In this yearbook for 2011 we start out with a description of
research from the University of Toronto in Canada on bone
metastases. The next section also from the Odette Cancer Centre,
Sunnybrook Health Sciences Centre is about brain metastases, a
frequent manifestation of advanced cancer devastating to the
patient as typically patients do not survive more than a year upon
diagnosis and the treatment itself often results in significant
side effects that impact a patients quality of life. The next
section is on neuroplasticity, which reflects the ability of human
brain to alter the pattern of neural activation in response to
previous experience, and recent findings indicate that the effects
of experience can lead to both structural as well as functional
reorganisation. If neuromodulatory approaches prove to be safe and
effective, they could change the current view of best practice in
pain management and assume a significant role in the clinic. This
yearbook will present you with the latest research on pain
management.
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