As ’n eietydse mediese speurder het die forensiese patoloog Ryan Blumenthal al derduisende outopsies uitgevoer wat tot die arrestasie van ’n groot aantal misdadigers gelei het. Dit is sy groot doel en strewe om oortreders aan die pen te help ry.

In Outopsietafel beskryf hy van die moeilike lesse wat hy as ’n jong patoloog moes leer en hy vertel van die ongewone en dikwels grusame sterfgevalle wat hy al teëgekom het. Hy het gedurende sy loopbaan byvoorbeeld al etlike hoëprofielsterftes hanteer, sterftes weens natuurrampe en ook mense wat deur weerlig of wilde diere gedood is.

Blumenthal bied ’n fassinerende blik op alles wat agter die skerms gebeur by die lykshuis. Al kan die dooies nie praat nie, het hulle nogtans baie om te sê – en Blumenthal is daar om te luister.

Locard’s Exchange Principle underpins all forensic science and holds that the perpetrator of a crime will bring something to the crime scene and leave with something from it.

Forensic experts use this principle daily to catch murderers and assailants. In Risking Life for Death, South African forensic pathologist Ryan Blumenthal offers a master class in this singular forensic technique based on real-life case studies. With more than twenty years’ experience in the field, Blumenthal explains how to look for clues and traces, and how what he does not find at autopsy is often more important than what he does find. In other words, the absence of evidence can sometimes be of greater value than the presence of evidence.

His account also highlights the dangers forensic pathologists are exposed to daily. As they try to unravel the puzzle of someone’s death, forensic pathologists often face life-threatening infections, toxic gases and the hazards associated with high-profile cases – in effect, risking their life to solve someone else’s death.

An understanding of Locard’s Exchange Principle can help you become a medical detective in your own life, can help you be a happier person and can even provide you with a better philosophy for growing older, Blumenthal argues.

The Fundamentals of Human Embryology covers embryonic development, with a unique focus on adult anatomy.

Its goal is to impart to students a comprehensive overview of how the human embryo forms, not only as a basis for the student of human anatomy, but also as a link to abnormalities they may encounter in their clinical careers. Extensively illustrated with labeled line drawings, now enlarged for better visibility, this concise manual will meet the needs of both undergraduate and postgraduate students in the Human Sciences.

In this Second Edition of the manual at the request of students and teachers, the authors have made the following changes:

• Increased the size of the diagrams
• Revised the text to comply with the Federative International Committee on Anatomical Terminology changes to the Terminologia Embryologica
• Altered the sequencing of some topics to allow the development to flow more logically
• Included an appendix of coloured photographs of congenital abnormalities to help students form a more realistic idea of developmental abnormalities.

The Atlas of X-Linked Intellectual Disability Syndromes is a comprehensive and up-to-date summary of the clinically distinctive disorders caused by genes on the X chromosome. Clinical and laboratory data on 150 syndromes are presented in a concise and consistent manner. Each syndrome is defined and information is provided on somatic features, growth and development, neurological signs, cognitive performance, imaging and other laboratory findings, and when possible, the nature and localization of the responsible gene. Craniofacial and other somatic findings are extensively illustrated. A differential matrix accompanies each syndrome description to assist the reader in identifying other X-linked syndromes with overlapping features. Individual syndrome entries are supplemented with nineteen appendices that identify syndromes with common features and provide the location or mapping limits and function of the responsible genes. The authors have extensive experience in the clinical and laboratory delineation of X-linked intellectual disability. They have described new syndromes, regionally mapped disease loci on the X chromosome, and identified the genes responsible for X-linked syndromes.

Genetics is in all senses a family affair. The diagnosis of a genetic condition affects not only the patient and biological family members who may themselves be at risk, but also "family" more generally as support may be sought from those considered kin and who may or may not be at risk themselves. It is considered best practice in genetic consultations to explore who will be informed within the family when a genetic condition or risk is diagnosed, particularly when the health of other family members is at risk. There is little guidance or consensus on how to achieve the implicit goal of informed family members while respecting patient confidentiality, however. There is a need for practitioners to be aware of the dynamics of family communication and to have guidance about how they may sensitively facilitate communication about genetics within families.
This handbook facilitates the development of clinical practices relating to family communication about genetics. Relevant theories of family communication are summarized and related to a clinical genetics milieu and, from this, frameworks for practitioners are presented. A book of this nature is particularly timely as the completion of the Human Genome Project will result in an unprecedented amount of information about genetic constitution and health risks becoming available to individuals and their families. The presence of a potential genetic condition in a family is not a new phenomenon. However, the growth in testing for genetic conditions, common complex conditions and variants that may influence health as well as drug metabolism means that a greater number of individuals will face decisions about communicating this information to their relatives. Many health professionals in all levels of health care will be confronted with issues of responsibility and practice in family communication about genetic information as they become providers of this testing.

