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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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Adaptive Design Theory and Implementation Using SAS and R (Hardcover, 2nd edition)
Loot Price: R4,999
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Adaptive Design Theory and Implementation Using SAS and R (Hardcover, 2nd edition)
Series: Chapman & Hall/CRC Biostatistics Series
Expected to ship within 12 - 19 working days
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Get Up to Speed on Many Types of Adaptive Designs Since the
publication of the first edition, there have been remarkable
advances in the methodology and application of adaptive trials.
Incorporating many of these new developments, Adaptive Design
Theory and Implementation Using SAS and R, Second Edition offers a
detailed framework to understand the use of various adaptive design
methods in clinical trials. New to the Second Edition Twelve new
chapters covering blinded and semi-blinded sample size reestimation
design, pick-the-winners design, biomarker-informed adaptive
design, Bayesian designs, adaptive multiregional trial design, SAS
and R for group sequential design, and much more More analytical
methods for K-stage adaptive designs, multiple-endpoint adaptive
design, survival modeling, and adaptive treatment switching New
material on sequential parallel designs with rerandomization and
the skeleton approach in adaptive dose-escalation trials Twenty new
SAS macros and R functions Enhanced end-of-chapter problems that
give readers hands-on practice addressing issues encountered in
designing real-life adaptive trials Covering even more adaptive
designs, this book provides biostatisticians, clinical scientists,
and regulatory reviewers with up-to-date details on this innovative
area in pharmaceutical research and development. Practitioners will
be able to improve the efficiency of their trial design, thereby
reducing the time and cost of drug development.
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