The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors. Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders.

Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases. Here is the first reference focusing on these novel drug development opportunities. Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.

Prestigious authorship from USA and Australia Over 100 video clips demonstrate clinical techniques and symptoms and signs of neurological conditions Extensively illustrated with clear line diagrams for ready reference Tips, clinical pearls and management are highlighted Text is logical, systematic and provides a step-by-step approach

Management, Organization and Childbirth: Towards a New Model for the Birth Path explores the complex topic of the birth path with a multidisciplinary magnifying glass on the paradigms, languages, and tools critical to the organization, management, and clinical science. The work consists of five chapters. The first chapter provides a multidimensional analysis of childbirth. The second chapter presents an organizational analysis that moves in unison with different models of health. The third chapter studies the birth path in organizational and cynical terms by describing it in its core processes. The fourth chapter proposes a study conducted in the Italian context, which identifies some useful determinants for redesigning the birth path. The fifth chapter formulates a proposal for redesigning the birth path based on a new health paradigm. The proposed model offers useful insights for multiple categories of readers. To students of medicine and higher education tracks in healthcare management, it can offer opportunities to raise awareness not only regarding multi-professional practice but also regarding confrontation with complementary disciplines. To practitioners and policy makers, it can provide useful stimuli to promote rational and informed decisions around the childbirth. To researchers studying the health context within different disciplinary domains, the model can offer unexplored research spaces within the new business complex system.

The second edition of this textbook builds on the success of the original version by incorporating the latest developments in the clinical evidence base for cardiac rehabilitation whilst also aligning with the wider agenda in terms of commissioning and other national guidance. This edition also recognises the importance of an integrated approach to the prevention and rehabilitation of cardiovascular disease forming the foundation of every cardiac rehabilitation programme. Seven specified standards together with seven core components are presented which aim to ensure programmes are clinically effective and achieve sustainable health outcomes. Edited and written by a multidisciplinary team of experts on behalf of the British Association for Cardiovascular Prevention and Rehabilitation, this book provides contemporary evidence-based guidelines for standards of good practice. Special features: * An evidence-based, practical how to of the subject * Edited and written by the writing group for the BACPR 2012 Standards * With contributions from nationally and internationally recognised experts in this field

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.

Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function of hormones from basic biology to clinical use, offering a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors, signaling pathways, and the biological activities they regulate. The book's stellar editorial board, affiliated with the Japan Society for Comparative Endocrinology, brings together authors that present a compelling structure of each hormone with a consistent presentation that provides a primer surrounding the plethora of hormones that now exist. Comparative endocrinology continues to rapidly expand and new information about hormones is being produced almost daily, making it important to stay up-to-date. Hormone, paracrine, and autocrine factors have been identified as key players in a range of different systems, including immune, musculoskeletal and cardiovascular. Frontiers between disciplines are being blurred and many scientists in fields other than endocrinology are interested in hormones. Scientists now have the unprecedented opportunity to look from invertebrates to vertebrate and identify novel regulatory factors and understand their function and how they determine an organism's physiology and survival.

Autism affects not only the autistic person, but also everyone with whom they come into contact. Families can face a long and often bewildering journey from the moment they notice the first possible signs of autism. As the father of an autistic child himself, Cavan Wood combines real-life stories with clear information to help parents better understand autism and support their child through diagnosis and the social contexts they will encounter through life. Entertaining Angels also shows how schools, workplaces and churches can become friendlier places for autistic people. Recognising that all people are made in the image of God, Cavan Wood offers practical tips on creating inclusive and transformative communities where all are valued and welcomed. Content Benefits: Cavan Wood distils autism information in an accessible way that will help support families facing a diagnosis, and encourages the wider community to be more welcoming to those on the autism spectrum. Provides helpful information to better understand autism * Helps parents recognise signs on the autism spectrum * Helpful tips on navigating home life, school and the workplace * Includes personal stories of real-life experiences * Questions for reflection are included * Frames autism within a Christian context * Shares a practical vision for creating autism-friendly churches * Suitable for parents wanting information and help on autism * Helpful for friends and families who want to support a loved one with autism * Useful for school leaders, employers and church leaders who want to be more accommodating to the needs of autistic people * Content advice provided by an autism charity

