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Books > Medicine > General issues > Medical equipment & techniques

Preventable - How A Pandemic Changed The World & How To Stop The Next One (Paperback): Devi Sridhar Preventable - How A Pandemic Changed The World & How To Stop The Next One (Paperback)
Devi Sridhar
R320 R256 Discovery Miles 2 560 Save R64 (20%) In Stock

The definitive story of COVID-19 and how global politics shape our health - from a world-leading expert and the pandemic's go-to science communicator

Professor Devi Sridhar has risen to prominence for her vital roles in communicating science to the public and speaking truth to power. In Preventable she highlights lessons learned from outbreaks past and present in a narrative that traces the COVID-19 pandemic - including her personal experience as a scientist - and sets out a vision for how we can better protect ourselves from the inevitable health crises to come.

In gripping and heartfelt prose, Sridhar exposes the varied realities of those affected and puts you in the room with key decision makers at crucial moments. She vibrantly conveys the twists and turns of a plot that saw: deadlier varients emerge (contrary to the predictions of social media pundits who argued it would mutate to a milder form); countries with weak health systems like Senegal and Vietnam fare better than countries like the US and UK (which were consistently ranked as the most prepared); and the quickest development of game-changing vaccines in history (and their unfair distribution)

Combining science, politics, ethics and economics, this definitive book dissects the global structures that determine our fate, and reveals the deep-seated economic and social inequalities at their heart - it will challenge, outrage and inspire.

Dopamine Nation - Finding Balance in the Age of Indulgence (Paperback): Anna Lembke Dopamine Nation - Finding Balance in the Age of Indulgence (Paperback)
Anna Lembke
R305 R244 Discovery Miles 2 440 Save R61 (20%) Ships in 5 - 10 working days

'Her stories have the power to transform your life' Lori Gottlieb, bestselling author of Maybe You Should Talk to Someone 'Radically changes the way we think about mental illness, pleasure, pain, reward and stress' Daniel Levitin, bestselling author of The Organized Mind 'Brilliant . . . riveting, scary, cogent and cleverly argued' Beth Macy, author of Dopesick We are a wired generation. In these fast-paced times we are constantly bombarded by high-reward, high-dopamine stimuli. From texting to social media, food to drugs, gambling to shopping, we have become addicted to fleeting and distracting pleasures that are making us sick. In Dopamine Nation, psychiatrist and bestselling author Dr Anna Lembke reveals why our relentless pursuit of pleasure leads to pain and what we can do about it. Bringing together cutting-edge neuroscience with the gripping real life experiences from her clinical practice, Lembke explores how contentment and connectedness are essential tools in keeping dopamine in check. This is an essential book for anyone wanting to find a balance for a happier life.

Advanced Introduction to Artificial Intelligence in Healthcare (Paperback): Tom Davenport, John Glaser, Elizabeth Gardner Advanced Introduction to Artificial Intelligence in Healthcare (Paperback)
Tom Davenport, John Glaser, Elizabeth Gardner
R599 Discovery Miles 5 990 Ships in 12 - 17 working days

Elgar Advanced Introductions are stimulating and thoughtful introductions to major fields in the social sciences, business and law, expertly written by the world's leading scholars. Designed to be accessible yet rigorous, they offer concise and lucid surveys of the substantive and policy issues associated with discrete subject areas. Providing a comprehensive overview of the current and future uses of Artificial Intelligence (AI) in healthcare, this Advanced Introduction discusses the issues surrounding the implementation, governance, impacts and risks of utilising AI in health organizations Key Features: Advises healthcare executives on how to effectively leverage AI to advance their strategies and plans and support digital transformation Discusses AI governance, change management, workforce management and the organization of AI experimentation and implementation Analyzes AI technologies in healthcare and their impacts on patient care, medical devices, pharmaceuticals, population health, and healthcare operations Provides risk mitigation approaches to address potential AI algorithm problems, liability and regulation Essential reading for policymakers, clinical executives and consultants in healthcare, this Advanced Introduction explores how to successfully integrate AI into healthcare organizations and will also prove invaluable to students and scholars interested in technological innovations in healthcare.

