Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility provides cutting-edge information and solutions to help support the worldwide rise of fertility challenges. It addresses common, yet not commonly known, root-causes of oxidative stress that are at the heart of reproductive issues (and all chronic health issues). These solutions can help enhance the outcomes of Assisted Reproductive Technologies (ART) or support women to avoid them altogether. Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility will show you how to improve cell health (including egg and sperm), lower inflammation, balance nervous system functioning, and optimize genetic expression, allowing the body to return to its naturally fertile state. It details information on numerous root causes of health-derailing inflammation and oxidative stress, while the appendices discuss the genetic and biochemical pathways related to these topics. Each chapter also provides easy "Action Steps" that can be implemented immediately. Chapter topics include iron dysregulation; oxalates; mold/mycotoxins; phase 2 liver detoxification pathways; fat utilization; introductory information on genetics, epigenetics, and nutrigenomics; everything one needs to know about histamine intolerance; and how these factors adversely affect metabolic and reproductive functions. Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility is the handbook for people wanting to achieve and sustain a healthy pregnancy. It highlights lesser-known causes of fertility challenges the reader can learn how to investigate. This book also serves as a reference guide for practitioners, providing them with additional tools to add to their repertoires when other protocols have not been effective. It may also provide clarity as to why other protocols did not work, and will enable the practitioner to custom-tailor protocols for each patient.

Despite the gains of the women's movement, women are still judged by what they look like--and men, by what they do. Fat--A Fate Worse Than Death? offers hardy resistance to the narrow, random, and irrational appearance standards set for American women through an approach that is personal, eclectic, courageous, and funny. If you are interested in giving up your diet, throwing out your scales, and concentrating on who you are on a deeper level, this book will show you how to accept, appreciate, and even love your body Using statistics, research, anecdotes, and personal experiences, Fat--A Fate Worse Than Death? explores how appearance standards have built a prison for women. With the book's helpful advice, reading suggestions, and list of more than 100 ways to fight looksism, sexism, ageism, and racism, you will learn to express your rights and needs, regardless of your shape or size, and tear down those prison walls. Designed to transcend the boundaries between the personal and the political, Fat--A Fate Worse Than Death? discusses: examples of how weight and size constitute the last socially accepted prejudice the national "War on Fat" counteracting societal influences that support weight preoccupation connection between appearance standards for older women and large women nurturing your body resisting male-defined standards of beauty for women the myth of diets and dieting how the body resists weight loss how women are disempowered by concentration on weight and appearance how concentrating on appearance leaves real-life issues unaddressed how feeling bad about yourself can turn you into a willing consumerFeminists, faculty and students of women's studies programs, aging women, women of radical politics, and other concerned women and men will find that Fat--A Fate Worse Than Death? states explicitly how women are kept powerless by subscribing to cultural and social edicts on physical appearance. Don?t live silently in a society that degrades and discounts women because of their physical stature and don?t let obsession with thinness keep you passive, docile, and unable to give your energy to things that really need your passion and intelligence. Read this book and learn to not only value yourself for who you are, but also to counteract American culture's equality-denying prejudices and practices.

Rapid regeneration of city areas has placed the quality of urban design high on public and policy agendas worldwide. This work examines the achievement of quality in the urban environment, in a planning context. Tracing urban design from its roots, the authors draw on both historical and current practices to examine the key physical, political and economic forces at play and the social pressures and impacts brought about by both failures and achievements in urban design. This illustrated critique of towns and cities draws on examples from across Western Europe, South Africa and USA to examine both public and private sector development practices, controls and fiscal policies within a diverse range of localities. The authors indicate the need for a reinstitution of region-provincial approaches, for closer co-ordination bewteen sectors, and revised fiscal policies in planning and development in order to enhance the quality of urban social experience and environments.

Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.