Mindfulness in the Birth Sphere draws together and critically appraises a raft of emerging research around mindfulness in healthcare, looking especially at its relevance to pregnancy and childbirth. Divided into three parts, this reflective book: * Investigates the phenomena of mindfulness through discussions of neuroscience, an indigenous worldview and research methods. * Develops the concept of mindfulness for use in practice with women/and babies across the continuum of childbirth. It includes chapters on birth environments, intrapartum care, mental health, fertility, breastfeeding and parenting among others. * Explores mindfulness as a tool for birth practitioners and educators, promoting self-care, resilience and compassion. Each chapter discusses specific research, evidence and experiences of mindfulness, including practical advice and an example of a mindfulness practice. This is an essential read for all those interested in mindfulness in connection to pregnancy and childbirth, including midwives, doulas, doctors and birth activists, whether involved in practice, research or education.

This book describes an intervention model for children with Autism, targeting to act as a guide for parents with children with special needs. As parents play an important role in their child's lives, it is crucial that they are guided and trained to work with and interact with their child. The framework for intervention in this book is named Comprehensive Model for Early Intervention (CMEI), which is an amalgamation of various evidence-based interventions for children with Autism. In this book, four stages of intervention are described in detail, each targeting different stages of development of the child. The four stages of intervention are home-based ABA therapy, small group intervention, school shadow support, and social skills intervention.

Carbs & Cals (Edicao Portuguesa) has been produced especially for the Portuguese market and contains over 900 photos of popular Portuguese food and drink items, with the carbohydrate and calorie values clearly displayed above each photo. The 13-page introduction to the book explains the effect of carbohydrate on blood sugar levels and explores the amount of calories we need in our diet, giving practical tips on how to use the book for diabetes control and weight management. The 151 pages of photographs are arranged into 14 colour-coded sections: Breakfast, Bread, Biscuits & Crackers, Cakes & Pastries, Meals, Meat & Fish Products, Potatoes, Rice & Pasta, Vegetables, Drinks, Fruit, Sweets & Desserts, Snacks, and Take-away Food. There are up to 6 different portion photos for each food, with their corresponding carbohydrate and calorie values displayed above each photo. This provides users with an easy comparison to the food on their plate and a helpful guide to the carbohydrate and calories they are consuming. The prepared/cooked weight is also shown below each photo. Carbohydrate counting is an important part of diabetes management, particularly for Type 1 diabetes, and this book is an invaluable support tool for anyone engaged in this process. For people with Type 2 diabetes or those trying to lose weight, Carbs & Cals vastly simplifies the calorie counting process. It takes out the guesswork and time spent weighing food by showing the calorie content in each food photograph. This allows the user to make choices on how to reduce calories by selecting a smaller portion or by swapping a high calorie snack for a healthier option. Carbs & Cals (Edicao Portuguesa) is in association with APDP (Associacao Protectora dos Diabeticos de Portugal).

Encyclopedia of Infection and Immunity, Four Volume Set provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases. More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential.

You could be forgiven for thinking that the keto lifestyle is an expensive one - but that doesn't have to be the case. In this highly anticipated follow-up to the bestselling Keto Kitchen and Lazy Keto Kitchen, Monya Kilian Palmer shares all the secrets of how to enjoy the energy-boosting (and weight-loss) benefits of the low-carb keto lifestyle without breaking the bank. From clever use of leftovers to how to get the most out of more affordable cuts of meat, this book is packed with ideas to transform even the most basic of ingredients into decadent dishes that still work with your macros. From tasty Pulled Pork Burgers to Spicy Enchiladas or Mushroom & Cheese Souffle Omelettes, these good-value, great-tasting meals will satisfy your taste buds - and your bank balance. This is keto made simple and affordable.

