How does a pathologist become interested and develop expertise in testicular and paratesticular neoplasms, which are relatively uncommon? The truth is simple-the opportunity to see many cases. The authors of this 5th Series Fascicle have such expertise and share a remarkable range of cases from their institutions as well as from many pathologists throughout the world who have sent them cases in consultation over the years. This fascicle is rich source of material that will be a great resource for practicing pathologists and pathologists in training.

The brains behind the #1 bestselling Carbs & Cals are back! This time with the perfect book for people following a very low-calorie diet, such as the 8-Week Blood Sugar Diet.

FEATURES:

* 75 delicious, easy-to-prepare recipes

* 30 daily meal plans (all 800 cals or less)

* 20 low-calorie snacks

* 330 photos of ingredients to help you plan your own meals and snacks

* Values for carbs, calories, protein, fat, saturated fat, fibre and 5-a-day fruit & veg

* An informative introduction, explaining the scientific evidence behind the blood sugar diet and other very low-calorie diets

CHAPTERS:

* 15 breakfasts

* 5 curries

* 15 salads

* 5 slow cooker dishes

* 5 stir-fries

* 10 soups

* 6 smoothies

* 15 general healthy meals

* 20 snacks

* 54 pages of individual ingredients

Featuring a range of beautifully designed, mouth-watering recipes, scrumptious snacks and 30 helpful daily meal plans, this visual guide helps you meet your calorie allowance. Be inspired! Planning very low-calorie meals has never been easier!

This is part of the bestselling Carbs & Cals series of health books. Check out the other books in the series: SALADS, SOUPS, SMOOTHIES, 5:2 DIET PHOTOS, the award-winning CARB & CALORIE COUNTER and POCKET COUNTER. Available now on Amazon.

The Comatose Patient, Second Edition, is a critical historical overview of the concepts of consciousness and unconsciousness, covering all aspects of coma within 100 detailed case vignettes. This comprehensive text includes principles of neurologic examination of comatose patients as well as instruction of the FOUR Score coma scale, and also discusses landmark legal cases and ethical problems. As the Chair of Division of Critical Care Neurology at Mayo Clinic, Dr. Wijdicks uses his extensive knowledge to discuss a new practical multistep approach to the diagnosis of the comatose patient. Additionally, this edition includes extensive coverage of the interpretation of neuroimaging and its role in daily practice and decision making, as well as management in the emergency room and ICU. Dr. Wijdicks details long-term supportive care and an appropriate approach to communication with family members about end-of-life decision making.

It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.

Ook in Engels beskikbaar: Knowledge Beats Cancer
JY HET KANKER! 'n Ystervuis beklem jou hart wanneer jy die diagnose hoor. Ná die skok en ontkenning kom die vrae: Wat gaan nou met my gebeur? Wat is my oorlewingskans?
In Kennis Klop Kanker word die pasiënt, en enigeen wat meer van kanker wil weet, ingelig oor alle fasette van kanker:
Wat kanker presies is en hoe kanker ontstaan
Die omvangsyfer en suksesse van kankerterapieë
Belangrikheid van dieet, noodsaaklike gereelde ondersoeke en selfondersoeke
Die vele vertakkinge en benaderinge van moderne terapieë
Moderne behandelingsmetodes en prognose van algemene kankers (29 tipes)
Deurbrake in molekulêre biologie met minder newe-effekte
Beenmurgstamseloorplanting
Mediane oorlewingstatistiek
Alternatiewe, komplementerende en integrerende terapieë
Pasiëntondersteuning, herstel ná mastektomie, kanker by jongmense en kinders, goeie pynkontrole, versorging van pasiënte met gevorderde kanker
Ondersteuning deur gemeenskapsorganisasies
Skrywer se persoonlike perspektief oor lyding en geloofsgenesing
DIE OUTEUR: Albert Stegmann Alberts is 'n onkoloog wat 33 jaar lank met kankerpasiënte gewerk het. Hy het gespesialiseer in al die vertakkings van kankerterapie. Hy is die outeur van verskeie internasionale publikasies.

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: * Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages * The genetics of Huntington's disease, including new information on its epidemiology discussions of new testing guidelines * Neurobiology, including recent insights into correlations between pathology and symptoms and a new chapter on neuronal circuitry * The molecular biology of Huntington's disease, including new chapters on the normal function of huntingtin, the molecular pathogenesis of Huntington's disease and the peripheral pathology of the disorder, and an extensively updated chapter on its structural biology * An updated description of the comprehensive care for Huntington's disease, featureing a new chapter on preclinical therapeutics and a completely rewritten chapter on the state of the art of experimental therapeutics and clinical trials.

This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.

This book is an account of a study which provided unique information on trends in growth and respiratory health in British children over 25 years, with methodological discussion and other major findings including risk factors for impaired growth, obesity, respiratory disease and the distribution of coronary heart disease factors. The book provides information on trends in growth, height weight for height and subcutaneous arm tissue, and in respiratory health, asthma attacks and related symptoms, in children aged 5 to 11 years, from 1972 to 1994. It provides information on risk factors for impaired growth, obesity and respiratory disease, and on the distribution of risk factors for coronary heart disease in children. The contribution of the National Health and Growth Study extended to topics such as the effects of changes in welfare policy, under-diagnosis and under-treatment of asthma, nocturnal enuresis, disturbed sleep, the impact of passive smoking on the health of children, and the relation of lung function to the child's intra-uterine environment and to passive smoking. The methodological issues in relation to the conduct of the study and analysis of the data are discussed in non-technical language. Each contribution of the study is discussed in relation to current literature, which is fully referenced throughout.