The current popular and scientific interest in virtual environments has provided a new impetus for investigating binaural and spatial hearing. However, the many intriguing phenomena of spatial hearing have long made it an exciting area of scientific inquiry. Psychophysical and physiological investigations of spatial hearing seem to be converging on common explanations of underlying mechanisms. These understandings have in turn been incorporated into sophisticated yet mathematically tractable models of binaural interaction. Thus, binaural and spatial hearing is one of the few areas in which professionals are soon likely to find adequate physiological explanations of complex psychological phenomena that can be reasonably and usefully approximated by mathematical and physical models. This volume grew out of the Conference on Binaural and Spatial Hearing, a four-day event held at Wright-Patterson Air Force Base in response to rapid developments in binaural and spatial hearing research and technology. Meant to be more than just a proceedings, it presents chapters that are longer than typical proceedings papers and contain considerably more review material, including extensive bibliographies in many cases. Arranged into topical sections, the chapters represent major thrusts in the recent literature. The authors of the first chapter in each section have been encouraged to take a broad perspective and review the current state of literature. Subsequent chapters in each section tend to be somewhat more narrowly focused, and often emphasize the authors' own work. Thus, each section provides overview, background, and current research on a particular topic. This book is significant in that it reviews the important work during the past 10 to 15 years, and provides greater breadth and depth than most of the previous works.

With the use of crack on the rise in American cities, there is more need than ever to understand the biological, environmental, and social factors behind cocaine addiction, as well as the pharmacological properties of cocaine that make it such an addictive drug. The Neurobiology of Cocaine Addiction helps clinicians and researchers analyze research findings and their relevance to the clinical treatment of cocaine dependency. To do this, it looks at the whole spectrum of cocaine use, from trends in cocaine-involved deaths, hospital emergencies, arrests, and treatment admissions to the specific impact the drug has on brain function. The book reports on important findings from positron emission tomography (PET) and a "binge" pattern cocaine administration mode. This will enable you to improve your understanding of how cocaine alters the pleasure/reward system of the brain and creates new instinctual needs that displace the inherent instinctual needs of hunger and sex.By reading The Neurobiology of Cocaine Addiction, you will sharpen your knowledge of the basic actions of cocaine, the factors related to daily cocaine use, the neurobiological basis of addictive diseases, and drug-induced alterations in normal physiology. You will also learn about: the coexistence of cocaine and heroin addiction cocaine's disruption of the endogenous opioid system QEEG and how it can play a potentially useful role in drug development and planning hypotheses of sensitization in the pathophysiology of cocaine dependence factors that predict daily cocaine use among patients in a methadone maintenance program abnormalities in brain function that persist for up to six months after last cocaine use patterns of cocaine use the importance of prospective data analysis and the limitations of a self-selective study groupClinicians, researchers, psychiatrists, and other professionals in chemical dependency and narcotics rehabilitation will turn the last page of The Neurobiology of Cocaine Addiction with a better understanding of cocaine's addictive qualities and the characteristics of the individuals who become addicted to it. You will see what headway has been made in research at some of the nation's top laboratories, but you will also see what remains to be done. Hopefully, you will find where you can make a contribution either at the practical level, the research level, or both.

Carefully delineating each step in the formation of the lung, Lung Growth and Development examines prenatal and postnatal lung development...the regulation of surfactant protein gene expression and models for the analysis of epithelial gene transcription and function...cellular differentiation and the role of mesenchymal cells...airway gland growth and differentiation...growth regulation in the tracheobronchial epithelium and mucociliary differentiation...embryonic precursors of the pulmonary nervous system and the development of lung innervation...Clara cells, airway smooth muscle development, cell interactions in vessel formation, and the surfactant system...respiratory distress syndrome, bronchopulmonary dysplasia, and compensatory lung growth...and more. Written by over 30 international experts, Lung Growth and Development is a practical guide for pulmonologists and pulmonary disease specialists, physiologists, molecular and cellular biologists, pathologists, neonatalogists and pediatricians, anatomists, pathologists, and graduate-level and medical school students in these disciplines.

