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Chlamydial Infections (Paperback)
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Chlamydial Infections (Paperback)
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1 2 Peter Reeve and Lavelle Hanna lSmith Kline & French
Laboratories, Research and Development, 709 Swedeland Road,
Swedeland, PA 19479, USA 2Department of Microbiology, S-412,
University of California, San Francisco, San Francisco, CA 94143,
USA Trachoma, an infectious keratoconjunctivitis due to chlamydial
infection, was one of the earliest recognized clinical entities.
References to it have been noted in Egyp- tian papyri and in
Greco-Roman medical treatises. Since those times it has remained a
most important eye infection, and indeed trachoma is still a major
cause of blindness in rural communities, affecting probably 6
million people (Dawson). The causal agent of trachoma was
identified by Halberstaeter and von Provazek in a much-quoted but
little-read paper published over 75 years ago. It was after the
isolation and demonstration of the growth of the causal agent of
trachoma, Chlamy- dia trachomatis, by Tang and his colleagues in
China in the late 1950s that there was an enormous increase in our
knowledge of these agents. The real explosion of knowledge and
interest in Chlamydia, however, has been in the last decade. With
the growing awareness of the extraordinary commonness of chlamydial
infections, not only in developing countries but also in the highly
developed countries, has come a considerable interest from all
areas concerned with medical science, from clinicians to molecular
biologists.
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