The authors address in particular the role of hormones and their
links with other maternal environmental mediators in developmental
programming. The crucial nature of the placenta as an interface and
target between maternal and foetal environments is addressed.
Emphasis is made on the emerging science of epigenetics as a
potential explanation for how environmental events that occur
during brief windows of development may exert effects that impact
upon somatic cells through many rounds of mitosis for much of the
life span of the subsequent organism.
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