0
Your cart

Your cart is empty

Books > Medicine > Other branches of medicine > Pharmacology > Medical toxicology

Buy Now

New Horizons in Predictive Drug Metabolism and Pharmacokinetics (Hardcover) Loot Price: R5,930
Discovery Miles 59 300
New Horizons in Predictive Drug Metabolism and Pharmacokinetics (Hardcover): Alan G. E. Wilson

New Horizons in Predictive Drug Metabolism and Pharmacokinetics (Hardcover)

Alan G. E. Wilson

Series: Drug Discovery

 (sign in to rate)
Loot Price R5,930 Discovery Miles 59 300 | Repayment Terms: R556 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and pharmacokinetics. Readers will find a thorough exploration of their predictive role in impacting drug discovery and development and in improving the success rate and safety assessment of pharmaceuticals and industrial or occupational chemicals. Chapters not only focus on the current state of art, with distinct examples, but on future needs and approaches likely to improve our prediction of potential human risk. Discussions of critical properties that are determinants of a compound's metabolic and pharmacokinetic fate follow introductory chapters. The Drug Discovery process increasingly incorporates pharmacokinetics and drug metabolism screening and focus has shifted towards in silico, computational and systems biology approaches. Core chapters reflect this and the recent interest and need to assess the role of transporters, along with drug metabolizing enzymes, as potential determinants of pharmacokinetic behaviour, toxicity and drug-drug interactions. Lastly, chapters cover the issues and factors involved in translating pharmacokinetics from in silico to in vivo and from animal models to man, and postulate future directions and opportunities. Leading experts from academia, industry and regulatory bodies across the globe contribute their knowledge to this book, which scientists involved in many aspects of the drug discovery process, as well as regulators and postgraduate students, will find a useful resource.

General

Imprint: Royal Society of Chemistry
Country of origin: United Kingdom
Series: Drug Discovery
Release date: November 2015
First published: 2016
Editors: Alan G. E. Wilson
Dimensions: 234 x 156 x 29mm (L x W x T)
Format: Hardcover - Unsewn / adhesive bound
Pages: 422
ISBN-13: 978-1-84973-828-6
Categories: Books > Medicine > Other branches of medicine > Pharmacology > Medical toxicology
Promotions
LSN: 1-84973-828-9
Barcode: 9781849738286

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Handbook of Arsenic Toxicology
Swaran Jeet Singh Flora Hardcover R4,620 Discovery Miles 46 200
Comprehensive Pharmacology
Terry Kenakin Hardcover R106,108 Discovery Miles 1 061 080
History of Modern Clinical Toxicology
Alan Woolf Paperback R2,723 Discovery Miles 27 230
Drug Hepatotoxicity, An Issue of Clinics…
Vinod Rustgi Hardcover R2,264 Discovery Miles 22 640
Targeting Chronic Inflammatory Lung…
Kamal Dua, Philip M. Hansbro, … Paperback R4,285 Discovery Miles 42 850
Advances in Molecular Toxicology, Volume…
James C. Fishbein, Jacqueline M. Heilman Hardcover R7,027 Discovery Miles 70 270
Emerging Nanotechnologies in Immunology…
Ranjita Shegokar, Eliana B. Souto Hardcover R3,510 R3,280 Discovery Miles 32 800
Handbook of Arsenic Toxicology
Swaran Jeet Singh Flora Hardcover R4,258 R3,825 Discovery Miles 38 250
Fundamentals of Toxicologic Pathology
Matthew A. Wallig, Wanda M. M Haschek, … Hardcover R4,611 Discovery Miles 46 110
Emergency management of acute poisoning
Dr. A. Howard Paperback R1,050 R985 Discovery Miles 9 850
Hygienic Design of Food Factories
John Holah, Huub Lelieveld, … Paperback R7,505 Discovery Miles 75 050
Present Knowledge in Food Safety - A…
Michael E. Knowles, Lucia Anelich, … Paperback R4,433 Discovery Miles 44 330

See more

Partners