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Islet Transplantation and Beta Cell Replacement Therapy (Hardcover)
Loot Price: R6,472
Discovery Miles 64 720
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Islet Transplantation and Beta Cell Replacement Therapy (Hardcover)
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Beta cell replacement through transplantation remains the only
treatment option for Type 1 diabetes enabling restoration of
near-physiological glucose levels without significant hypoglycemia.
Outlining the most recent advances and research breakthroughs, this
practical guide and reference work explores the impact of islet
cell transplantation and brings together leading multidisciplinary
proponents critical to future success in the field. Edited by a
surgeon and an endocrinologist at the forefront of the technology,
this volume considers challenges associated with this procedure
including lack of sufficient donor organs and the side effects of
immunosuppressive therapy, as well as the potential benefits for
current and future patients. Islet Transplantation and Beta Cell
Replacement Therapy, after a brief historical overview, examines:
the key role of endocrinologists in holistic assessment and
selection of islet transplant recipients the factors underlying
attrition of islet function over time and need for enhanced graft
monitoring post transplantation future in vivo islet imaging
setting up new clinical islet transplant programs by outlining
potential models and pitfalls-including cost effectiveness and
sustainable integrated approaches clinical outcomes and the future
direction for islet transplantation, including alternative sources
of beta cells, to meet future clinical needs through
xenotransplantation, new insulin-producing cells from adult tissue,
and stem cell banks
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