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Pain / Brain Stimulation in the Treatment of Pain (Hardcover, New)
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Pain / Brain Stimulation in the Treatment of Pain (Hardcover, New)
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In the past years, neuroimaging techniques provided a better
insight into mechanisms involved in the development and maintenance
of chronic pain. Chronic pain does not develop as a simple direct
result of activity in nociceptive fibres following a traumatic
event, but rather represents a consequence of dynamic plastic
changes in sensory, affective and cognitive systems and related
neuronal networks. The functional neural changes associated with
pain include both adaptive compensatory changes, as well as
maladaptive changes that may contribute to dysfunction of involved
anatomical and physiological systems. In accordance, research
findings indicated that patients with some chronic pain syndromes
developed functional reorganisation of certain brain structures
(for example in somatosensory -- or motor cortices). Since research
studies have shown that reversal of pathological cortical changes
in chronic-pain patients is accompanied by pain relief, a
modulation of brain excitability seems to be a promising approach
to address pain related to central hyperexcitability. This book
discusses this topic and how brain stimulation techniques aim to
selectively enhance adaptive patterns of neural activity, suppress
the maladaptive ones, and restore the balance in disturbed neuronal
networks.
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