Conceived at a time when biological research on aggression and violence was drawn into controversy because of sociopolitical questions about its study, this volume provides an up-to-date account of recent biological studies performed -- mostly on humans. A group of scientists recognized the importance of freedom of inquiry and deemed it vital to address the most promising biological research in the field. The focus on biological mechanisms is not meant to imply that biological variables are paramount as a determinant of violence. Rather, biological variables operate in conjunction with other variables contributing to aggression or violence, and a complete understanding of this phenomenon requires consideration of all influences bearing on it.
This book will familiarize readers with the rapidly growing and increasingly significant body of knowledge on the biological bases of human antisocial, aggressive, and violent behaviors. The editors concentrated on biological influences that support the basic physiological and biochemical processes of the brain and did not cover those biological influences that impact on the health of the individual such as head injury, pregnancy and birth complications, diet, and exposure to lead and other toxins. They focused on biological influences to illuminate their role in the complex behavioral phenomenon of violence.
Three different approaches to the biological study of human antisocial, aggressive, and violent behaviors are represented -- genetic, neurobiological, and biosocial. Representing each of these three approaches, individual chapters from investigators in psychobiology, biological psychiatry, and basic-clinical neurosciences address the most recent experimental findings, methods, theory, and common misconceptions in the biological study of aggression and violence. The areas of primary focus are behavior and molecular genetics, neurochemistry and hormones, neuroimaging, psychophysiology and developmental psychobiology. Generally speaking, investigators following these different approaches have experience in different scientific backgrounds, select different methods, generate different analyses, employ different conceptual definitions for some of the same terms, and assume a different philosophical stance in attempting to explain violence. Nevertheless, all are united in their efforts to understand the biological underpinnings of violence. This book then assumes a comprehensive approach wherein different levels of analysis and different approaches inform each other. It is clear from the studies reported that aggression and violence are multidetermined phenomena and understanding them requires an interdisciplinary approach spanning economic, sociopolitical, psychological, sociological, and criminological as well as biomedical considerations. Nature (biology) and nurture (experience, context) are fundamentally inseparable in explaining aggression and violence; biology may affect experience or context, but experience or context also influences biology. Both need to be studied in a search for explanations of this phenomena.

There is renewed interest in lifestyle medicine - the focus on food, physical activity, stress management, high-quality connections, restorative sleep, and avoidance of toxic substances - in the prevention, treatment, and sometimes reversal of chronic disease, but very little information exists on its application for improving specific women's health issues across the lifespan. Consequently, there is a growing need among health professionals who care for women for a textbook that addresses evidence-based lifestyle solutions to manage the health challenges they face every day in their offices. This book begins with a review of the fundamentals of Lifestyle Medicine through the lens of a woman's lifespan. It provides information about lifestyle interventions to improve gynecologic and sexual health and to manage and sometimes reverse gynecologic diseases. It clarifies the importance of lifestyle and behaviors before and during pregnancy to address infertility, reduce adverse pregnancy outcomes, and to lower non-communicable diseases in children along with emerging epigenetic evidence. The use of Lifestyle Medicine to prevent and manage breast and gynecologic cancers, enhance health as part of cancer survivorship, and decrease the risk or reduce many of the symptoms and diseases experienced during menopause including vasomotor symptoms and osteoporosis are also discussed. Additionally, the text covers cardiovascular disease, diabetes, autoimmune disorders, dementia and mental health from the perspective of gender specific differences. This book provides practical resources on implementing the components of lifestyle medicine. Some of the topics covered include models of care for women and families, reimbursement, health coaching and behavioral change, community engagement and health equity for under-resourced settings. The electronic version of the book presents supplemental material featuring in-depth reading, as well as online and digital resources for implementing Lifestyle Medicine. The book is an evidence-based source of information on women's health issues for health professionals already practicing lifestyle medicine, as well as an entry level textbook for those new to the field of lifestyle medicine. The collective expertise of each of the editors along with content provided by leaders within the American College of Lifestyle Medicine fills a much-needed void within the specialty of Lifestyle Medicine and is for providers of women's health globally. Features: Provides a basic overview of Lifestyle Medicine (nutrient-rich diet, exercise, stress resilience, sleep, and high-quality connections) in the care of women across the lifespan. Provides lifestyle-focused treatment recommendations for specific women health issues. Includes strategies for implementing Lifestyle Medicine with vulnerable populations and in communities. Summarizes key points at the close of each chapter and includes supplemental material with in-depth reading. Features additional resources for implementing lifestyle medicine into practice. "This women's health book is evidence based and comprehensive. There is nothing like it. Women need up to date information about physical activity, nutrition, sleep, stress resilience, social connection and substance use. In addition, there is a desire to better understand the power of these pillars throughout a woman's life including pregnancy, menopause and the golden years. This book fills that need." Elizabeth Pegg Frates, MD, DipABLM, FACLM, President Elect of the American College of Lifestyle Medicine "Healthy aging begins at pre-conception. Evidence overwhelmingly shows that it's we women who-through our lifestyle behavior choices-can take far greater control of our own health destinies, as well as the health destinies of our children and generations to come. We cannot underestimate the power of what we eat, how we move, and what we think in regard to our optimal health or lack thereof. This book is a must-read for all medical professionals!" Susan Benigas, Executive Director of the American College of Lifestyle Medicine Lifestyle Medicine is the science of taking core principles and customizing how they're applied to each individual and each situation to achieve positive health behavior change. This book sets the evidence based foundation for how that process happens, and why it needs to happen, with the most important segment of health consumers - women. It is the next for all who are passionate about changing how health care is delivered." Wayne S. Dysinger, MD, MPH, Physician, Founder and Chair, Lifestyle Medical "Lifestyle factors have a powerful role in chronic disease prevention, underscoring the profound control we have over our health. Improving Women's Health Across the Lifespan applies lifestyle medicine to women's health, empowering women and their clinicians with the tools to transform their lives, and fostering a legacy of health for future generations." JoAnn E. Manson, MD, MPH, DrPH, Professor of Medicine and the Michael and Lee Bell Professor of Women's Health, Harvard Medical School Chief, Division of Preventive Medicine Brigham and Women's Hospital, Professor, Harvard Chan School of Public Health

