Translating Molecules into Medicines - Cross-Functional Integration at the Drug Discovery-Development Interface (Paperback, Softcover reprint of the original 1st ed. 2017)

Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies-this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	AAPS Advances in the Pharmaceutical Sciences Series, 25
Release date:	July 2018
First published:	2017
Editors:	Shobha N. Bhattachar • John S Morrison • Daniel R. Mudra • David M. Bender
Dimensions:	235 x 155 x 30mm (L x W x T)
Format:	Paperback
Pages:	461
Edition:	Softcover reprint of the original 1st ed. 2017
ISBN-13:	978-3-319-84303-2
Categories:	Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
LSN:	3-319-84303-6
Barcode:	9783319843032

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