Flesh Made New: the Unnatural History and Broken Promise of Stem Cells (Paperback): John Rasko, Carl Power Flesh Made New: the Unnatural History and Broken Promise of Stem Cells (Paperback)
John Rasko, Carl Power
R395 Discovery Miles 3 950 Ships in 12 - 17 working days

The dazzling promise of stem cell medicine: does it work and will it save us? Two experts look at the hype For decades, we've been anticipating the dawn of regenerative medicine. Again and again, we've been promised that stem cells will soon cure just about every ill imaginable. If not tomorrow, then the next day, or the day after that, and so on. We're still waiting. This book is an antidote to hype and a salve to soothe the itch for stem-cell salvation. In it, Professor John Rasko, a leading physician-scientist, and writer-historian Carl Power take us on a wild historical tour of this scandal-prone field. They expose all the dirty little secrets that the hype merchants prefer to ignore - the blunders and setbacks, confusions and delusions, tricks and lies. You'll meet Alexis Carrel, who discovered how to cultivate cells in a test tube: celebrity surgeon, scientific genius and suspected Nazi sympathiser, he opened the field of modern cell science with an experiment so bogus it blocked the way forward for the next 50 years. You'll meet Don Thomas, who developed bone marrow transplantation - the first successful stem-cell therapy - but only after a miserable decade in which most of his patients died. Alongside true stem-cell pioneers, you'll meet charlatans who cooked their data and claimed fake cures - sometimes with fatal consequences. Is there any good news? Which of the many promises of stem-cell research have been kept? And what of the future? Rasko and Power insist that we can only know where we're going if we have a sense of where we've been. Their study tears down the hype surrounding stem cells in order to reveal what's still worth hoping for. PRAISE 'If you love some scandal with your science - or some science with your scandal - this is THE book for you. Brilliant stuff' Adam Spencer, University of Sydney 'Science, skulduggery and snake oil salesmen ... it is a revolution in medicine but who knew the story of stem cell science was such a ripping yarn!' Fran Kelly, ABC Radio National Breakfast 'Science isn't magic: it's a human enterprise. This enthralling book tells of high achievement and astonishing blunders in a vital field of research' Robyn Williams, science journalist and broadcaster 'A masterpiece in myth-busting which helps separate fact from fiction in the world of regenerative medicine. It shines a light on some episodes in medical history many would rather forget but also shows a way forward for stem cell research breakthroughs grounded in solid science' Sophie Scott, national medical reporter, ABC 'The stem cell revolution: myths, mistakes but mighty medical masterpiece' Sir Gustav Nossal, AC CBE FRS FAA, Australian of the Year 2000 'A compelling (and compulsory) read for anyone entranced by the latest media-promoted breakthroughs in medical research, or planning translation of new biomedical research into clinical practice' Ian Frazer, AC, FRCPE, FRCPA, FAA, FTSE Australian of the Year 2006, Australian Living Treasure 2012 'Is it really stem cells' turn to revolutionise health care? When you come across a train wreck, keep reading! You'll discover that stem cells reveal medicine in its most provocative and challenging light' Antony Basten AO FAA FTSE 'Flesh Made New is a revelation for the general reader about what lies beneath the surface of exciting scientific advances ... The book shows the value of patience and trust in robust evidence-based scientific research, and where things go off the rail, for whistleblowers and experts like the authors of this book' Lucy Turnbull AO, businesswoman, urbanist and philanthropist

Conquering Consumption with Exercise and Nature (Paperback): David Thomas Conquering Consumption with Exercise and Nature (Paperback)
David Thomas
R495 Discovery Miles 4 950 Ships in 12 - 17 working days

