys, games, and love for other kids with cancer. Jessie first handed them out personally at the hospital where she was being treated, but the effort blossomed quickly and there were soon thousands of JoyJars (R) being distributed across the United States and to over fifteen countries. Today, more than 100,000 kids have received JoyJars (R), and they continue shipping each week to kids in over 200 children's hospitals and 175 Ronald McDonald Houses. Jessie lost her battle with cancer in January 2012, but her message lives on in the Jessie Rees Foundation, which has become a beacon of hope for families fighting pediatric cancer. Join the movement at www.negu.org.

Neurostimulation for Epilepsy: Advances, Applications and Opportunities comprehensively reviews the diverse array of neurostimulation technologies currently in use and development for the treatment of epilepsy. The book covers basic research on mechanisms of neurostimulation, technical features of various FDA-approved and investigational devices for neurostimulation, clinical applications and programming considerations of these devices, and emerging insights and research based on data derived from these devices. It provides a contemporary assessment of neurostimulation in epilepsy, one that reveals recent progress in clinical applications and outcomes, fundamental questions that remain unanswered in the field, and future directions and considerations in developing next-generation devices.