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The Mammalian Egg Coat - Structure and Function (Paperback, Softcover reprint of the original 1st ed. 1989)
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The Mammalian Egg Coat - Structure and Function (Paperback, Softcover reprint of the original 1st ed. 1989)
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Publication of this monograph acknowledges great strides made in
research on the zona pellucida during the past decade or so. The
body of work presented testifies to a resurgence of interest in the
zona pellucida, prompted largely by a renewed appreciation of its
unique properties and its important functions during early mam
malian development. It is gratifying to realize that the zona
pellucida has at last achieved a well-deserved attention. Whereas
extracellular coats of nonmammalian eggs have been studied
intensively for many years, the zona pellucida by comparison, has
until now taken a back seat. Fortunately, the research presented
here signals an end to this situ ation. Many of the difficulties
inherent in working with relatively small amounts of material have
been overcome, paving the way for application of a wider variety of
experimental approaches to the zona pellucida by a larger community
of investigators. Hopefully, this monograph will serve as a
catalyst in this regard. As revealed in these pages, application of
contemporary experi mental methodologies has had significant impact
on both pure and applied research on the zona pellucida. For
example, modem im munological approaches have been used to assess
molecular fea tures of zona pellucida structure and function, as
well as to evalu ate the zona pellucida as a potential
contraceptive target antigen."
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