Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function of hormones from basic biology to clinical use, offering a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors, signaling pathways, and the biological activities they regulate. The book's stellar editorial board, affiliated with the Japan Society for Comparative Endocrinology, brings together authors that present a compelling structure of each hormone with a consistent presentation that provides a primer surrounding the plethora of hormones that now exist. Comparative endocrinology continues to rapidly expand and new information about hormones is being produced almost daily, making it important to stay up-to-date. Hormone, paracrine, and autocrine factors have been identified as key players in a range of different systems, including immune, musculoskeletal and cardiovascular. Frontiers between disciplines are being blurred and many scientists in fields other than endocrinology are interested in hormones. Scientists now have the unprecedented opportunity to look from invertebrates to vertebrate and identify novel regulatory factors and understand their function and how they determine an organism's physiology and survival.

Key features: * Provides a clear explanation for many of the pain generators in low back pain and illuminate this perplexing and ubiquitous problem. * Addresses a gap in the existing literature, as "non-specific" or mechanical lumbosacral spine pain accounts for by far most chronic spinal pain sufferers' complaints for clinicians dealing with spinal pain syndromes like general medical practitioners, and spinal specialists in various fields such as sports medicine. * Illustrates anatomical structures that can be injured and thus become responsible for causing mechanical lumbosacral spine pain, frequently, such injuries cannot be detected on sophisticated imaging such as MRI.

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.

At the heart of this classic, seminal book is Julian Jaynes's still-controversial thesis that human consciousness did not begin far back in animal evolution but instead is a learned process that came about only three thousand years ago and is still developing. The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion -- and indeed our future.

Make difficult pathophysiology concepts come to life! Filled with vibrant illustrations, simplified language, and detailed online content Understanding Pathophysiology, 7th Edition delivers the most accurate information on treatments, manifestations, and mechanisms of disease across the lifespan. This new edition is fully revised and includes coverage of rare diseases and epigenetics to you with a thorough understanding of conditions affecting the human body. Plus, with over 30 new 3D animations on the companion Evolve site, quick check boxes at the end of each chapter, and disease progression algorithms, this text helps you engage with the fundamental knowledge you need to succeed in nursing school and in practice. Student resources include animations, review questions, answers to the Quick Check boxes (featured in the text), chapter summary reviews, and case study with answers for select chapters. Algorithms throughout the text clarify disease progression. Did You Know boxes highlight new developments in biologic research, diagnostic studies, preventive care, treatments, and more. Quick Check boxes tests your retention of important chapter concepts. Risk Factor boxes alert you to important safety considerations associated with specific diseases. Summary Review sections provide fast, efficient review of chapter content. Geriatric Considerations boxes and Pediatric Considerations boxes highlight key considerations for these demographics in relevant chapters. Consistent presentation helps you to better distinguish pathophysiology, clinical manifestations, and evaluation and treatment for each disease. Glossary of approximately 1,000 terms familiarizes you with the most difficult or important terminology related to pathophysiology. NEW! Chapters on Alterations in Immunity and Obesity and Disorders of Nutrition feature the latest coverage of these hot topics. NEW! Additional coverage of rare diseases and epigenetics gives you a comprehensive understanding of conditions and cell growths that affect the human body. NEW! Streamlined content and illustrations ensures content is at an appropriate level for undergraduate students. NEW! More than 1000 illustrations in the text and 30+ new 3D animations on companion Evolve site bring difficult concepts to life for a new perspective on disease processes.

Instant Anatomy presents anatomy and anatomical relationships in a simple, unique, schematic manner to aid the speedy understanding and retrieval of anatomical facts. It shows structures such as nerves and blood vessels in their entirety, unlike the partial, regional presentations given in most textbooks. Covering the major aspects of anatomy, each section presents the relevant structures in double page spreads, with clear, full-colour diagrams on the left and concise text for each structure on the right. This new fifth edition includes more surface anatomy such as new myotome maps, bones of the hands and feet, principles of movement at shoulder and hip and images to clarify the understanding of the inguinal region and the lesser sac of the stomach. Ideal for use alongside a core anatomy textbook, Instant Anatomy is the perfect quick reference guide for medical students, surgeons, radiologists and those in many other specialties. The companion website at www.instantanatomy.net with its podcasts and wide ranging multiple choice questions provide invaluable exam preparation.

Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers.

