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Books > Medicine > Pre-clinical medicine: basic sciences
Properly utilized interprofessional education will prepare students
in health professions to provide patient care in a collaborative
team environment. Once healthcare professionals begin to work
together in a collaborative interprofessional care team, patient
care is improved. Building a Patient-Centered Interprofessional
Education Program is a critical scholarly publication that provides
readers with practical strategies to facilitate building effective
interprofessional educational programs that both enrich learners
and help to improve patient care. Featuring a wide range of topics
including medical education, allopathic medicine, and telehealth,
this book is ideal for curriculum developers, instructional
designers, academicians, medical staff, teaching hospitals,
healthcare educators, researchers, healthcare professionals, and
students.
Clathrin-mediated endocytosis (CME) is a ubiquitous internalization
process in eukaryotic cells. It consists of the formation of an
approximately 50-nm diameter vesicle out of a flat membrane.
Genetics, biochemistry, and microscopy experiments performed in the
last four decades have been instrumental to discover and
characterize major endocytic proteins in yeast and mammals.
However, due to the highly dynamic nature of the endocytic assembly
and its small size, many questions remain unresolved: how are
endocytic proteins organized spatially and dynamically? How are
forces produced and how are their directions controlled? How do the
biochemical activities of endocytic proteins and the membrane shape
and mechanics regulate each other? These questions are virtually
impossible to visualize or measure directly with conventional
approaches but thanks to new quantitative biology methods, it is
now possible to infer the mechanisms of endocytosis in exquisite
detail. This book introduces quantitative microscopy and
mathematical modeling approaches that have been used to count the
copy number of endocytic proteins, infer their localization with
nanometer precision, and infer molecular and physical mechanisms
that are involved in the robust formation of endocytic vesicles.
At the heart of this classic, seminal book is Julian Jaynes's still-controversial thesis that human consciousness did not begin far back in animal evolution but instead is a learned process that came about only three thousand years ago and is still developing. The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion -- and indeed our future.
Progress and Challenges in Precision Medicine presents an
insightful overview to the myriad factors of personalized and
precision medicine. The availability of the human genome, large
amounts of data on individual genetic variations, environmental
interactions, influence of lifestyle, and cutting-edge tools and
technologies for big-data analysis have led to the age of
personalized and precision medicine. Bringing together a global
range of experts on precision medicine, this book collects
previously scattered information into one concise volume which
covers the most important developments so far in precision medicine
and also suggests the most likely avenues for future development.
The book includes clinical information, informatics, public policy
implications, and information on case studies. It is a useful
reference and background work for students, researchers, and
clinicians working in the biomedical and medical fields, as well as
policymakers in the health sciences.
In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F.
Massoud brings his considerable expertise to the topic of
Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge
is critical to reducing both overdiagnosis and misdiagnosis in
neuroimaging. This issue is part one of a two-part series on
neuroimaging anatomy that focuses on the brain, with each article
addressing a specific area. The issue also includes an article on
Brain Connectomics: the study of the brain's structural and
functional connections between cells. Contains 13 relevant,
practice-oriented topics including anatomy of cerebral cortex,
lobes, and the cerebellum; brainstem anatomy; cranial nerves
anatomy; brain functional imaging anatomy; imaging of normal brain
aging; and more. Provides in-depth clinical reviews on neuroimaging
anatomy of the brain and skull, offering actionable insights for
clinical practice. Presents the latest information on this timely,
focused topic under the leadership of experienced editors in the
field. Authors synthesize and distill the latest research and
practice guidelines to create clinically significant, topic-based
reviews.
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EmbryoGenetics
(Hardcover)
Simon Carlos, Rubio Carmen
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Nutritional Modulators of Pain in the Aging Population provides an
overview on the role of foods, dietary supplements, obesity, and
nutrients in the prevention and amelioration of pain in various
diseases in the aging population. Headaches, fibromyalgia, joint
pain, arthritis pain, back pain, and stomach pain are discussed. In
addition, the potential health risks of using foods to reduce
symptoms is evaluated. Each chapter reviews pain causing conditions
before reviewing the role of food or exercise. Both researchers and
physicians will learn about dietary approaches that may benefit or
harm people with various types of pain. Chapters include current
research on the actions of nutrients in pain treatment, the effects
of lifestyle and exercise on pain management, and discussions of
dietary supplements that provide pain relief from chronic
conditions like arthritis.
Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks
at the structure and function of tendons and ligaments. Biological
and synthetic biomaterials for their reconstruction and
regeneration are reviewed, and their biomechanical performance is
discussed. Regeneration tendons and ligaments are soft connective
tissues which are essential for the biomechanical function of the
skeletal system. These tissues are often prone to injuries which
can range from repetition and overuse, to tears and ruptures.
Understanding the biomechanical properties of ligaments and tendons
is essential for their repair and regeneration.
The content of medical education knowledge transfer is compounded
as medical breakthroughs constantly impact treatment, and new
diseases are discovered at an increasingly rapid pace. While much
of the knowledge transfer remains unchanged throughout the
generations, there are unique hallmarks to this generation's
education, ranging from the impact of technology on learning
formats to the use of standardized patients and virtual reality in
the classroom. The Handbook of Research on the Efficacy of Training
Programs and Systems in Medical Education is an essential reference
source that focuses on key considerations in medical curriculum and
content delivery and features new methods of knowledge and skill
transfer. Featuring research on topics such as the generational
workforce, medical accreditation, and professional development,
this book is ideally designed for teachers, physicians, learning
practitioners, IT consultants, higher education faculty,
instructional designers, school administrators, researchers,
academicians, and medical students seeking coverage on major and
high-profile issues in medical education.