Psychiatry Algorithms for Primary Care is a practical, quick reference guide to psychiatric assessment and mental healthcare in general practice. Providing algorithms informed by evidence-based guidelines, this easy-to-use resource helps busy medical and healthcare professionals quickly assess mental health problems, make informed treatment decisions, and understand when referrals to specialist mental health services are appropriate. Drawing from their extensive experience in general practice and psychiatry, the authors provide clear and authoritative guidance on a wide range of common psychiatric disorders, complex scenarios, and special considerations. Unique visual management algorithms define assessment, diagnosis, investigations and management for each condition, including Bipolar Affective Disorder, Psychosis, Depression, Dementia, and Attention Deficit Hyperactivity Disorder. Up-to-date information on medication choices and counselling strategies is found throughout the text. Designed for informing swift clinical decisions in demanding primary care settings, this indispensable reference guide: Conforms to the diagnostic criteria in the current edition of the World Health Organization's International Classification of Diseases Contains algorithms informed by the Royal College of General Practitioners (RCGP), Royal College of Psychiatrists (RCPsych), and the National Institute for Health and Care Excellence (NICE) guidelines Explores common complaints that can suggest psychological or psychiatric disorders, such as insomnia and fatigue Outlines special mental health considerations related to children, intellectual disability, autism, the elderly, and pregnancy Includes appendices covering commonly prescribed drugs and physical examinations for patients with severe mental illness Features numerous self-assessment questions and links to online reference tools for General Practitioners Psychiatry Algorithms for Primary Care is a much-needed resource for medical students and trainees, physicians and healthcare professionals in general practice, nurse practitioners, and practitioners in other fields such as urgent care and emergency medicine.

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

Features * The first collective book combining accumulated knowledge and experience in the field of diabetes research using biophotonics. * Contributions from leading experts in the field. * Combines the theoretical base of the described methods and approaches, as well as providing valuable practical guidance and the latest research from experimental studies.

Encyclopedia of Respiratory Medicine, Second Edition, Six Volume Set explores the key processes of lung diseases and their diagnosis and management. The book dissects the molecular and cellular biology, physiology and immunology that underpin normal lung function, along with the aberrations that occur in respiratory diseases, from common disorders such as asthma and COPD to rarer lung diseases such as cystic fibrosis, interstitial lung diseases and pulmonary hypertension. Written in at a time when the globe is in the grip of respiratory pandemic, lung disease has never been so prominent in the public and political conscious. This new edition will provide new researchers in respiratory medicine with a solid foundation in unfamiliar topics and will update more experienced researchers seeking to step outside their core areas of research to put their work into a broader context.

This book embarks on a journey never taken before, approaching the imaging of the disease of achalasia with new pathophysiological assumptions in mind, coming from the Chicago Classification of Manometric diagnosis. Using state-of-the-art, modern x-ray technology, the authors have developed a schematic and simple approach to detection, diagnosis, and patient stadiation and prognostic stratification, for radiologists, clinicians, and students. Key Features: 1. Serves as a useful guide to structured and comprehensive reporting of barium swallows, both in achalasia and other oesophageal motility disorders. 2. Allows radiologists, both specialists, and trainees, to comprehensively understand achalasia from anatomic, pathophysiologic, therapeutic points of view, allowing for exact comprehension, detection, and reporting of the radiologic hallmarks of the disease. 3. Empowers readers to diagnose and define the exact achalasia subtype in each patient, due to the specifically developed FBF score.

Eliza Fricker gets it. Describing her perfectly imperfect experience of raising a PDA child, with societal judgements and internal pressures, it is easy to feel overwhelmed, resentful and alone. This book's comedic illustrations explain these challenging situations and feelings in a way that words simply cannot, will bring some much-needed levity back into PDA parenting. Humorous anecdotes with a compassionate tone remind parents that they are not alone, and they're doing a great job. If children are safe, happy, and you leave the house on time, who cares about some smelly socks? A light-hearted and digestible guide to being a PDA parent covering everything from tolerance levels, relationships and meltdowns to collaboration, flexibility, and self care to dip in and out as your schedule allows to help get to grips with this complex condition. This book is an essential read for any parent with a PDA child, to help better understand your child, build support systems and carve out some essential self care time guilt free.