Consumption was the deadliest, most common disease that mankind has faced up till now. Three billion people in Europe and North America died between the fourteenth and the end of the eighteenth century. It was a death sentence with no known cause which led to the development of unusual empirical therapies. Lucky Consumptive patients reached a Sanatorium. Sanatoria were developed to house sick patients in an environment where they stood the best chance of recovery from their illness. There was no organised healthcare system and funding for a Sanatorium depended upon provision provided by wealthy individuals, or societies. Charles Dunnell Rudd was a Cape Merchant who had made a fortune in South Africa successfully prospecting for Gold and Diamonds. His mother had died from Consumption and he wished to invest some of his money in building a Sanatorium. It had been shown that Consumptive patients survived longer if they took vigorous exercise, slept out of doors, and were nursed on higher land near to forests. Rudd anonymously purchased raised land at Northwood for this purpose. Helena (later Princess Christian) was Queen Victoria's third daughter, and had a marked social awareness, arranging charitable meals for the less fortunate. She was very hard working and became the Principal Patron for Mount Vernon Hospital, donating money and attending annual fundraising Festival Dinners. Contemporary photographs from this period show female patients walking around the grounds and occupying designated rest shelters. The male patients had a more vigorous lifestyle, working in the gardens and sleeping in their beds out of doors. Those surviving often acquired new skills which might enhance their future employment prospects. These measures greatly improved the prognosis for consumptive patients. After Koch discovered the Tubercle Bacillus effective curative anti-tuberculous therapy evolved.

Biomedical Informatics - Computer Applications in Health Care and Biomedicine (Hardcover, 5th ed. 2021): Edward H. Shortliffe,... Biomedical Informatics - Computer Applications in Health Care and Biomedicine (Hardcover, 5th ed. 2021)
Edward H. Shortliffe, James J. Cimino; Volume editing by Michael F. Chiang
R3,076 R2,849 Discovery Miles 28 490 Save R227 (7%) Ships in 9 - 15 working days

This 5th edition of this essential textbook continues to meet the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in biomedical informatics and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides the tools for study required for readers to comprehend, assess, and utilize biomedical informatics and health IT. It focuses on practical examples, a guide to additional literature, chapter summaries and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use. Biomedical Informatics: Computer Applications in Health Care and Biomedicine reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in care coordination and the melding of genomics with innovations in clinical practice and treatment. New and heavily revised chapters have been introduced on human-computer interaction, mHealth, personal health informatics and precision medicine, while the structure of the other chapters has undergone extensive revisions to reflect the developments in the area. The organization and philosophy remain unchanged, focusing on the science of information and knowledge management, and the role of computers and communications in modern biomedical research, health and health care.

Preventable - How A Pandemic Changed The World & How To Stop The Next One (Paperback): Devi Sridhar Preventable - How A Pandemic Changed The World & How To Stop The Next One (Paperback)
Devi Sridhar
R350 R280 Discovery Miles 2 800 Save R70 (20%) In Stock

Preventable uses the spellbinding story of the COVID-19 pandemic to show how global politics shape our health.

Professor Devi Sridhar has risen to prominence for her vital roles in communicating science to the public and speaking truth to power. In Preventable she highlights lessons learned from outbreaks past and present in a narrative that traces the COVID-19 pandemic - including her personal experience as a scientist - and sets out a vision for how we can better protect ourselves from the inevitable health crises to come.

In gripping and heartfelt prose, Sridhar exposes the varied realities of those affected (from the jailed doctor in Wuhan who sounded the alarm, and the bored passengers marooned on the Diamond Princess cruise ship, to the daily nightmares of exhausted healthcare workers), and puts you in the room with key decision makers at crucial moments (from over-confident heads of states and their hesitant scientific advisors, to the beleaguered leaders of global health organisations).

