Inflammation and Obesity: A New and Novel Approach to Manage Obesity and its Consequences is a comprehensive and up-to-date exploration of the correlation between obesity and inflammation. From the pathophysiology of obesity and inflammation, to the molecular mechanisms of obesity induced chronic inflammation, the book discusses how obesity and inflammation interact with other diseases. It highlights the hidden risk factors of obesity induced chronic inflammation, provides specific patient management guidelines regarding the higher inflammatory response in patients, and concludes with new therapeutic strategies to address inflammation in obese patients.

This volume of the Human Molecular Genetics series covers such genotype-phenotype correlations as clinical and environmental aspects, gene structure, expression, and mutation. Also discussed are models of certain diseases and future prospects for treatment and prevention. This book provides the reader with a basic overview of the physical expression of genetic disease before discussing in detail the most recent research and therapeutic developments.

This two volume set introduces the up-to-date high-tech applications of Aggregation-Induced Emission (AIE) luminogens in biosensing, bioimaging, and biomedicine. The 2nd volume presents the applications of AIE materials in biomedicine, including the utilizations in biomedical polymers, organic nanoprobes, photosensitizer, photothermal agents, AIEgens-based delivery systems, etc. It is an essential reference for materials scientists, chemists, physicists and biological chemists.

Properly utilized interprofessional education will prepare students in health professions to provide patient care in a collaborative team environment. Once healthcare professionals begin to work together in a collaborative interprofessional care team, patient care is improved. Building a Patient-Centered Interprofessional Education Program is a critical scholarly publication that provides readers with practical strategies to facilitate building effective interprofessional educational programs that both enrich learners and help to improve patient care. Featuring a wide range of topics including medical education, allopathic medicine, and telehealth, this book is ideal for curriculum developers, instructional designers, academicians, medical staff, teaching hospitals, healthcare educators, researchers, healthcare professionals, and students.

Clathrin-mediated endocytosis (CME) is a ubiquitous internalization process in eukaryotic cells. It consists of the formation of an approximately 50-nm diameter vesicle out of a flat membrane. Genetics, biochemistry, and microscopy experiments performed in the last four decades have been instrumental to discover and characterize major endocytic proteins in yeast and mammals. However, due to the highly dynamic nature of the endocytic assembly and its small size, many questions remain unresolved: how are endocytic proteins organized spatially and dynamically? How are forces produced and how are their directions controlled? How do the biochemical activities of endocytic proteins and the membrane shape and mechanics regulate each other? These questions are virtually impossible to visualize or measure directly with conventional approaches but thanks to new quantitative biology methods, it is now possible to infer the mechanisms of endocytosis in exquisite detail. This book introduces quantitative microscopy and mathematical modeling approaches that have been used to count the copy number of endocytic proteins, infer their localization with nanometer precision, and infer molecular and physical mechanisms that are involved in the robust formation of endocytic vesicles.

Students entering advanced study of environmental physiology may have little experience in researching environmental physiology or may not realize the depth and breadth of the field. "Advanced Environmental Exercise Physiology "offers the first complete look at the scope and major ideas of environmental exercise physiology. It provides students with a solid grounding in prominent research topics and a thorough understanding of the key concepts and current debates in the field. Using an integrative approach, " Advanced Environmental Exercise Physiology," the first book in Human Kinetics' Advanced Exercise Physiology series, considers the human capacity to exercise in and tolerate various environments. Readers will examine the major impact of each environment explored, and they will discover areas of current debate to stimulate further research. The text also helps students directly link the research to athletic and occupational situations in various environments. Through "Advanced Environmental Exercise Physiology, " students will learn the following: - The initial physiological responses upon exposure to an environment that a person is not adapted to - How the body adapts to repeated exposure to an environment - How various environments affect the ability to exercise and work - Individual variability in response to stressful environments Readers will also gain a firm knowledge of the application of basic exercise physiology to specific environmental stressors by looking at the countermeasures that people can take to minimize the impact of environmental stressors. Among the issues explored in this text are the effects of heat, hydration, and cold in the thermal environment; diving, altitude training, and other pressure effects on the human system; and the influences that pollution and air quality have on exercise. The text also explores the microgravity (space) environment and chronobiological rhythms and their effects on exercise performance. "Advanced Environmental Exercise Physiology" addresses the primary environmental factors affecting people when they are exercising and competing in sport, and it provides evidence-based information with numerous references. By linking research with recommendations for real-world situations, this text serves as an invaluable resource for students and professionals alike. Human Kinetics' Advanced Exercise Physiology series offers books for advanced undergraduate and graduate students as well as professionals in exercise science and kinesiology. These books highlight the complex interaction of the various systems both at rest and during exercise. Each text in this series offers a clear and concise explanation of the system and details how each is affected by acute exercise and chronic exercise training.

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.

In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part one of a two-part series on neuroimaging anatomy that focuses on the brain, with each article addressing a specific area. The issue also includes an article on Brain Connectomics: the study of the brain's structural and functional connections between cells. Contains 13 relevant, practice-oriented topics including anatomy of cerebral cortex, lobes, and the cerebellum; brainstem anatomy; cranial nerves anatomy; brain functional imaging anatomy; imaging of normal brain aging; and more. Provides in-depth clinical reviews on neuroimaging anatomy of the brain and skull, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Nutritional Modulators of Pain in the Aging Population provides an overview on the role of foods, dietary supplements, obesity, and nutrients in the prevention and amelioration of pain in various diseases in the aging population. Headaches, fibromyalgia, joint pain, arthritis pain, back pain, and stomach pain are discussed. In addition, the potential health risks of using foods to reduce symptoms is evaluated. Each chapter reviews pain causing conditions before reviewing the role of food or exercise. Both researchers and physicians will learn about dietary approaches that may benefit or harm people with various types of pain. Chapters include current research on the actions of nutrients in pain treatment, the effects of lifestyle and exercise on pain management, and discussions of dietary supplements that provide pain relief from chronic conditions like arthritis.

Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs.

Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed. Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration.

The content of medical education knowledge transfer is compounded as medical breakthroughs constantly impact treatment, and new diseases are discovered at an increasingly rapid pace. While much of the knowledge transfer remains unchanged throughout the generations, there are unique hallmarks to this generation's education, ranging from the impact of technology on learning formats to the use of standardized patients and virtual reality in the classroom. The Handbook of Research on the Efficacy of Training Programs and Systems in Medical Education is an essential reference source that focuses on key considerations in medical curriculum and content delivery and features new methods of knowledge and skill transfer. Featuring research on topics such as the generational workforce, medical accreditation, and professional development, this book is ideally designed for teachers, physicians, learning practitioners, IT consultants, higher education faculty, instructional designers, school administrators, researchers, academicians, and medical students seeking coverage on major and high-profile issues in medical education.