Lippincott (R) Connect Featured Title Purchase of the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Praised by faculty and students for more than two decades, Lippincott (R) Illustrated Reviews: Biochemistry is the long-established go-to resource for mastering the essentials of biochemistry. This best-selling text helps students quickly review, assimilate, and integrate large amounts of critical and complex information, with unparalleled illustrations that bring concepts to life. Like other titles in the popular Lippincott (R) Illustrated Review Series, this text follows an intuitive outline organization and boasts a wealth of study aids that clarify challenging information and strengthen retention and understanding. This updated and revised edition emphasizes clinical application and features new exercises, questions, and accompanying digital resources to ready students for success on exams and beyond. NEW! Clinical Application boxes train students to confidently apply biochemistry in clinical scenarios. NEW! Cross-references to other Lippincott (R) Illustrated Reviews titles help students grasp how biochemical concepts relate to other basic sciences. UPDATED! Vibrant illustrations and detailed tables clarify complex biochemical concepts. NEW and UPDATED! Study Questions and Answers for each chapter test students' retention and strengthen their test-taking confidence. UPDATED! Integrative Case Studies with Review Questions familiarize students with commonly encountered clinical scenarios and alert them to potential widespread implications of presenting issues. NEW! Animations enhance students' understanding of biochemical concepts and processes with vivid detail and accuracy. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

The treatment of cancer in young women and men is increasingly turning from focusing purely on survival to a recognition of the long-term effects of treatment on subsequent quality of life. In this regard, fertility is a very high priority for patients. This is the first book to explain the latest techniques in fertility preservation. Chapters cover fertility preservation in both women and men, management of cancer in pregnancy, egg donation and surrogacy, hormone replacement options, counselling and ethical issues. A multidisciplinary team of over 60 specialists were involved in this work, with contributions from leading obstetricians, medical oncologists, gynaecological oncologists, urologists and fertility specialists. The book is formally supported by the Association of Cancer Physicians (ACP). This highly patient-centred, readable text will be of value to a wide range of clinicians and physicians, and doctors in training, in their daily work.

 The Anatomist's Library is a fascinating chronological collection of the best anatomical books from six centuries, charting the evolution of both medical knowledge and illustrated publishing. There is a rich history of medical publishing across Europe with outstanding publications from Germany, France, Italy, Netherlands, Spain, UK, and also many from Persia and Japan.   Because of the high value of accurate medical textbooks, it was these works that pushed the boundaries of illustrated publishing. They commanded the expert illustrators and skilled engravers and hence didn’t come cheaply. They were treasured by libraries and their intrinsic worth has meant that there is an incredible wealth of beautifully preserved historic examples from the 15th century onwards   The enduring popularity of Gray’s Anatomyhas shown that there is a long-term interest in the subject beyond the necessity of medical students to learn the modern equivalent – the 42nd edition (2020) – from cover to cover. But Englishman Henry Gray was late in the field and never saw the enduring success of his famous work. Having first published the surgeon’s reference book in 1858, he died in 1861 after contracting smallpox from his nephew (who survived). He was just 34.   Gray was following on from a long tradition of anatomists starting with Aristotle and Galen whose competing theories about the human body dominated early medicine. However they did not have the illustrative skills of Leonardo da Vinci who was trained in anatomy by Andrea del Verrocchio. In 1489 Leonardo began a series of anatomical drawings depicting the human form. His surviving 750 drawings (from two decades) represent groundbreaking studies in anatomy. However none of Leonardo's Notebooks were published during his lifetime, they only appeared in print centuries after his death.   Brussels-born Andries van Wesel (Andreas Vesalius) professor at the University of Padua is deemed to be the founder of modern anatomical reference with his 1543 work De Humani Corporis Fabrica Libri Septem ("On the fabric of the human body in seven books"). An Italian contemporary was Bartolomeo Eustachi who supported Galen’s medical theories. Among other discoveries he correctly identified the Eustachian tube and the arrangement of bones in the inner ear. His Anatomical Engravings were completed in 1552, nine years after Vesalius’s great work, but remained unpublished until 1714.   These are just two entries in a book brimming with an abundance of important illustrated works – with some more primitive examples from the 15th century, up to the 42nd edition of Gray’s in the 21st.  