Sridhar vibrantly conveys the twists and turns of a plot that saw: deadlier variants emerge (contrary to the predictions of social media pundits who argued it would mutate to a milder form); the Pyrrhic victory in many countries of the false narrative of health versus the economy (those countries which controlled the virus, like Taiwan and Denmark, had a steadier recovery); countries with weak health systems like Senegal and Vietnam fare better than countries like the US and UK (which were consistently ranked as the most prepared); and the quickest development of game-changing vaccines in history (and their unfair distribution).

Combining science, politics, ethics and economics, this definitive book dissects the global structures that determine our fate, and reveals the deep-seated economic and social inequalities at their heart - it will challenge, outrage and inspire.

Biomolecules and Pharmacology of Medicinal Plants, 2-volume set (Hardcover): T. Pullaiah Biomolecules and Pharmacology of Medicinal Plants, 2-volume set (Hardcover)
T. Pullaiah
R8,066 Discovery Miles 80 660 Ships in 12 - 17 working days

This two-volume book, Biomolecules and Pharmacology of Medicinal Plants, will be a valuable desk reference book on bioactives and pharmacology of medicinal plants. Listing the medicinal plants by species, each of these 77 chapters detail the plants' bioactive phytocompounds and their chemical structures along with their pharmacological activities and properties. These include the plants' antiviral, antibacterial, antifungal, antioxidant, anticancer, anti-inflammatory, anti-diabetic, hepatoprotective, cardioprotective, and nephroprotective properties. Bioactive compounds typically occur in small amounts, and they have more subtle effects than nutrients. Bioactive compounds influence cellular activities that modify the risk of disease and cure and alleviate disease symptoms. These compounds can act as antioxidants, enzyme inhibitors and inducers, inhibitors of receptor activities, and inducers and inhibitors of gene expression among other actions. A wide array of biological activities and potential health benefits of medicinal plants have been reported, which include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, antidiabetic properties as well as protective effects on the liver, kidney, heart, and nervous system. The volumes will be a must-have reference for pharmacy institutes and pharmacy professors, phytochemists and research scholars, botanists working with medicinal plants, and postgraduate students of pharmacy and medicine round the world. The comprehensive information presented here provides an invaluable source to aid in the development of new drugs.

Human histology (Book): H.L. Coetzee, G.P. Loots Human histology (Book)
H.L. Coetzee, G.P. Loots
R895 R812 Discovery Miles 8 120 Save R83 (9%) Ships in 7 - 10 working days

In this publication, description of the basic histology tissues is followed by a description of the histology of the different organs and systems in the human. The subject contents is presented on a relevant clinical level, and students in both medicine and dentistry, as well as related health professions, such as nursing, occupational therapy and physiotherapy, will find it simple and meaningful. The terminology used in the publication correlates with the writing style used as standard in English medical, dental and health care science' schools.

Stem Cell Therapy - A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives (Paperback): Neil H Riordan Stem Cell Therapy - A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives (Paperback)
Neil H Riordan
R913 Discovery Miles 9 130 Ships in 10 - 15 working days
How to Read a Paper - The Basics of Evidence-based  Medicine and Healthcare, 6th Edition (Paperback, 6th Edition): Tm Greenhalgh How to Read a Paper - The Basics of Evidence-based Medicine and Healthcare, 6th Edition (Paperback, 6th Edition)
Tm Greenhalgh
R946 R863 Discovery Miles 8 630 Save R83 (9%) Ships in 7 - 13 working days

Required reading in many medical and healthcare institutions, How to Read a Paper is a clear and wide-ranging introduction to evidence-based medicine and healthcare, helping readers to understand its central principles, critically evaluate published data, and implement the results in practical settings. Author Trisha Greenhalgh guides readers through each fundamental step of inquiry, from searching the literature to assessing methodological quality and appraising statistics. How to Read a Paper addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. Now in its sixth edition, this informative text includes new and expanded discussions of study bias, political interference in published reports, medical statistics, big data and more. Offers user-friendly guidance on evidence-based healthcare that is applicable to both experienced and novice readers Authored by an internationally recognised practitioner and researcher in evidence-based healthcare and primary care Includes updated references, additional figures, improved checklists and more How to Read a Paper is an ideal resource for healthcare students, practitioners and anyone seeking an accessible introduction to evidence-based healthcare.

