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Books > Medicine > Clinical & internal medicine > Musculoskeletal medicine
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Fibrosis Research - Methods and Protocols (Hardcover, 2005 ed.)
Loot Price: R4,656
Discovery Miles 46 560
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Fibrosis Research - Methods and Protocols (Hardcover, 2005 ed.)
Series: Methods in Molecular Medicine, 117
Expected to ship within 10 - 15 working days
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Leading investigators review the highlights of current fibrosis
research and the experimental methodologies used uncover the
mechanisms that drive it. In their discussion of research
methodologies utilizing cultured cells to model various aspects of
the fibrotic response in vitro, the authors describe the isolation,
characterization, and propagation of mesenchymal cells, and
highlight the similarities and differences between methods that are
appropriate for different types of fibroblasts. Approaches for
studying collagen gene regulation and TGF-b production are also
discussed, along with experimental methodologies utilizing animal
models to study the pathogenesis of fibrosis. The protocols follow
the successful Methods in Molecular Medicine(TM) series format,
each offering step-by-step laboratory instructions, an introduction
outlining the principles behind the technique, lists of the
necessary equipment and reagents, and tips on troubleshooting and
avoiding known pitfalls.
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