This book brings together in one volume selected important topics in craniofacial growth. Topics include: principles of skeletal growth; osteogenesis and its control; formation of the cranial base and craniofacial joints; prenatal development of the facial skeleton; growth of the mandible, nasomaxillary complex, orbit, cranial base, ear capsule, and cranial vault; bone remodeling; muscles; soft tissues; and blood vessels.
Fundamentals of Craniofacial Growth contains detailed illustrations and extensive reference lists. Independently authored chapters provide comprehensive reviews encompassing both contemporary and historical perspectives. In addition to medicine and dentistry, contributors provide expertise from such diverse backgrounds as anatomy, biology, biomathematics, embryology, orthodontics, physical anthropology, and plastic and reconstructive surgery.

First published in 1967, Human Guinea Pigs is a report by a consultant physician on the implications of medical research on both the medical profession and on the men, women and children who are the subjects of medical experiments. It suggests that there are limits to the permissibility of experiments on humans. It points out how it has become a common occurrence for medical investigators to take risks with patients of which the patients themselves are frequently unaware, and to submit them to mental and physical distress and possible hazards which in no way are necessitated by or have connection with the treatment of the disease from which are suffering. The author describes a number of experiments which, in his opinion, raise important problems. In his view, medical research must go on, but there must be acknowledged and observed safeguards for patients. This book will be of interest to students of medicine, ethics, law, politics and social work.

This work offers succinct, medically-oriented coverage of biochemistry, examining biologically important materials and presenting the properties of nucleic acids as well as nucleic acid metabolism. Each metabolic process is integrated in a review of overall energy metabolism, diabetes and starvation. A solutions manual is available to instructors only.

Following on from the successful Biomechanics and Medicine in Swimming VI proceedings which covered the conference held in Liverpool, this book contains all twelve of the keynote addresses and selected, edited and revised papers presented at the Swimming Science VII conference in Atlanta. Leading international experts have contributed state-of-the-art research on the subject.

Science and technology has been used more and more in the last few decades to gain advantage over competitors. Quite often, however, the actual science involved is not published because a suitable journal cannot be found. The Engineering of Sport brings together work from a very diverse range of subjects including Engineering, Physics, Materials and Biomechanics.

