This issue of Immunology and Allergy Clinics, guest edited by Drs. Linda S. Cox and Anna H. Nowak-Wegrzyn, is devoted to Aeroallergen and Food Immunotherapy. Articles in this issue include History of AIT and the future direction of CRD/molecular allergy; Mechanisms of aeroallergen allergen immunotherapy: SCIT and SLIT; Mechanisms underlying induction of tolerance to foods; Biomarkers for allergen immunotherapy; SCIT and SLIT; Novel delivery routes for allergy immunotherapy; Oral immunotherapy for food allergy; SLIT and EPIT for food allergy; The use of adjuvants for enhancing allergen immunotherapy efficacy; Allergen immunotherapy vaccine modification; Allergen immunotherapy outcome assessment in clinical trials and real life; Component resolved diagnosis: can it make specific AIT more specific?; Baked milk and egg diets for milk and egg allergy management; and Allergen immunotherapy practical considerations: adherence and strategies to improve.

Dr. Levy has secured the field's top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy's issue will be the most current authority on cholestatic liver disease.

This issue of Emergency Medicine Clinics, edited by Drs. Robert Vissers and Michael Gibbs, focuses on Pulmonary Emergencies. Articles include: Approach to the Adult Patient with Acute Dyspnea,Approach to the Pediatric Patient with Acute Dyspnea,Advances in Pulmonary Imaging,Respiratory Monitoring,Management of Acute Asthma and COPD,Diagnosis and Treatment of Acute Pulmonary Embolus,Pulmonary Manifestations Of Systemic Diseases,Pleural Disease,Management of Hemoptysis, and more!

This issue of PET Clinics focuses on Special Techniques and Technical Advances in PET/CT Imaging. Articles will include: PET/CT Guided FNAC/Biopsy; Dual Time Point Imaging; Overview of Conventional imaging based intervention in clinical practice; Special Techniques in PET/CT in evaluating genito-urinary malignances; Special techniques in PET/CT imaging for evaluation of head and neck cancer; PET/CT enteroclysis; Contrast media in PET/CT imaging; PET/CT guided RFA; Non-attenuated corrected PET/CT imaging and applications; and more!

This issue of Neuroimaging Clinics of North America focuses on Plaque Imaging. Articles will include: 3D carotid plaque MR imaging, Analysis of multi-contrast carotid plaque MR imaging, Incorporating carotid plaque imaging into routine clinical carotid MRA, PET-CT imaging to assess future cardiovascular risk, Utility of combining PET and MR imaging of carotid plaque, 3D carotid plaque ultrasound, Contrast-enhanced carotid plaque ultrasound, Detection of vulnerable plaque in patients with "cryptogenic stroke," Measuring plaque burden in secondary prevention of asymptomatic patients with known carotid stenosis, Plaque imaging in primary prevention of cardiovascular disease, Plaque imaging to decide on optimal treatment: medical versus CEA versus CAS, Clinical perspective of carotid plaque imaging, and more!

A great number of incarcerated youth have diagnosable psychiatric problems and, while in detention, this population experiences events that make them more vulnerable to disorders of mental health. This issue of Child & Adolescent Psychiatric Clinics is edited and authored by psychiatrists expert in working with youth in detention. Topics include Demographics of youth in detention; Mental health screening and assessment; Mental health care of detained youth and solitary confinement and restraint within juvenile detention facilities; Civil and constitutional rights of adjudicated youth; Community based alternatives to incarceration and assessment and community based planning for probation/community based alternatives; The role of the child and adolescent psychiatrist in the adjudicatory assessments; Screening and assessment of detained youth; Quality of education for youth in the juvenile detention system; Variety of out-of-home placements for juvenile offenders; Juvenile sexual offenders; Sexual exploitation of children in detention; Transfer from juvenile to adult court: Which states have the most effective models? ; Competence to stand trial; Firesetting. Clinical vignettes are presented with each topic to exemplify a case of the discussion.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery - is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.