Advanced Introduction to Artificial Intelligence in Healthcare (Hardcover): Tom Davenport, John Glaser, Elizabeth Gardner Advanced Introduction to Artificial Intelligence in Healthcare (Hardcover)
Tom Davenport, John Glaser, Elizabeth Gardner
R2,722 Discovery Miles 27 220 Ships in 12 - 17 working days

Elgar Advanced Introductions are stimulating and thoughtful introductions to major fields in the social sciences, business and law, expertly written by the world's leading scholars. Designed to be accessible yet rigorous, they offer concise and lucid surveys of the substantive and policy issues associated with discrete subject areas. Providing a comprehensive overview of the current and future uses of Artificial Intelligence (AI) in healthcare, this Advanced Introduction discusses the issues surrounding the implementation, governance, impacts and risks of utilising AI in health organizations Key Features: Advises healthcare executives on how to effectively leverage AI to advance their strategies and plans and support digital transformation Discusses AI governance, change management, workforce management and the organization of AI experimentation and implementation Analyzes AI technologies in healthcare and their impacts on patient care, medical devices, pharmaceuticals, population health, and healthcare operations Provides risk mitigation approaches to address potential AI algorithm problems, liability and regulation Essential reading for policymakers, clinical executives and consultants in healthcare, this Advanced Introduction explores how to successfully integrate AI into healthcare organizations and will also prove invaluable to students and scholars interested in technological innovations in healthcare.

The Biofuels Deception - Going Hungry on the Green Carbon Diet (Paperback): Okbazghi Yohannes The Biofuels Deception - Going Hungry on the Green Carbon Diet (Paperback)
Okbazghi Yohannes
R625 Discovery Miles 6 250 Ships in 12 - 17 working days

There is by now no question among informed people that the Earth is undergoing severe climate change - soon to become catastrophic, if humans don't take drastic measures to stop it. Heroically into the fray steps the biofuel industry, announcing to millions of anxious consumers that this eco-crisis can be averted if only they turn away from fossil fuels, to the saving power of synthetic bioproducts. But, although eliminating fossil fuels is essential, the manufacture of biofuels has far more to do with sating profit-hungry corporations than with saving the Earth. Combining meticulous scientific narrative with devastating economic analysis, The Biofuels Deception argues that the seemingly innovative, hopeful campaign for "green energy" is actually driven by bio-technology industries and global grain-trading corporations. These corporate players are motivated by a late-capitalist need to cope with a crisis of accumulation; they have no real interest in mitigating climate-change, alleviating poverty, or even creating "clean" energy. In fact, the manufacture of biochemical, bioplastics, and biomaterials, writes Okbazghi Yohannes, portends horrific contradictions and disastrous consequences for nature and society. Actually confronting climate change and the rampant inequality it engenders, Yohannes says, requires two steps. The first is to understand the driving socioeconomic forces behind the biofuels industry. The second is to unravel the tapestry of deceit itself. This book is a necessity for any scholar or environmental activist interested in seeing beyond corporate chimeras to actual environmental solutions.

A Guide to Laboratory Investigations (Paperback, 7th edition): Michael F. McGhee, Caroline A. Saxelby, Niall Mckay A Guide to Laboratory Investigations (Paperback, 7th edition)
Michael F. McGhee, Caroline A. Saxelby, Niall Mckay
R1,021 Discovery Miles 10 210 Ships in 12 - 17 working days

The seventh edition of this concise, highly practical guide to the interpretation of normal and abnormal laboratory results is fully revised and expanded, with updates on established and familiar tests, as well as interpretations on recent developments. With increasing responsibility being placed on primary care, the book includes guidelines on specific clinical conditions such as heart failure, management of female infertility, specific lipid monitoring in diabetes and guidance for monitoring renal failure. It also includes suggestions for appropriate laboratory tests in certain clinical situations, for example: dementia screen, screening tests when a patient presents with a neuropathy, and appropriate tests for patients presenting with hypertension, chronic fatigue syndrome, erectile dysfunction and gynaecomastia. Completely up-to-date, A Guide to Laboratory Investigations, Seventh Edition remains an essential handbook for all primary care professionals professionals and a valuable reference for medical students and hospital physicians in training and in practice.

