Progress in Medicinal Chemistry, Volume 42 (Hardcover)

This volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.

General

Imprint:	Elsevier Science Ltd
Country of origin:	United Kingdom
Series:	Progress in Medicinal Chemistry
Release date:	April 2004
First published:	2004
Authors:	F.D. King
Dimensions:	229 x 152 x 23mm (L x W x T)
Format:	Hardcover
Pages:	450
ISBN-13:	978-0-444-51143-0
Categories:	Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Promotions
LSN:	0-444-51143-1
Barcode:	9780444511430

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