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications-trends that have recently become a serious problem. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, this latest volume compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Key Features: Explains reliable and tested protocols for the preparation of intermediates for carbohydrate synthesis Offers a unique resource in glycosciences, compiling useful information in one reference Presents protocols that are of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops Explores synthetic carbohydrate chemistry from both the academic and industrial points of view Guarantees the reader a good, clean, reproducible experiment

The United Nations Madrid International Plan of Action on Ageing (MIPAA) offers a bold new agenda for handling the issue of ageing in the 21st-century. It focuses on three priority areas: older persons and development; advancing health and well-being into old age; and ensuring enabling and supportive environments. This book brings together global perspectives on the MIPAA and focusses on and assesses the success and failures of governments to implement its recommendations. Despite its pivotal importance in international ageing policy, the MIPAA has been relatively neglected by academics in their writings and studies. This book mitigates this analytical and empirical cavity. Each chapter focuses on one specific geographical region and addresses five key themes: National ageing situation; Twenty years of MIPAA; Ensuring ageing with dignity; Healthy and active ageing in a sustainable world; and Priorities for the future. It presents an overall summary of the findings, future challenges and opportunities related to ageing, recommendations for future actions to be taken, and policy adjustments needed. The authors also present lessons that were learnt from managing the impact of COVID-19 on older people, together with an outlook on the most immediate priorities for the future so that the recommendations in the MIPAA are achieved in post-COVID-19 and sustainable ethical scenarios. An important contribution towards the advancement of ageing policy, the book will be indispensable to students and researchers of gerontology, ageing, and health. It will also be of interest to policy makers, geriatricians, dementia care specialists, social policy makers responsible for ensuring active and healthy ageing, and all public sector departments which have specific responsibilities towards improving the quality of life of older adults.

Complete, labeled illustrations of acupressure points in the human body.

From pre-teen to pre-med, this chart is loaded with beautifully illustrated diagrams, clearly and concisely labeled for easy identification.

Illustrations by award-winning medical illustrator Vince Perez.

A much-needed overview of the available information now accumulating to indicate that assisted reproductive technologies are generally safe for both babies and mothers. However, the literature abounds with reports of a higher risk of obstetric and perinatal complications; regarding the long term outcomes for both women and children, the data are still scarce. The chapters summarized in this book review the current knowledge on long term safety of assisted reproduction and indicate the need for continued research to cover the lack of data in some specific patient groups and for recently developed treatments that only have a short period of follow-up.

What happens when two intelligent and highly informed fictional college students, one strongly pro-choice and the other vigorously pro-life, are asked to put together a presentation on abortion? Their conversations over five days - friendly but lively, charitable but clear - are captured in this book. Through these dialogues, students and other interested readers are introduced to the difficult moral issues of abortion. In Chapter 1, readers learn about Roe v. Wade and other relevant legal cases. Chapter 2 covers basic, philosophical issues such as: What is a person? Are fetuses persons? Is fetal potential morally relevant? How shall we define the moral community? Chapter 3 introduces students to Don Marquis's "Why Abortion is Immoral" and also the metaphysical issues of personal identity and its relevance to abortion. Chapter 4 covers Judith Jarvis Thomson's "A Defense of Abortion", including objections and responses to the argument from bodily autonomy. Finally, Chapter 5 looks at abortion in hard cases, such as in cases of rape, fetal disability, non-viable pregnancies, and sex-selection; the chapter also includes a conversation on fathers and abortion. With a Foreword by Laurie Shrage, topics headings in the margins, and an annotated bibliography, Dialogues on the Ethics of Abortion is an easy-to-use volume and valuable resource for anyone interested in a fair and clear-headed approach to one of the most contentious moral issues of our time.

Psychiatry and clinical psychology have long been divided about the roles of nature and nurture in the pathways to psychopathology. Some clinicians offer treatment almost entirely based on neuroscience. Some psychologists offer psychotherapies almost entirely based on the impact of environmental stressors. Paris argues for a balanced middle ground between nature and nurture in human development. This book reviews and integrates research showing that the key to understanding the development of mental disorders lies in interactions between genes and environment. It explores why personality is a key determinant of how people respond to stress, functioning as a kind of psychological immune system. This model represents a shift from overly simple and reductionistic constructs, based primarily on biological risks or on psychosocial risks in development. Instead, it offers a complex and multivariate approach that encourages a broader approach to treatment. This book is essential for all mental health clinicians who are interested in understanding the roles of nature and nurture in the development of psychopathology.

Prenatal screening for genetic disorders is becoming an increasingly widespread phenomenon across the globe. While studies have highlighted the importance of women's experiences of such screening, little is known about men's roles and direct involvement in this process. With a focus on the experiences of both women and men, this text offers an innovative and passionate account of the gendered nature of prenatal screening. Drawing on interview data with pregnant women and their male partners in a UK city, Reed provides a compelling analysis of maternal and paternal roles in prenatal screening. Through this analysis, the book raises important issues around genetics, gender and screening practice. With a focus on the gendered production of 'good' and 'bad' genes, the book explores differences between visual technologies and blood screening. It also explores the gendered nature of genetic responsibility and the impact this has on parenting roles. Extending its arguments into other key debates in prenatal genetics - including a focus on the impact of screening on other types of stratification, including ethnicity and class - Reed provides an original and comprehensive analysis of some of the most pressing concerns in the field to date. This book will be of interest to students and scholars of the sociology of health and illness, science and technology studies, gender studies, feminist bioethics and medical anthropology, as well as professionals in the fields of midwifery and genetic counselling.