Essentials of Nursing Research (Paperback, Tenth, International Edition): Denise Polit, Cheryl Beck Essentials of Nursing Research (Paperback, Tenth, International Edition)
Denise Polit, Cheryl Beck
R1,286 Discovery Miles 12 860 Ships in 12 - 17 working days

The world's most widely used nursing research textbook, Essentials of Nursing Research, Tenth Edition equips students with everything they need to confidently apply research to nursing practice. AJN award-winning authors Denise Polit and Cheryl Beck clarify the language of nursing research and instill a practical understanding of nursing research fundamentals and the research process for both quantitative and qualitative studies - including design principles; sampling and data collection; criteria for assessing data quality; appraising the quality, rigor, and trustworthiness of studies; and approaches to understand the statistical results. This updated edition incorporates the latest clinical insights and approaches to research to familiarize students with increasingly important considerations in today's nursing practice, including the involvement of patients and stakeholders in translating research evidence to local settings; the appraisal of not only the rigor of research designs and methods but also the relevance and applicability of practice-based evidence; and the effective use of research in local quality improvement (QI) projects. UPDATED! Research insights reflect the latest, most relevant considerations for today's evolving nursing practice, including new coverage of quality improvement (QI) projects, clinical significance, comparative effectiveness research (CER), and systematic reviews. UPDATED! New organization simplifies the presentation of complex topics and better facilitates the use of research evidence in nursing practice. Clear, approachable writing makes difficult ideas easily digestible, even to students with no prior knowledge of technical terms. Critical Appraisal Guidelines walk students through studies and highlight aspects amenable to evaluation by research consumers. Research Examples and Critical Thinking Exercises emphasize important points and sharpen students' critical thinking skills. Tips help students confidently translate abstract notions of research methods into concrete applications. Colorful tables, figures, and examples engage students' attention and reinforce their understanding. Chapter Objectives emphasize essential information in each chapter. Key Terms familiarize students with common research terms. Bulleted Summary Points highlight key takeaways at a glance. Ensure a mastery of essential nursing skills and equip students for success throughout the nursing education continuum with the complete Essentials of Nursing Research, Tenth Edition solution: Lippincott (R) CoursePoint Study Guide for Essentials of Nursing Research, Tenth Edition

ABC of Quality Improvement in Healthcare (Paperback): T Swanwick ABC of Quality Improvement in Healthcare (Paperback)
T Swanwick
R895 Discovery Miles 8 950 Ships in 12 - 17 working days

Quality improvement (QI) is embedded in the fabric of successful healthcare organisations across the world, with healthcare professionals increasingly expected to develop and lead improvement as a core part of their clinical responsibilities. As a result, QI is rapidly becoming a feature of the education and training programmes of all healthcare professionals. Written and edited by some of the leading clinicians and managers in the field, ABC of Quality Improvement is designed for clinicians new to the discipline, as well as experienced leaders of change and improvement. Providing comprehensive coverage and clear, succinct descriptions of the major tools, techniques and approaches, this new addition to the ABC series demystifies quality improvement and develops a broader understanding of what constitutes quality in healthcare. With practical examples of improvement interventions and the common pitfalls that can befall them, this book will support and enable readers to manage change projects within their own organisations. Relevant to doctors, dentists, nurses, health service managers and support staff, medical students and doctors in training, their tutors and trainers, and other healthcare professionals at various levels, ABC of Quality Improvement will give readers the confidence to embark on their own improvement projects, whoever, and wherever they may be.