Despite extensive physiological, biochemical, and structural studies, the mechanisms of muscle contraction operating in living muscle fibres are still not clearly understood. This book aims to describe and assess various experimental methods currently used in the field of muscle research. For
each method discussed, there is a comprehensive description of its advantages, problems, and limitations. Each chapter also contains a summary of the central results to have been obtained using each method. Comprehensively written by experts in their respective fields, this book will be of interest
to all investigators in muscle physiology.

Rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. This promises to offer unprecedented insights into the fundamental biological nature of ourselves and our species: where we came from, how we begin our lives, how we develop and grow, how we interact with our environment, how we get sick, how we get well, and how we age. Personal genomics is an essential component of the inevitable transition towards personalized health and medicine. As the medical establishment begins to explore and evaluate the role of personal genomics in health and medicine, both clinicians and patients alike will gain from becoming well versed in both the power and the pitfalls of personal genomic information. Furthermore, it is likely that all students of the biomedical sciences will soon be required to gain crucial understanding in the emerging field of personal genomics. Exploring Personal Genomics provides a novel, inquiry-based approach to the understanding and interpretation of the practical, medical, physiological, and societal aspects of personal genomic information. The material is presented in two parts: the first provides readers of all backgrounds with a fundamental understanding of the biology of human genomes, information on how to obtain and understand digital representations of personal genomic data, tools and techniques for exploring the personal genomics of ancestry and genealogy, discovery and interpretation of genetic trait associations, and the role of personal genomics in drug response. The second part offers more advanced readers an understanding of the science, tools, and techniques for investigating interactions between a personal genome and the environment, connecting DNA to physiology, and assessing rare variants and structural variation. This book aims to support undergraduate and graduate studies in medicine, genetics, molecular biology, and bioinformatics. Additionally, the design of the content is such that medical practitioners, professionals working in the biomedical sciences or related fields, and motivated lay individuals interested in exploring their personal genetic data should find it relevant and approachable.

Sex is a fundamentally important biological variable. Recent years have seen significant progress in the integration of sex in many aspects of basic and clinical research, including analyses of sex differences in brain function. Significant advances in the technology available for studying the endocrine and nervous systems are now coupled with a more sophisticated awareness of the interconnections of these two communication systems of the body. A thorough understanding of the current knowledge, conceptual approaches, methodological capabilities, and challenges is a prerequisite to continued progress in research and therapeutics in this interdisciplinary area.
Sex Differences in the Brain provides scientists with the basic tools for investigating sex differences in brain and behavior and insight into areas where important progress in understanding physiologically relevant sex differences has already been made. This book was edited and co-authored by members of the Isis Fund Network on Sex, Gender, Drugs and the Brain, sponsored by the Society for Womens Health Research.
The book is arranged in three parts. The first part of the book introduces the study of sex differences in the brain, with an overview of how the brain, stress systems, and pharmacogenetics differ in males and females and how this information is important for the study of behavior and neurobiology of both genders. The second part presents examples of sex differences in neurobiology and behavior from both basic and clinical research perspectives, covering both humans and nonhuman animals. The final part discusses sex differences in the neurobiology of disease and neurological disorders.
For interestedindividuals as well as those who are considering conducting research at the intersections of endocrinology, neuroscience, and other areas of biomedicine, the study of sex differences offers exciting and challenging questions and perspectives. This book is intended as a guide and resource for clinicians, scientists, and students.

In recent decades there has been an explosion in work in the social and physical sciences describing the similarities between human and nonhuman as well as human and non-animal thinking. This work has explicitly decentered the brain as the sole, self-contained space of thought, and it has found thinking to be an activity that operates not only across bodies but also across bodily or cellular membranes, as well as multifaceted organic and inorganic environments. For example, researchers have looked at the replication and spread of slime molds (playfully asking what would happen if they colonized the earth) to suggest that they exhibit 'smart behavior' in the way they move as a potential way of considering the spread of disease across the globe. Other scholars have applied this model of non-human thought to the reach of data mining and global surveillance. In The Biopolitics of Alphabets and Embryos, Ruth Miller argues that these types of phenomena are also useful models for thinking about the growth, reproduction, and spread of political thought and democratic processes. Giving slime, data and unbounded entities their political dues, Miller stresses their thinking power and political significance and thus challenges the anthropocentrism of mainstream democratic theories. Miller emphasizes the non-human as highly organized, systemic and productive of democratic growth and replication. She examines developments such as global surveillance, embryonic stem cell research, and cloning, which have been characterized as threats to the privacy, dignity, and integrity of the rational, maximizing and freedom-loving democratic citizen. By shifting her level of analysis from the politics of self-determining subjects to the realm of material environments and information systems, Miller asks what might happen if these alternative, nonhuman thought processes become the normative thought processes of democratic engagement.

