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Mucosal Delivery of Drugs and Biologics in Nanoparticles (Paperback, 1st ed. 2020)
Loot Price: R5,702
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Mucosal Delivery of Drugs and Biologics in Nanoparticles (Paperback, 1st ed. 2020)
Series: AAPS Advances in the Pharmaceutical Sciences Series, 41
Expected to ship within 10 - 15 working days
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Nanotechnology has revolutionized the approach to designing and
developing novel drug delivery systems. The last two decades have
seen a great interest in the use of nanotechnology to offer
efficient ways of delivering new and existing drugs and
macromolecules. The focus of this book is the application of
nanotechnology to deliver drugs and biological agents by the
mucosal routes of administration i.e. nasal, pulmonary, buccal, and
oral routes. It provides an overview of nanotechnology in drug
delivery with a description of different types of nanoparticles,
methods of preparation and characterization, and functionalization
for site-specific drug delivery. The emphasis is on the use of
nanoparticles in treating various cancers and infectious diseases.
It broadens the use of nanoparticles by including biologics,
including vaccines and immunotherapies, apart from drugs and
acknowledges the concerns around the potential toxicity of
nanoparticles to the host; several chapters will discuss the
biodistribution of these nanoparticles when mucosal routes of
administration are employed. Further, the interaction of
nanoparticles with the host's immune cells is discussed. Moreover,
it reviews the regulatory aspects of nanotechnology in product
development, especially when delivered by the mucosal route of
administration. Lastly, discusses the challenges and opportunities
to manufacture nanoparticles on an industrial scale. This book is
the first of its kind to focus on the design, development and
delivery of nanoparticles when administered by different mucosal
routes.
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