In vitro fertilization has resulted in an estimated 4000-5000
births in the world. The procedure has been accepted in Europe,
America and Australia and several hundred IVF clinics are operating
successfully. The newer procedures of GIFf, embryo freezing and
donor oocyte IVF have become established and are dealt with in
several chapters. GIFf has become the procedure of choice for
patients with infertility of unknown origin. Oocyte freezing
represents an important new technology which is being developed.
The routine IVF procedure has improved slightly; variation in
results can be reduced by quality control of laboratory and
clinical techniques. Male factor infertility has been dealt with by
IVF in mild and moderate cases, but newer techniques will be
required to deal with severe problems in the male. Most countries
have accepted that the straightforward IVF pro cedure is ethical.
Limitations concerning the use of donor oocytes and embryo
experimentation exist in some religions and countries; legal
control of the new reproductive technologies ranges from the
passage of statutes to no control at all. Many countries are still
considering the need for legislative control. The text endeavours
to indicate new areas of importance and to guide those organizing
services as to how to introduce newer technolo gies.
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