The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace.
With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.

How women can improve their productivity, happiness, and physical well-being by keeping their natural cycles in mind and working with them (rather than ignoring them). In the Flo teaches women how to use their 28-day cycle to optimize their life by letting their internal clock and natural rhythms guide time management, diet, fitness, etc. (This is so simple and yet under-utilized it is shocking. It makes perfect sense when you think about it: You have different energy levels at different times of the month, different libido levels, etc. so why not use foresight to plan projects for when you are at your most effective, and understand when you need more emotional connection with others?) There are specific tips on what to eat and how to exercise depending on what phase you are in-and it works. Women are getting promotions, losing weight, and in one case thus far, literally clearing their endometriosis by using the cycle syncing method.

Eureka: Biochemistry & Metabolism is an innovative book for medical students that fully integrates core science, clinical medicine and surgery. The book benefits from an engaging and authoritative text, written by specialists in the field, and has several key features to help you really understand the subject: Chapter starter questions - to get you thinking about the topic before you start reading Break out boxes which contain essential key knowledge Clinical cases to help you understand the material in a clinical context Unique graphic narratives which are especially useful for visual learners End of chapter answers to the starter questions A final self-assessment chapter of Single Best Answers to really help test and reinforce your knowledge The book starts with a First Principles chapter which clearly explains the key concepts and mechanisms relevant to the study of medicine e.g. types of biochemical reaction, enzymes and cofactors. This is followed by a series of systems-based chapters which are introduced with an engaging clinical case which helps link the subject to the practice of medicine. Finally there is a self-assessment chapter consisting of 80 single best answer questions to test your understanding. The Eureka series of books are designed to be a 'one stop shop': they contain all the key information you need to know to succeed in your studies and pass your exams.

Functional Awareness: Anatomy in Action for Dancers is where anatomy meets artistry. Each chapter provides explorations in embodied anatomy in an engaging manner with the use of images, storytelling, and experiential exercises. It is an accessible introduction to the relationship between daily movement habits, dance training and anatomy. The information is founded on over 30,000 hours of experience teaching and training dancers to generate efficient exertion and appropriate recuperation. Functional Awareness: Anatomy in Action for Dancers employs somatic practices along with explorations in experiential anatomy to awaken the body-mind connection and improve movement function. The book applies the Functional Awareness (R) approach to improve dance technique and provide skills to enable the dancer to move with balance and grace in the classroom, on stage, and in daily life.

There are many modes of communication that neurons use to transmit information besides what has come to be called neurotransmission. Many of these other types of communication can be classified as neuromodulatory, where instead of conveying excitation or inhibition, the signal from one neuron changes the properties of other neurons or synapses. This form of neuronal communication is often overlooked by systems physiologists, but it is extremely prevalent in the nervous system and needs to be included in any description of how the nervous system processes information. This book provides the foundations for understanding the cellular and molecular basis for neuromodulatory effects. It illustrates some key examples of the roles played by neuromodulation in sensory processing, neuromuscular transmission, generation of motor behaviours, and learning. Finally, the book seeks to point out areas that are likely to be of importance in the future study of information processing by the nervous system. For neurobiology students and researchers, the book summarizes a vast amount of research, and puts it into the context of how these cellular mechanisms are used in systems of neurons. By spanning the levels of analysis from sub-cellular mechanisms through cellular properties and neuronal systems to behaviour, the book provides a framework for understanding this currently exploding field of research. It is accessible to anyone with a basic understanding of neurobiology, but is in depth enough to satisfy readers who are very familiar with the field.

The book Fertility SOS by Daminda Senekal-Griessel is for anyone who may be frustrated, at a loss and feeling unsure if having children is a realistic option. If you desire to start a family, but experience unexplained infertility, Polycystic ovary syndrome (PCOS), recurrent miscarriages, secondary infertility, or male factor infertility, then this book will give you a unique insight into understanding why this may be happening and how to solve it.

Infertility is not uncommon nowadays, with up to 20% of couples having difficulty conceiving. Male infertility is at an all-time high, with a 35 to 50 percent share of overall cases. Over-the-counter drugs, chronic medications, inadvertent exposure to dangerous pollutants, epigenetics, blood types and nutrition deficiencies, are some of the causes of infertility. Infertility also has significant negative social consequences for women who face social humiliation, mental anguish, sadness, anxiety, and low self-esteem because of their infertility. As a result, many of these women will go on to develop mental health problems. Increasing maternal age is linked to a higher incidence of miscarriage, which is assumed to be caused by low egg quality, which leads to chromosomal (genetic) abnormalities. In certain cases, the mother or father may have a minor genetic abnormality, but the baby may be more seriously damaged, resulting in miscarriage.