Bergey's Manual of Systematic Bacteriology - Volume 5: The Actinobacteria (Hardcover, 2nd ed. 2012): Aidan Parte Bergey's Manual of Systematic Bacteriology - Volume 5: The Actinobacteria (Hardcover, 2nd ed. 2012)
Aidan Parte; Edited by William B Whitman, Michael Goodfellow, Peter Kampfer, Hans-Jurgen Busse, …
R10,758 Discovery Miles 107 580 Ships in 10 - 15 working days

This updated final volume in the best-selling series of reference works features descriptions of more than 200 genera in 49 families and includes a revised taxonomic outline for the Actinobacteria as well as many medically and industrially important taxa.

Project Management for Drug Developers (Hardcover): Joseph P. Stalder Project Management for Drug Developers (Hardcover)
Joseph P. Stalder
R2,331 Discovery Miles 23 310 Ships in 9 - 15 working days

Project managers in drug development are the driving force behind the coordination of efforts. This book provides a practical reference for project managers in the pharmaceutical and biotech drug development industry, with the goal of assisting in creating an efficient and effective team structure and environment. The text details the role of project managers at each stage of drug development, the key interfaces that the PM will need to work closely with, and essential tools of the trade including frequently used techniques and methodologies. This book is useful for both entry-level and advanced-level PMs, as well as non-project managers from other functions. Features Includes authors' recent experience with improved tactics and technologies/software at various stages of drug development. Provides the most up-to-date and best practices, techniques, and methodologies in project management. Details the role of the PM at each stage of drug development, including working with the key interfaces throughout the process. Diverse audience including nonproject managers in clinical development, clinical operations, regulatory affairs, medical affairs, clinical pharmacology, and biostatistics. Provides templates and timelines for critical paths from development to commercialization and has potential as a textbook on relevant courses.

How to Read and Critique Research - A Guide for Nursing and Healthcare Students (Paperback): Helen Aveyard, Nancy Preston,... How to Read and Critique Research - A Guide for Nursing and Healthcare Students (Paperback)
Helen Aveyard, Nancy Preston, Morag Farquhar
R705 Discovery Miles 7 050 Ships in 12 - 17 working days

Do you find research challenging to read? Do you struggle to get to grips with a research paper? Understanding, critiquing and using research is a key requirement of students studying nursing and healthcare. This bookwill equip you with the skills you need to understand research and use it in your practice and academic assignments. The approach used in this book is unique: each chapter focuses on a published research paper - one you might be asked to read for a seminar or include in your academic work. In clear, straightforward language, the authors take you through each paper step by step, using it as a basis for exploring the underpinning research method or design, and how it has been reported. Key features: * Each chapter focuses on a different research method by working through a relevant research paper * Identifies the main skills you need for your course: understanding research methods and critiquing articles * Written specifically for nursing and healthcare students by experienced nursing and health care lecturers * Develops your confidence in understanding research by helping you to apply your knowledge to real research papers.

Clinical Immunology & Serology - A Laboratory Perspective (Paperback, 5th Revised edition): Linda E Miller, Christine... Clinical Immunology & Serology - A Laboratory Perspective (Paperback, 5th Revised edition)
Linda E Miller, Christine Dorresteyn Stevens
R2,829 R2,622 Discovery Miles 26 220 Save R207 (7%) Ships in 12 - 17 working days

The perfect balance of theory and practice! Here's the practical introduction you need to understand the essential theoretical principles of clinical immunology and the serological and molecular techniques commonly used in the laboratory. You'll begin with an introduction to the immune system; then explore basic immunologic procedures; examine immune disorders; and study the serological and molecular diagnosis of infectious disease. An easy-to-read, student-friendly approach emphasizes the direct application of theory to clinical laboratory practice. Each chapter is a complete learning module with learning outcomes, chapter outlines, theoretical principles, illustrations, and definitions of relevant terminology. Review questions and case studies help you assess your mastery of the material. A glossary at the end of the book puts must-know information at your fingertips. An access code inside new printed texts unlocks Lab Exercises and Branching Case Studies online at FADavis.com that offer more opportunities to apply theory to clinical laboratory practice.

