Survival Analysis with Correlated Endpoints - Joint Frailty-Copula Models (Paperback, 1st ed. 2019)

This book introduces readers to advanced statistical methods for analyzing survival data involving correlated endpoints. In particular, it describes statistical methods for applying Cox regression to two correlated endpoints by accounting for dependence between the endpoints with the aid of copulas. The practical advantages of employing copula-based models in medical research are explained on the basis of case studies. In addition, the book focuses on clustered survival data, especially data arising from meta-analysis and multicenter analysis. Consequently, the statistical approaches presented here employ a frailty term for heterogeneity modeling. This brings the joint frailty-copula model, which incorporates a frailty term and a copula, into a statistical model. The book also discusses advanced techniques for dealing with high-dimensional gene expressions and developing personalized dynamic prediction tools under the joint frailty-copula model. To help readers apply the statistical methods to real-world data, the book provides case studies using the authors' original R software package (freely available in CRAN). The emphasis is on clinical survival data, involving time-to-tumor progression and overall survival, collected on cancer patients. Hence, the book offers an essential reference guide for medical statisticians and provides researchers with advanced, innovative statistical tools. The book also provides a concise introduction to basic multivariate survival models.

General

Imprint:	Springer Verlag, Singapore
Country of origin:	Singapore
Series:	JSS Research Series in Statistics
Release date:	March 2019
First published:	2019
Authors:	Takeshi Emura • Shigeyuki Matsui • Virginie Rondeau
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	118
Edition:	1st ed. 2019
ISBN-13:	978-981-13-3515-0
Categories:	Books > Science & Mathematics > Mathematics > Probability & statistics Books > Social sciences > Sociology, social studies > Social research & statistics > General
LSN:	981-13-3515-X
Barcode:	9789811335150

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!