This issue will cover everything from various therapies to alleviate symptoms or help patients learn to cope to regain normal function of their hand/or upper extremity and resume daily activities, to mechanism/anatomy and outcomes and measurement of pain.

This issue of Thoracic Surgery Clinics of North America focuses on Pulmonary Metastasectomy. Articles will include: Biology of Pulmonary Metastases; Preoperative Evaluations and Indications for Metastasectomy; Open Approaches to Pulmonary Metastases: Thoracotomy and Sternotomy; Ablative Approaches for Pulmonary Metastases: RFA, microwave, SBRT; Role of Lymphadenectomy with Pulmonary Metastasectomy; Results of Pulmonary Resection: Colorectal Carcinoma; Results of Pulmonary Resection: Sarcoma and Germ Cell Tumors; Isolated Lung Perfusion; Immunotherapy; Medical Management of Pulmonary Metastases: Is There a Role for Surgery?; Thoracoscopic Management of Pulmonary Metastases; Results of Pulmonary Resection: Other Epithelial Malignancies; Thoracoscopic Lung Suffusion; and more!

Heart failure is the only cardiovascular disease that is increasing. The impact on the critical care environment and the health care system, as a whole, is significant from both a cost and burden to the system perspective. There are 6.5 million hospital days a year and nearly $40 billion dollars in yearly health care costs attributed to heart failure in the United States. There are more Medicare monies spent for diagnosing and treating heart failure than any other Diagnosis Related Group. There is a 24% hospital re-admission rate for this diagnosis which leads to financial implications for health care systems. The human cost is also significant. Less than half of Americans diagnosed with heart failure survive greater than 5 years. The ongoing health care needs and cost of this chronic disease takes a significant toll on patients' finances, time and quality of life. Over $2.9 billion dollars is spent annually on the pharmaceutical management of heart failure in the United States. This diagnosis is the leading cause of hospitalization for patients who are 65 years of age and older. Few health care providers in the critical care environment are not affected by heart failure on a routine basis. Caring for these patients and their families is both a challenging and yet a rewarding experience. This edition will provide critical care nurses with a comprehensive heart failure review which is essential in caring for this challenging population given the dynamic health and critical care environments.

Coronary artery disease continues to be a major cause of morbidity and mortality in the United States and throughout the world. This issue of the Heart Failure Clinics provides a contemporary and concise, yet extensive, review on all aspects of the management of patients with coronary artery disease. Topics include but are not limited to: Epidemiology, Traditional and Novel Risk Factors in Coronary Artery Disease; Acute Coronary Syndromes: Unstable Angina and Non-ST Elevation Myocardial Infarction; Calcium Scoring and Cardiac Computed Tomography; Coronary Artery Disease and Diabetes Mellitus; Cardiac Syndrome X; and Revascularization Options: Coronary Artery Bypass Surgery and Percutaneous Coronary Intervention.

This issue of Physical Medicine & Rehabilitation Clinics will focus on stroke rehabilitation and will include articles such as: Mechanisms of stroke recovery, Insights from basic sciences, Stroke recovery and predictors of rehabilitation outcomes, Upper limb motor impairments, Post-stroke spasticity, Communication disorders and dysphagia, Neuropharmacology of Recovery, Robotic therapy, and many more.

Living with a skin condition can have a significant impact on way of life and emotional well-being. Psychodermatology is the practice of treating a skin condition using psychological techniques. This book is a concise guide to psychodermatology for dermatologists. Beginning with an overview providing clinicians with an understanding of the psychological issues associated with dermatological issues. The following chapters discuss different types of skin disorder and treatment strategies including meditation, psychotherapy, hypnotherapy, and psychopharmacology. The text differentiates clearly between primary and secondary psychological disorders, and psychophysiological conditions. A complete section is dedicated to assessment tools and questionnaires. Each chapter begins with a 'key points' section and includes case vignettes to assist learning. Key points Concise guide to management of psychological impact of skin disorders Covers numerous skin conditions and treatment methods Complete section provides clinicians with assessment tools and questionnaires Each chapter includes 'key points' and case vignettes

