This volume presents a review of modern force spectroscopy,
including fundamentals of intermolecular forces, technical aspects
of the force measurements, and practical applications. The Handbook
begins with a review of fundamental physics of loading single and
multiple chemical bonds on the nanometer scale with a discussion of
thermodynamic and kinetic models of binding forces and dissipation
effects in nanoscale molecular contacts, covers practical aspects
of modern single-molecule level techniques, and concludes with
applications of force spectroscopy to chemical and biological
processes. Computer modeling of force spectroscopy experiments is
addressed as well. In sum, Handbook of Molecular Force Spectroscopy
is a comprehensive, authoritative guide to planning, understanding,
and analyzing modern molecular force spectroscopy experiments with
an emphasis on biophysical research.
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