The Engineering of Sport represent work which was represented at the 1st International Conference on the Engineering of Sport held in Sheffield, UK in July 1996. Many sports were represented and the material covered split into nine topics covering aerodynamics, biomechanics, design, dynamics, instrumentation, materials, mechanics, modelling, motion analysis, and vibrations. It should be of interest to specialists in all areas of sports research.

Applied Anatomy for the FRCA covers the anatomical knowledge that trainee anaesthetists who are revising for the Primary and Final FRCA exams will need. The topics covered are derived from the FRCA curriculum and include the most up-to-date version of past exam questions, in order to ensure targeted and successful exam revision. The content, illustrations and overall layout of this book ensure that common gaps in anatomical knowledge encountered by FRCA trainees are included. This reference is divided into sections pertaining to anatomical regions: head and neck, thorax, abdomen, spine, and the upper and lower limbs. The topics of importance to anaesthetists are presented under 'structures', 'circulation' and 'nervous system' (with relevance to regional anaesthesia). Each topic is extensively researched and presented in a simple format for maximum retention. This book makes learning and remembering applied anatomy as straightforward as possible. Applied Anatomy for the FRCA supplements the knowledge required by trainee anaesthetists appearing for the FRCA exams. Clinical educators will also find it useful in teaching. It serves as a practical reference for anatomical knowledge at any point in an anaesthetist's career. About the Editors Dr Bobby Krishnachetty has been a Consultant Anaesthetist at Southend University Hospital since 2010 and a college tutor for six years. She completed her diploma in medical education and is the author of The Final FRCA Structured Oral Examination: A Complete Guide. She is also the organiser of the regional teaching for Core trainees in the East of England school of anaesthesia, as well as Founder of the 'Southend Viva Club' Primary and Final FRCA SOE revision courses for more than nine years, and Cofounder of MRCS OSCE webinars. Mr Abdul Syed has been a Consultant Surgeon at Southend University Hospital since 2015. He is Lead for postgraduate teaching of surgical trainees, Cofounder of MRCS OSCE webinars and conducts Core surgical trainee interview skills courses. Mr Syed is also an Assessor for medical school interviews and an active participant in QI projects and research.

Covers research on gene drives in Anopheline mosquitoes for malaria control, including aspects from field trials, modelling, risk assessment, regulatory processes, and ethical/political considerations Includes contributions from international leaders in the field Illustrated throughout with figures and references

In Infertile Environments, Janelle Lamoreaux investigates how epigenetic research into the effects of toxic exposure conceptualizes and configures environments. Drawing on fieldwork in a Nanjing, China, toxicology lab that studies the influence of pesticides and other pollutants on male reproductive and developmental health, Lamoreaux shows how the lab's everyday research practices bring national, hormonal, dietary, maternal, and laboratory environments into being. She situates the lab's work within broader Chinese history as well as the contemporary cultural and political moment, in which declining fertility rates and reproductive governance and technology are growing concerns. She also points to how toxicology in China is a transnational endeavor tied to both local conditions and international research agendas and infrastructures, which highlights the myriad scales and scope of epigenetic environments. At a moment of growing concerns about toxins, endocrine-disrupting chemicals, and climate change, Lamoreaux demonstrates that epigenetic research's proliferation of environments produces new kinds of toxic relations that impact multiple generations of humans.

Frederic Delavier, the mastermind behind the bestselling Strength Training Anatomy phenomenon, delivers once again. More than two million readers have turned to his books to find the most effective exercises in strength training. Now, in The Strength Training Anatomy Workout III, Delavier and co-author Michael Gundhill picks up where Volume II left off. Strength Training Anatomy III is loaded with 146 of Delavier's unparalleled illustrations and 195 photos depicting proper exercise technique. These are supplemented with descriptions, explanation of muscle engagement and interactions, variations, benefits, limitations and safety considerations. You'll be able to assemble these exercises into advanced programmes for long-term strength and muscle development. Break past your training plateaus with high-tech strength training protocols like electrical stimulation, blood flow restriction and vibration and oscillation training. In the striking detail that only Frederic Delavier offers, The Strength Training Anatomy Workout III helps you cross the threshold to advanced muscle development and strength gains.