First principles chapter clearly explains the key concepts, processes and structures of the female reproductive system. Clinical essentials chapters provide an overview of the symptoms and signs of obstetric and gynaecological disease, relevant history and examination techniques, investigations and management options. Disease-based chapters give concise descriptions of all major disorders, e.g. complications of pregnancy, gynaecological tumours and subfertility, each chapter introduced by engaging clinical cases that feature unique graphic narratives. Emergencies chapter covers the principles of immediate care in situations, such as ectopic pregnancy and eclampsia. Integrated care chapter discusses strategies for the management of chronic conditions across primary and other care settings. Self-Assessment - 80 multiple choice questions clinical SBAs.

Eureka: Cardiovascular Medicine is an innovative book for medical students that fully integrates core science, clinical medicine and surgery. The book benefits from an engaging and authoritative text, written by specialists in the field, and has several key features to help you really understand the subject: Chapter starter questions - to get you thinking about the topic before you start reading Break out boxes which contain essential key knowledge Clinical cases to help you understand the material in a clinical context Unique graphic narratives which are especially useful for visual learners End of chapter answers to the starter questions A final self-assessment chapter of Single Best Answers to really help test and reinforce your knowledge The book starts with the First Principles chapter which clearly explains the key concepts, processes and structures of the cardiovascular system. This is followed by a Clinical Essentials chapter which provides an overview of the symptoms and signs of cardiovascular disease, relevant history and examination techniques, investigations and management options. The Disease-based chapters give concise descriptions of all major disorders, e.g. ischaemic heart disease, hypertension and heart failure, each chapter introduced by engaging clinical cases that feature unique graphic narratives. The Emergencies chapter covers the principles of immediate care in situations such as cardiac arrest and acute MI. An Integrated care chapter discusses strategies for the management of chronic conditions across primary and other care settings Finally, the Self-Assessment chapter comprises 80 multiple choice questions in clinical Single Best Answer format, to thoroughly test your understanding of the subject. The Eureka series of books are designed to be a 'one stop shop': they contain all the key information you need to know to succeed in your studies and pass your exams.

Breastfeeding and Human Lactation, Sixth Edition is the ultimate reference for the latest clinical techniques and research findings that direct evidence-based clinical practice and research for lactation consultants and specialists. It contains everything a nurse, lactation consultant, midwife, women's health nurse practitioner, physician assistant, or Ob/Gyn needs to know about lactation care and science. Topics include placing breastfeeding in its historical context, workplace-related issues, anatomical and biological imperatives of lactation, the prenatal and perinatal periods and concerns during the postpartum period, the mother's health, sociocultural issues, and more vital information. With contributions from the foremost experts in the field, this leading resource contains a clear clinical focus with more than 2,000 research studies supporting the clinical recommendations found in the text. Furthermore, the updated Sixth Edition features new and additional case studies, expanded cultural content, inclusion of new regulations and guidelines, information on alternative medicine, and gender inclusive language. Breastfeeding and Human Lactation, Sixth Edition is also an excellent resource to prepare for certification and practice as an International Board Certified Lactation Consultant (R) (IBCLC (R)). The Navigate 2 TestPrep access code included with every new print copy unlocks access to practice and simulated tests, detailed rationales, and powerful data dashboards. Standalone access to Navigate 2 TestPrep is also available (ISBN: 978-1-284-18994-0).

As the coronavirus pandemic swept across the globe in recent months, many countries have had to implement strategies to fight the virus and keep its people safe. These strategies, particularly in the West, have not been as effective at keeping the numbers of infected people as low as the governments would have hoped.

Charles R Stith predicted the trajectory the virus would take as its spread progressed and developed a critical analysis of the western countries’ responses to the pandemic. He specifically focuses on South Africa’s response to the virus as it spearheads the surge of cases on the African continent.

The crisis has far reaching consequences that impacts the most vulnerable people in the country. A recent OXFAM report draws connections between the lockdown, to hunger, to deaths which confirms the statement Stith made at the beginning of the outbreak about how people would die of hunger as they lose their jobs, their ability to provide for their families and access to fresh foods.

Stith wrote this book in real time in response to the growth and spread of the coronavirus and analyses the results of South Africa’s response to it. He gives answers to the questions politicians should have been asking and gives his view of what Africa will require to recover

It started with a simple question: How can we help them? It became an international movement called NEGU: Never Ever Give Up. When Jessica Joy Rees was diagnosed with an inoperable brain tumor at age 11, she chose to focus not on herself but on bringing joy and hope to other children suffering from cancer. During the ten months she battled cancer, she and her family worked in the "Joy Factory" (originally their garage) making JoyJars (R)-packages filled with toys, games, and love for other kids with cancer. Jessie first handed them out personally at the hospital where she was being treated, but the effort blossomed quickly and there were soon thousands of JoyJars (R) being distributed across the United States and to over fifteen countries. Today, more than 100,000 kids have received JoyJars (R), and they continue shipping each week to kids in over 200 children's hospitals and 175 Ronald McDonald Houses. Jessie lost her battle with cancer in January 2012, but her message lives on in the Jessie Rees Foundation, which has become a beacon of hope for families fighting pediatric cancer. Join the movement at www.negu.org.