Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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CpG Islands - Methods and Protocols (Hardcover, 1st ed. 2018)
Loot Price: R4,069
Discovery Miles 40 690
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CpG Islands - Methods and Protocols (Hardcover, 1st ed. 2018)
Series: Methods in Molecular Biology, 1766
Expected to ship within 12 - 17 working days
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This detailed volume examines bioinformatic and molecular
biological methods useful to identify and to explore the functions
of CpG islands, key navigation points to understand gene regulation
in fundamental processes such as development and cell
differentiation as well as in diseases like cancer. Beginning with
a historical perspective and important properties of CpG islands,
the book continues with sections on computational and wet lab
methods related to the study of DNA methylation, and in-depth
protocols for the analysis of CpG island functional features
including epigenetic profiling and chromatin interactions. Written
for the highly successful Methods in Molecular Biology series,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible protocols, and tips on troubleshooting and avoiding
known pitfalls. Authoritative and practical, CpG Islands: Methods
and Protocols aims to provide readers with the information and
methodologies necessary to continue to decipher how a genome's
structure and organization contribute to regulate biological
processes.
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