An outstanding piece of interdisciplinary scholarship, "The Body Emblazoned" is a study of the Renaissance culture of dissection which informed intellectual inquiry in Europe for nearly two hundred years. Though the dazzling displays in Renaissance art and literature of the "exterior" of the body have long been a subject of enquiry, Jonathan Sawday considers in detail the "interior" of the body, and what it meant to men and women in early modern culture.
Sawday links the frequently illicit activities of the great anatomists of the period, to whose labors we are indebted for so much of our understanding of the structure and operation of the human body, to a wider cultural discourse which embraces not only the great moments of Renaissance art, but the very foundation of a modern idea of knowledge. Illustrated with thirty-two black and white prints, "The Body Emblazoned" re-assesses modern understanding not only of the literature and culture of the Renaissance, but of the modern organization of knowledge which is now so familiar that it is only rarely questioned.

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neurological development 3) Appeals to neuroanatomists, developmental biologists and clinical practitioners. 4) Persistent relevance - brain development is not going to change

Since the early decades of the 20th century, the notion of the hormonally-constructed body has become the dominant mode of conceptualizing bodies, particularly female bodies, to such an extent that it is often assumed to be a natural phenomenon. This book challenges the idea that there is such a thing as a "natural" body and demonstrates that it is the process by which scientific claims achieve universal status that constructs such discourses as natural facts. The work tells the story of scientists' search for the many tons of ovaries, testes and urine that were required in experiments to develop the hormonal body concept. It traces the origins of sex hormones and follows their development through mass-production as drugs to their eventual transformation into the contraceptive pill.

This volume is a record of the proceedings of a festspiel held to honor Jozef F. Zwislocki for his outstanding contributions to science and to Syracuse University. His contributions to the knowledge of the hydromechanical, neurophysiological, and perceptual mechanisms of the auditory system are truly monumental. In addition, his contributions to the comprehension of the mammalian auditory system include not only landmark ideas, but also many of the experimental findings in psychoacoustics and peripheral auditory physiology that constitute the database which has provided a springboard for research in laboratories throughout the world. His efforts to link physics, biology, and psychophysics to create a basis for our understanding of the nervous system have had an influence that extends far beyond the science of acoustics.
Although the purpose of this conference was to recognize the many achievements of Professor Zwislocki, the spirit of the participants was to honor him in a manner that best characterized his lifetime dedication to research, that is, to report the results of their own work. Consequently, this volume is first and foremost a compilation of scientific papers in the area of sensory research. Some are reports of recent experiments and some present an overview of research efforts extending from the past up to ongoing work. His influence can be recognized in all of the contributions and some explicitly describe the ties between their own work and the germinal ideas planted by him. This volume, in reflecting the rapid progress being made in sensory science and written by those who are making it, is a fitting tribute to Zwislocki, who always stood at the forefront of his science.

The International Society for the Advancement of Kinanthropometry holds a major conference every four years. This volume contains a selection of papers presented at the fourth such event, held at the World Congress on Youth, Leisure and Physical Activity in Brussels. It represents state-of-the-art research in the field of physical development and physical performance with contributions from the UK, Europe, South America, USA and Canada. The papers are divided into four sections covering body composition and growth; physical activity, health and fitness; performance and anthropometry; and growth and performance.

The result of the first Appalachian Conference on neurodynamics, this volume focuses on processing in biological neural networks. How do brain processes become organized during decision making? That is, what are the neural antecedents that determine which course of action is to be pursued? Half of the contributions deal with modelling synapto-dendritic and neural ultrastructural processes; the remainder, with laboratory research findings, often cast in terms of the models. The interchanges at the conference and the ensuing publication also provide a foundation for further meetings. These will address how processes in different brain systems, coactive with the neural residues of experience and with sensory input, determine decisions.