Following their issue on Sleep and Psychiatry in Adults, Drs. John Herman and Max Hirshkowitz have assembled an expert panel of authors in the topic of Sleep and Psychiatry in Children. Articles include:Kleine-Levin Syndrome;Sleep in Patient with Obsessive Compulsive Disorder;ADHD and Sleep: Diagnosis and Treatment; Relations Between Sleep, Personality, Behavioral Problems, and School Performance in Adolescents;Anxiety Disorders and Sleep in Children and Adolescents;Emotional and Cognitive Impact;REM Sleep Behavior Disorder in Children, Melatonin Treatment in Children with Developmental Disabilities and more!

The volume of elderly patients requiring anesthesia and surgery is growing rapidly. Thirty-five percent of surgeries are performed on patients older than 65 years, and in general, these patients have higher morbidity and mortality rates after anesthesia compared with their younger counterparts. One of the major challenges of treating elderly patients is the heterogeneity of the geriatric population-and the need to individualize care for each patient to provide the best outcome.

This issue provides much needed updates since Dr. Sheinfeld's issue published in 2007. Dr. Lin has assembled expert authors to provide clinicians with the full breadth of clinical updates on testicular cancer. New to this issue are articles on clinical outcomes, survivorship, and several articles on the management of Nonseminomatous Germ Cell Tumors.

Early identification and diagnosis by type and stage is the key to high survival rates with thyroid cancer. To present the pathologist with current clinical information on diagnosis, differential diagnosis, staging, and prognosis of thyroid cancers, topics presented are: Poorly differentiated thyroid carcinoma; Paraganglimoa; Immunohistochemical markers for evaluation and prognosis in thyroid carcinoma; Familial endocrine syndromes; Parathyroid enoplasia; Inflammatory lesions of the thyroid associated with cancer; Assessing biological aggression in adrenal cortical neoplasia; Pituitary neoplasia; and Pancreatic endocrine neoplasia. Peter Sadow, whose clinical practice and research involve studying the mechanisms of endocrine carcinogenesis through translational studies involving the proteomics and genomics of endocrine neoplasms, primarily of the thyroid and adrenal glands, leads this issue.

Diagnosis and Management of Dermatologic Disorders Made Easy is the second edition of this comprehensive and highly illustrated guide to skin disorders. The book is divided into 23 chapters, beginning with a 'Global Panorama of Dermatology' and chapters on the structure and physiology of the skin. Subsequent chapters cover the diagnosis of specific skin disorders, covering a broad range of dermatologic diseases from scabies to leprosy. The book concludes with chapters on sexually transmitted diseases, HIV and AIDS. This new edition has been thoroughly revised and expanded, with new clinical material on eczema and dermatitis, and over 400 full colour images, illustrations and tables. Brand new full colour photographs and charts enhance many topics, including new photographs of opportunistic infections in chapters on STDs, HIV and AIDs. Diagnosis and Management of Dermatologic Disorders Made Easy is a straightforward guide to range of skin conditions. This new edition is ideal for dermatologists wishing to stay up to date on current diagnostic procedures. Key Points Latest edition of comprehensive guide to the diagnosis and management of skin conditions Over 400 full colour images, illustrations and tables New photographs of opportunistic infections in STDs, HIV and AIDS Previous edition (9788184489484) published 2010

This issue of Clinics in Geriatric Medicine is devoted to Nutrition in Older Adults. Guest Editor John E. Morley, MD has assembled a group of expert authors to review the following topics: Anorexia of Aging; Protein and Older Persons; Screening for Malnutrition in Older People; Obesity and Aging; Vitamins; Sarcopenia; Diabetes: Nutrition and Exercise; Frailty, Exercise and Nutrition; Dehydration; Cholesterol and Older Persons; Cognition and Nutrition; and Gastric Emptying in the Elderly.