Translating Epigenetics to the Clinic reviews current
methodological tools and experimental approaches used by leading
translational researchers seeking to use epigenetics as a clinical
model. It organizes epigenetics into disease treatment areas with a
major focus on oncology, and with much coverage of pervasive
treatment categories such as diabetes, as well as the 'diseases of
modernity'-including pharmacological addiction, dementia, and
ageing. Pedagogically, the work concentrates on the latest
knowledge, laboratory techniques, and experimental approaches used
by translational research leaders in this field. The book promotes
cross-disciplinary communication between the sub-specialties of
medicine. In common with the rest of the books in Translational
Medicine, the book remains unified in theme by emphasizing recent
innovations, critical barriers to progress, and the new tools being
used to overcome them. Also includes specific areas of research
that require additional study to advance the field as a whole.
Management of Infertility: A Practical Approach offers an accurate
and complete reference for the management of infertility and a
robust step-by-step guide for assisted reproduction technologies
(ARTs), including how to plan, design and organize a clinical
setting and laboratory. The book also provides an evidence-based,
complete and practical description of the available methods for
diagnosis and management of male and female infertility. This will
be an ideal resource for researchers, students and clinicians who
want to gain complete knowledge about both basic and advanced
information surrounding the diagnosis and management of infertility
and related disorders.
Research on dyneins has a direct impact on human diseases, such as
viruses and cancer. With an accompanying website showing over 100
streaming videos of cell dynamic behavior for best comprehension of
material, Dynein: Structure, Biology and Disease is the only
reference covering the structure, biology and application of dynein
research to human disease. From bench to bedside, Dynein:
Structure, Biology and Disease offers research on fundamental
cellular processes to researchers and clinicians across
developmental biology, cell biology, molecular biology, biophysics,
biomedicine, genetics and medicine.
Experimental Methods in Orthopaedic Biomechanics is the first book
in the field that focuses on the practicalities of performing a
large variety of in-vitro laboratory experiments. Explanations are
thorough, informative, and feature standard lab equipment to enable
biomedical engineers to advance from a 'trial and error' approach
to an efficient system recommended by experienced leaders. This is
an ideal tool for biomedical engineers or biomechanics professors
in their teaching, as well as for those studying and carrying out
lab assignments and projects in the field. The experienced authors
have established a standard that researchers can test against in
order to explain the strengths and weaknesses of testing
approaches.
Reinforce your understanding of the concepts in Patton's The Human
Body in Health & Disease! Corresponding to the chapters in the
text, this study guide reviews essential medical terminology,
concepts, and processes related to anatomy and physiology, and
explains how body systems function in health and disease. Each
chapter begins with a quick synopsis of the key points in the
textbook chapter. A variety of exercises make it easier to review
and apply key concepts, and labeling of anatomy drawings helps in
learning anatomical terms and structures. Know your Medical Terms
feature helps familiarize you with the various word parts used in
medical terminology and pairs nicely with the Language of Medicine
word lists in the main text to reinforce medical terminology
concepts that are key to understanding A&P. Brief synopsis of
core textbook concepts provides a comprehensive review of essential
content. Crossword Puzzles and Word Finds help you master new
vocabulary terms. Application Questions ask you to make judgments
based on the information in the chapter. Diagrams and labeling
exercises help reinforce where the structures of the body are
located. Matching and fill-in-the-blank exercises aid in
understanding chapter content. Answers to exercises are provided in
the back of the guide, along with references to the appropriate
textbook page and the textbook objective, so that you can easily
find where the material is presented. Study tips in the Preface
provide an overview of the most effective methods for learning and
retaining information.
Cancer Disparities, the latest in the Advances in Cancer Research
series, provides invaluable information on the exciting and
fast-moving field of cancer research. This latest volume presents a
broad introduction to a spectrum of factors contributing to cancer
disparities that include ancestral informative markers' role in
properly identifying race based on genetic ancestry, basic
biological pathways contributing to cancer disparities,
epidemiological factors linked to cancer disparities, and
social/behavioral factors influencing cancer disparities.
Enzymology at the Membrane Interface: Intramembrane Proteases,
Volume 584, the latest release in the Methods in Enzymology series,
covers a subset of enzymes that work in the environment of the
biological cell membrane. This field, called interfacial
enzymology, involves a special series of experimental approaches
for the isolation and study of these enzymes.
Chromatin Signaling and Diseases covers the molecular mechanisms
that regulate gene expression, which govern everything from
embryonic development, growth, and human pathologies associated
with aging, such as cancer. This book helps researchers learn about
or keep up with the quickly expanding field of chromatin signaling.
After reading this book, clinicians will be more capable of
explaining the mechanisms of gene expression regulation to their
patients to reassure them about new drug developments that target
chromatin signaling mechanisms. For example, several epigenetic
drugs that act on chromatin signaling factors are in clinical
trials or even approved for usage in cancer treatments,
Alzheimer's, and Huntington's diseases. Other epigenetic drugs are
in development to regulate various class of chromatin signaling
factors. To keep up with this changing landscape, clinicians and
doctors will need to stay familiar with genetic advances that
translate to clinical practice, such as chromatin signaling.
Although sequencing of the human genome was completed over a decade
ago and its structure investigated for nearly half a century,
molecular mechanisms that regulate gene expression remain largely
misunderstood. An emerging concept called chromatin signaling
proposes that small protein domains recognize chemical
modifications on the genome scaffolding histone proteins,
facilitating the nucleation of enzymatic complexes at specific loci
that then open up or shut down the access to genetic information,
thereby regulating gene expression. The addition and removal of
chemical modifications on histones, as well as the proteins that
specifically recognize these, is reviewed in Chromatin Signaling
and Diseases. Finally, the impact of gene expression defects
associated with malfunctioning chromatin signaling is also
explored.
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