Provides students and researchers comprehensive, vital and robust guidelines for clinical sport testing. The new edition provides an increased coverage of special populations compared with the previous edition reflecting the increasing importance of the area Brings together internationally recognised and BASES accredited experts for each section

Exercise Physiology for Health and Sports Performance brings together all the essential human anatomy and applied physiology that students of exercise science, physical education and sports coaching need to know.

Written in a friendly, accessible style and containing a wide range of features to help develop understanding, this book provides a complete one-stop-shop for exercise physiology.

Sickle cell and thalassaemia are among the world's most common genetic conditions. They are especially common in Africa, Brazil, the Caribbean, the Middle East and Asia. They affect all ethnic groups but they particularly impact on minority ethnic groups in North America, Europe and Australasia. Much research has focused on clinical, laboratory and genetic studies of these conditions. Through a wide-ranging selection of readings based on social scientific research into sickle cell and thalassaemia, this book seeks to redress this imbalance. This is important as, through an examination of the different social, economic and cultural contexts of the lives of people living with sickle cell or thalassaemia, the contributors demonstrate that people are more than the sum of their genes and that their life experiences are rarely derived solely from the clinical severity of their condition but depend on the social context of their lives. Genetics and Global Public Health presents a new concluding chapter which highlights the critical nature of social science research for sickle cell and thalassaemia communities, providing key insights into the social contexts of human behaviour and analysing how societal arrangements could change to assist people living with either condition. It will be of great interest to postgraduate and research students as well as professionals working in the field of public health. This book was originally published as a special issue of the journal Ethnicity and Health.

This book discusses the European Union's approach to governance reform in its development assistance relationships with various groups of developing countries. A group of expert authors outline the general features of the position on governance taken by the EU, which is currently the major multilateral donor of development assistance, and discuss the implementation of EU policies in a set of cases: the group of African, Caribbean and Pacific (ACP) states, the New Partnership for Africa's Development (NEPAD), Southeastern Europe, Central Asia, the Euro-Mediterranean, Latin America and fragile states. The contributions to the book argue that the EU's position on governance reform, particularly since the adoption of the European Consensus on Development in 2005, has had distinctly neoliberal overtones. The EU's governance-related strategies have been instrumental to deepening market-based reform in aid-receiving countries. Policies on state-building adopted by the EU reflect mainly the interests of and ideas embraced by the EU and its member states. To an important extent, the rhetoric accompanying EU policies does not match with the political and social dynamics inherent in governance structures on the ground in many of its aid-recipient partner countries. This book was published as a special issue of Third World Quarterly.

Examining the chemical modification of biological polymers and the emerging applications of this technology, Chemical Modification of Biological Polymers reflects the change in emphasis in this subsection of biotechnology from the study of protein structure and function toward applications in therapeutics and diagnostics.

Highlights

• The basic organic chemistry of the modification proteins, nucleic acids, oligosaccharides, polysaccharides, and their applications
• New analytical technologies used to characterize the chemical modification of biological polymers
• Identification of in vivo, non-enzymatic chemical modification of biological polymers
• Specific chemical modifications to generate biopharmaceutical products

This book covers the basics on the organic chemistry underlying the chemical modification of biopolymers, including updates on the use of various chemical reagents. It describes the current status of chemical modification of biological polymers and emerging applications of this technology in biotechnology. These technologies are important for the manufacture of conjugate proteins used in drug delivery, for the preparation of nucleic acid microarrays, and for the preparation of hydrogels and other materials used in tissue engineering.

Children and Exercise XXVII presents the latest scientific research into paediatric sport and exercise science and medicine including contributions from a wide range of leading international experts and early career researchers. The book begins with chapters devoted to the 5 invited keynote lectures followed by forty-two of the peer-reviewed presentations which are arranged into five thematic sections addressing:

• Exercise physiology
• Physical activity and health
• Exercise and medicine
• Testing and performance
• Young athlete and sports participation.

The forty-seven chapters offer a review of current topics and ongoing research in paediatric sport and exercise science and medicine. The book is therefore a key text for all researchers, lecturers, paediatricians, health professionals and students with an interest in the exercising child in health and disease.