This detailed book provides methodological information on cardiac
gene delivery, from classic to state-of-the-art technologies and
techniques. Efficient, cardiac-specific, and safe vectors, as well
as refined vector delivery methods, are key for successful cardiac
gene transfer and eventually for improving patients' outcomes.
Newer vectors and more efficient vector delivery methods have the
potential to dramatically improve gene transduction efficacy, while
novel gene manipulation techniques enforce the therapeutic power
and broaden disease targets. Written for the highly successful
Methods in Molecular Biology series, chapters include introductions
to their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Cardiac Gene Therapy: Methods and
Protocols serves as a valuable tool for molecular biologists and
physiologists in the cardiology field conducting cardiac gene
transfer research, which will ultimately lead to further
advancements in the vital field.
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