Handbook of Analysis of Oligonucleotides and Related Products (Paperback): Jose V. Bonilla, G. Susan Srivatsa Handbook of Analysis of Oligonucleotides and Related Products (Paperback)
Jose V. Bonilla, G. Susan Srivatsa
R2,427 Discovery Miles 24 270 Ships in 9 - 15 working days

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.

The Whistle-Blower: The Life of Maurice Pappworth - the story of one man's battle against the medical establishment... The Whistle-Blower: The Life of Maurice Pappworth - the story of one man's battle against the medical establishment (Hardcover)
Joanna Seldon
R477 R394 Discovery Miles 3 940 Save R83 (17%) Ships in 9 - 15 working days

"No doctor, however great his capacity or original his ideas, has the right to choose martyrs for science or for the general good." Human Guinea Pigs: Experimentation on Man.Whistle-blowers tend not to be very popular. Maurice Pappworth's whistle was in the form of Human Guinea Pigs, the controversial book published in 1967 which examined unethical medical experimentation on humans and identified the researchers and institutions responsible. The ground-breaking text took the medical establishment by storm and provoked questions in Parliament. Brilliant, Jewish, already an outsider, Pappworth was recognised as the best medical teacher in the country. But convinced that the reason for these experiments being carried out was purely to advance the careers of ambitious practitioners, Pappworth had to speak up. In the wake of his expose, stricter codes of practice for human experimentation were put into place and the establishment of the research ethics committees was formed, which remains in place today. Maurice Pappworth's daughter, the late Joanna Seldon, re-assesses the importance of Human Guinea Pigs in her book Whistle-blower: The Life of Maurice Pappworth. She considers her father's text a major milestone in the development of current medical research ethics and demands a re-evaluation of the pioneering medical ethicist who compromised his own career in order to ensure the protection of the patient.

You Bet Your Life - From Blood Transfusions to Mass Vaccination, the Long and Risky History of Medical Innovation (Hardcover):... You Bet Your Life - From Blood Transfusions to Mass Vaccination, the Long and Risky History of Medical Innovation (Hardcover)
Paul A. Offit
R741 R617 Discovery Miles 6 170 Save R124 (17%) Ships in 10 - 15 working days
The Immortal Life of Henrietta Lacks (Paperback, Unabridged edition): Rebecca Skloot The Immortal Life of Henrietta Lacks (Paperback, Unabridged edition)
Rebecca Skloot 1
R366 R152 Discovery Miles 1 520 Save R214 (58%) Ships in 12 - 17 working days

Her name was Henrietta Lacks, but scientists know her as HeLa. Born a poor black tobacco farmer, her cancer cells - taken without her knowledge - became a multimillion-dollar industry and one of the most important tools in medicine. Yet Henrietta's family did not learn of her 'immortality' until more than twenty years after her death, with devastating consequences . . . Rebecca Skloot's fascinating account is the story of the life, and afterlife, of one woman who changed the medical world forever. Balancing the beauty and drama of scientific discovery with dark questions about who owns the stuff our bodies are made of, The Immortal Life of Henrietta Lacks is an extraordinary journey in search of the soul and story of a real woman, whose cells live on today in all four corners of the world.

Tamoxifen Tales - Suggestions for Scientific Survival (Hardcover): V.Craig Jordan Tamoxifen Tales - Suggestions for Scientific Survival (Hardcover)
V.Craig Jordan
R2,142 Discovery Miles 21 420 Ships in 12 - 17 working days

Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan's 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women's healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career.

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