Upper gastrointestinal bleeding is the leading emergency leading to hospitalization and urgent endoscopy. The field of gastrointestinal bleeding is rapidly evolving. The epidemiology is changing with more complex older patients on anticoagulant and antithrombotic agents presenting with upper gastrointestinal bleeding. The initial management has rapidly evolved with new transfusion thresholds, the use of risk stratification scores and no more nasogastric tubes. There is new data and recommendations on optimal timing of endoscopy. Medical therapies have also evolved with changes in proton pump inhibitor administration and the use of prokinetics to improve endoscopic visualization. Many modifications in endoscopic therapy have recently been advanced including the use of endoscopic ultrasound guided angiotherapy, topical sprays (i.e. Hemospray) and over-the-scope clips. In order to give optimal care to patients, it is critical that practicing gastroenterologists are aware of the many recent advances in management of patients with upper gastrointestinal bleeding.

This issue of Heart Failure Clinics examines the critical role of team-based care in the management of patients with heart failure. Articles address Team-Based Care for Prevention, Patients Hospitalized with Heart Failure, Transitions of Care, Outpatients, Managing Cardiac Comorbidities, Managing Non-cardiac Conditions, Cardiac Rehabilitation and Exercise Training, External Telemonitoring, Ambulatory Hemodynamic Cardiac Device Monitoring, Advanced Heart Failure, and Palliative and End-of-Life Care.

This issue provideds a comprehensive update to Sleep Medicine in the Intensive Care Unit, with editors Vipin Malik and Teofilo Lee-Chiong assembling a line-up of key topics such as:Sleep Neurobiology and Critical Care Illness,Obesity Hypoventilation Syndrome and Respiratory Failure,Obstructive Sleep Apnea,Non-Invasive Ventilation in Critically Ill Patients,Restless Leg Syndrome,Sleep and Endocrine System,Congestive Heart Failure and Central Sleep Apnea,Circadian Dysrhythmias,Neuromuscular Disorders and Sleep in Critically Ill Patients, Perioperative Issues and Sleep Disordered Breathing, Seizures, and more!

This issue of Cardiology Clinics examines the timely topic of Lipidology. In addition to the New Recommendations - ACC/AHA Lipid Guidelines, the issue also includes Familial Hypercholesterolemia; LDL Apheresis; Lipids in Pregnancy and Women; Diabetes and Lipidology; Diabetic Dyslipidemia; Fatty Liver Disease; Lipids and HIV Disease; Residual Risk; and Statins' effects on diabetes, cognition, and liver safety.

This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Joaquin Bellmunt, is devoted to Bladder Cancer. Articles in this issue include: Diagnosis and Staging of Bladder Cancer; Epidemiology of Bladder Cancer; Molecular Biology of Bladder Cancer; Pharmacogenomics in Bladder Cancer; Management of Non-muscle Invasive Bladder Cancer; Non-urothelial Bladder Cancer and Rare Variant Histologies; Management of UUT; New Trends in Surgical Management of Bladder Cancer; Bladder Preservation Strategies; Perioperative Therapy of Bladder Cancer (Neoadjuvant and Adjuvant); First Line Treatment and Prognostic Factors of Metastatic Disease: Platinum Eligible Patients; First Line Treatment of Metastatic Disease: Platinum Ineligible Patients; Salvage Therapy in Metastatic Disease; and Future Directions and Targeted Therapies in Bladder Cancer.

Community-based primary care physicians are routinely challenged as they stabilize, evaluate, and care for term and late-preterm neonates. Although there have been many spectacular advances in care of neonates, the challenges and successes of caring for the most preterm, very low birth-weight newborns seem to dominate presentations and the Pediatric literature. This issue concentrates on the current evidence and the collected experience of neonatologists regarding the basics of caring for the vast majority of newborns. The newest recommendations of multiple organizations (including the AAP) are presented, including the rationale for each recommendation as well as controversial issues. The individual articles will provide the primary care provider with a comprehensive foundation for care of the neonate.