In the clinic at Giessen during the last few years there has been
an extensive programme of research into the various aspects of
lesions of the diencephalon and brain stem and the associated
autonomic and metabolic disturbances. As a continuation of this
research programme Ernst Grote has investigated the central
neuronal and hormonal factors acting on the peripheral regulation
of glucose metabolism and their diverse inter-relationships. This
research was made possible not only by the availability of
well-documented clinical and experi mental material with primary
and secondary lesions of the hypo thalamus and brain stem, but also
by the advances in clinical endo crinology and the development of
radio-immuno-assays. By continuous systematic investigation of the
basic values and their reaction to stress-tests, as well as to
trauma and operation, he has elucidated the basic facts of the
central and peripheral mechanisms which are concerned in the
regulation of glucose, and also their disturbances. Of particular
significance are his descriptions and interpretations of the
characteristic hypothalamic syndromes, as combinations of
hyperglycaemia, hyperinsulinaemia and hyperglucagonaemia; dif
ferent syndromes are produced by lesions at various levels of the
brain stem and in central brain death. From this starting point it
was possible to develop a rational treatment of this hormonal dys
regulation by means of somatostatin."
General
| Imprint: |
Springer-Verlag
|
| Country of origin: |
Austria |
| Series: |
Acta Neurochirurgica Supplement, 31 |
| Release date: |
June 1981 |
| First published: |
1981 |
| Authors: |
E. H. Grote
|
| Dimensions: |
229 x 152 x 9mm (L x W x T) |
| Format: |
Paperback
|
| Pages: |
160 |
| Edition: |
Softcover reprint of the original 1st ed. 1981 |
| ISBN-13: |
978-3-211-81619-6 |
| Categories: |
Books >
Medicine >
Surgery >
Neurosurgery
|
| LSN: |
3-211-81619-4 |
| Barcode: |
9783211816196 |
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