Assisted reproduction like IVF (In Vitro Fertilization) for example continues to remain inaccessible and unaffordable for most couples, especially in the current economic conditions we experience. Thus, people are increasingly turning towards more affordable, natural yet effective therapeutic assistance. It all starts with understanding your own health, what factors may be affecting your ability to conceive, and taking the appropriate steps to ensure a successful pregnancy. Following the guidance provided, will result in optimum fertility, fertilisation and optimal preparation of the uterus for implantation.

Not only do genes play a large role, but some medications can cause infertility and increase the risk of miscarriage. Couples will learn how to increase the health of eggs and sperm, and understand other variables such blood types, PH levels, mucous, hidden PCOS, and many other factors, influencing chances of procreating. Male infertility is also on the rise, so it is important to consider both partners potential influencing factors.

In addition to the book, FertilitySOS is launching Fertility Health Coaching sessions to offer guidance to couples struggling with infertility. By making use of the fertility coaching sessions, couples will achieve their goal to get their bodies into optimal reproductive health, with a tailored personal plan. The Fertility Health coach will uncover the possible root causes of individual cases of infertility.All sessions are available online www.fertilitysos.com

This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: * Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages * The genetics of Huntington's disease, including new information on its epidemiology discussions of new testing guidelines * Neurobiology, including recent insights into correlations between pathology and symptoms and a new chapter on neuronal circuitry * The molecular biology of Huntington's disease, including new chapters on the normal function of huntingtin, the molecular pathogenesis of Huntington's disease and the peripheral pathology of the disorder, and an extensively updated chapter on its structural biology * An updated description of the comprehensive care for Huntington's disease, featureing a new chapter on preclinical therapeutics and a completely rewritten chapter on the state of the art of experimental therapeutics and clinical trials.

This book summarizes the most recent data on the molecular and cellular mechanisms which determine the unique properties of nerve cells - their ability to differentiate, establish connections to each other, and to form the nervous system with its immense capability for receiving, analysing, and storing information about our external and internal world. The key role of calcium ions in this process is particularly explored, along with nervous system function in aging and neural pathology. The author, based at a high-profile research unit in the Ukraine, is able to draw on significant new research which has not been widely published. Plasticity in nerve cell function will be of interest to researchers and research students in the fields of neurophysiology, cellular physiology, biophysics, and neurochemistry in particular. It will also be of relevance to researchers and medical doctors interested in neuropathology and aging.

The best-selling author of Leonardo da Vinci and Steve Jobs returns. In 2012, Nobel Prize winning scientist Jennifer Doudna hit upon an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020, and make inheritable changes in the genes of babies. But what does that mean for humanity? Should we be hacking our own DNA to make us less susceptible to disease? Should we democratise the technology that would allow parents to enhance their kids? After discovering this CRISPR, Doudna is now wrestling these even bigger issues. THE CODE BREAKERS is an examination of how life as we know it is about to change - and a brilliant portrayal of the woman leading the way.

Complete, labeled illustrations of acupressure points in the human body.

From pre-teen to pre-med, this chart is loaded with beautifully illustrated diagrams, clearly and concisely labeled for easy identification.

Illustrations by award-winning medical illustrator Vince Perez.

Revised and updated: a user-friendly illustrated guide to human anatomy, written for students and practitioners This concise, pocket-sized guide is a full-color, on-the-go reference for students and practitioners of anatomy, massage, physical therapy, chiropractics, medicine, nursing, and physiotherapy. The Pocket Atlas of Human Anatomy, revised edition, interweaves text and images in a user-friendly and accessible way. Images have been critically assessed and modified from the previous edition for a highly reliable learning tool of bones, muscles, and nerves, plus all the other major body systems. A final chapter by Thomas W. Myers outlines The Anatomy Trains myofascial meridians, which presents a map of how tracks of fascial fabric wind longitudinally through series of muscles. This new approach to structural patterning has far-reaching implications for effective movement training and manual therapy treatment. Three appendices illustrate cutaneous nerve supply and dermatomes (Appendix 1), the major skeletal muscles, including detailed charts of the main muscles involved in movement (Appendix 2), and the remaining body systems (Appendix 3).

The best selling QuickStudy guide ever! This 6-page laminated guide contains 1,400 beautifully illustrated diagrams all clearly and concisely labeled for easy identification. Illustrations by award-winning medical illustrator Vince Perez.